The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism X Xiong, R Tao, RA DePinho, XC Dong Journal of Biological Chemistry 287 (46), 39107-39114, 2012 | 224 | 2012 |
FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 … R Tao, X Xiong, RA DePinho, CX Deng, XC Dong Journal of Biological Chemistry 288 (41), 29252-29259, 2013 | 203 | 2013 |
Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 [S] R Tao, X Xiong, RA DePinho, CX Deng, XC Dong Journal of lipid research 54 (10), 2745-2753, 2013 | 198 | 2013 |
Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene R Tao, D Wei, H Gao, Y Liu, RA DePinho, XC Dong Journal of Biological Chemistry 286 (16), 14681-14690, 2011 | 153 | 2011 |
The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice WN Cong, RY Tao, JY Tian, GT Liu, F Ye Life sciences 82 (19-20), 983-990, 2008 | 125 | 2008 |
Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis X Xiong, R Tao, RA DePinho, XC Dong PloS one 8 (8), e74340, 2013 | 114 | 2013 |
Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling R Tao, X Xiong, S Liangpunsakul, XC Dong Diabetes 64 (4), 1211-1223, 2015 | 108 | 2015 |
Inactivating hepatic follistatin alleviates hyperglycemia R Tao, C Wang, O Stöhr, W Qiu, Y Hu, J Miao, XC Dong, S Leng, ... Nature medicine 24 (7), 1058-1069, 2018 | 97 | 2018 |
Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells X Xiong, G Wang, R Tao, P Wu, T Kono, K Li, WX Ding, X Tong, SA Tersey, ... Diabetologia 59 (1), 151-160, 2016 | 77 | 2016 |
PTP1B inhibitor improves both insulin resistance and lipid abnormalities in vivo and in vitro Y Ma, R Tao, Q Liu, J Li, J Tian, X Zhang, Z Xiao, F Ye Molecular and cellular biochemistry 357 (1), 65-72, 2011 | 71 | 2011 |
Genetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes R Tao, X Xiong, RA Harris, MF White, XC Dong PloS one 8 (8), e71997, 2013 | 64 | 2013 |
A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes S Zhang, S Liu, R Tao, D Wei, L Chen, W Shen, ZH Yu, L Wang, ... Journal of the American Chemical Society 134 (43), 18116-18124, 2012 | 62 | 2012 |
Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1 D Wei, R Tao, Y Zhang, MF White, XC Dong American Journal of Physiology-Endocrinology and Metabolism 300 (2), E312-E320, 2011 | 61 | 2011 |
Elevated circulating follistatin associates with an increased risk of type 2 diabetes C Wu, Y Borné, R Gao, M López Rodriguez, WC Roell, JM Wilson, ... Nature communications 12 (1), 1-10, 2021 | 52 | 2021 |
E4orf1 improves lipid and glucose metabolism in hepatocytes: a template to improve steatosis & hyperglycemia EJ Dhurandhar, R Krishnapuram, V Hegde, O Dubuisson, R Tao, ... Public Library of Science 7 (10), e47813, 2012 | 44 | 2012 |
Effect of Hypericum perforatum L. Extract on Insulin Resistance and Lipid Metabolic Disorder in High‐Fat‐Diet Induced Obese Mice J Tian, R Tao, X Zhang, Q Liu, Y He, Y Su, T Ji, F Ye Phytotherapy research 29 (1), 86-92, 2015 | 26 | 2015 |
Rhein, an inhibitor of adipocyte differentiation and adipogenesis Q Liu, XL Zhang, RY Tao, YJ Niu, XG Chen, JY Tian, F Ye Journal of Asian natural products research 13 (8), 714-723, 2011 | 26 | 2011 |
Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism ME Li, HPMM Lauritzen, BT O’Neill, CH Wang, W Cai, BB Brandao, ... Nature communications 10 (1), 1-14, 2019 | 24 | 2019 |
Improvement of high-fat-diet-induced metabolic syndrome by a compound from Balanophora polyandra Griff in mice R Tao, F Ye, Y He, J Tian, G Liu, T Ji, Y Su European Journal of Pharmacology 616 (1-3), 328-333, 2009 | 24 | 2009 |
FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance O Stöhr, R Tao, J Miao, KD Copps, MF White Cell reports 34 (12), 108893, 2021 | 23 | 2021 |