The saponins–polar isoprenoids with important and diverse biological activities A Osbourn, RJM Goss, RA Field Natural product reports 28 (7), 1261-1268, 2011 | 323 | 2011 |
Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis M Winn, RJM Goss, K Kimura, TDH Bugg Natural product reports 27 (2), 279-304, 2010 | 319 | 2010 |
A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus J Barke, RF Seipke, S Grüschow, D Heavens, N Drou, MJ Bibb, RJM Goss, ... BMC biology 8, 1-10, 2010 | 280 | 2010 |
Antiviral drug discovery: preparing for the next pandemic CS Adamson, K Chibale, RJM Goss, M Jaspars, DJ Newman, ... Chemical Society Reviews 50 (6), 3647-3655, 2021 | 212 | 2021 |
A serine carboxypeptidase-like acyltransferase is required for synthesis of antimicrobial compounds and disease resistance in oats ST Mugford, X Qi, S Bakht, L Hill, E Wegel, RK Hughes, K Papadopoulou, ... The Plant Cell 21 (8), 2473-2484, 2009 | 199 | 2009 |
A Single Streptomyces Symbiont Makes Multiple Antifungals to Support the Fungus Farming Ant Acromyrmex octospinosus RF Seipke, J Barke, C Brearley, L Hill, DW Yu, RJM Goss, MI Hutchings PLoS one 6 (8), e22028, 2011 | 198 | 2011 |
A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules J Reed, MJ Stephenson, K Miettinen, B Brouwer, A Leveau, P Brett, ... Metabolic Engineering 42, 185-193, 2017 | 182 | 2017 |
Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs AD Roy, S Grüschow, N Cairns, RJM Goss Journal of the American Chemical Society 132 (35), 12243-12245, 2010 | 173 | 2010 |
Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products JS Zarins-Tutt, TT Barberi, H Gao, A Mearns-Spragg, L Zhang, ... Natural product reports 33 (1), 54-72, 2016 | 152 | 2016 |
The generation of “unnatural” products: synthetic biology meets synthetic chemistry RJM Goss, S Shankar, A Abou Fayad Natural Product Reports 29 (8), 870-889, 2012 | 112 | 2012 |
Scope and potential of halogenases in biosynthetic applications DRM Smith, S Grüschow, RJM Goss Current opinion in chemical biology 17 (2), 276-283, 2013 | 106 | 2013 |
New pacidamycin antibiotics through precursor‐directed biosynthesis S Grüschow, EJ Rackham, B Elkins, PLA Newill, LM Hill, RJM Goss ChemBioChem 10 (2), 355-360, 2009 | 95 | 2009 |
Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 90 | 2023 |
Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster EJ Rackham, S Grüschow, AE Ragab, S Dickens, RJM Goss ChemBioChem 11 (12), 1700-1709, 2010 | 88 | 2010 |
A marine viral halogenase that iodinates diverse substrates DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ... Nature chemistry 11 (12), 1091-1097, 2019 | 79 | 2019 |
Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin BM Harvey, H Hong, MA Jones, ZA Hughes‐Thomas, RM Goss, ... ChemBioChem 7 (9), 1435-1442, 2006 | 74 | 2006 |
Halogenases: powerful tools for biocatalysis (mechanisms applications and scope) DS Gkotsi, J Dhaliwal, MMW McLachlan, KR Mulholand, RJM Goss Current Opinion in Chemical Biology 43, 119-126, 2018 | 71 | 2018 |
A convenient enzymatic synthesis of L-halotryptophans RJM Goss, PLA Newill Chemical communications, 4924-4925, 2006 | 71 | 2006 |
Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation C Crowe, S Molyneux, SV Sharma, Y Zhang, DS Gkotsi, H Connaris, ... Chemical Society Reviews 50 (17), 9443-9481, 2021 | 69 | 2021 |
The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans DRM Smith, T Willemse, DS Gkotsi, W Schepens, BUW Maes, S Ballet, ... Organic letters 16 (10), 2622-2625, 2014 | 67 | 2014 |