Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma RR Raval, KW Lau, MGB Tran, HM Sowter, SJ Mandriota, JL Li, CW Pugh, ... Molecular and cellular biology, 2005 | 1185 | 2005 |
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors MD Young, TJ Mitchell, FA Vieira Braga, MGB Tran, BJ Stewart, ... science 361 (6402), 594-599, 2018 | 586 | 2018 |
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 544 | 2018 |
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ... Nature 537 (7621), 544-547, 2016 | 529 | 2016 |
Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils S Wang, MB Voisin, KY Larbi, J Dangerfield, C Scheiermann, M Tran, ... The Journal of experimental medicine 203 (6), 1519-1532, 2006 | 476 | 2006 |
Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury P Hill, D Shukla, MGB Tran, J Aragones, HT Cook, P Carmeliet, ... Journal of the American Society of Nephrology 19 (1), 39-46, 2008 | 344 | 2008 |
Regulation of E-cadherin expression by VHL and hypoxia-inducible factor MA Esteban, MGB Tran, SK Harten, P Hill, MC Castellanos, A Chandra, ... Cancer research 66 (7), 3567-3575, 2006 | 343 | 2006 |
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor CE Massie, B Adryan, NL Barbosa‐Morais, AG Lynch, MG Tran, DE Neal, ... EMBO reports 8 (9), 871-878, 2007 | 302 | 2007 |
Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia DWJ Van Der Schaft, F Hillen, P Pauwels, DA Kirschmann, K Castermans, ... Cancer research 65 (24), 11520-11528, 2005 | 261 | 2005 |
Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein MA Esteban, SK Harten, MG Tran, PH Maxwell Journal of the American Society of Nephrology 17 (7), 1801-1806, 2006 | 186 | 2006 |
A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy N Pertega‐Gomes, S Felisbino, CE Massie, JR Vizcaino, R Coelho, ... The Journal of pathology 236 (4), 517-530, 2015 | 149 | 2015 |
Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution M Kovac, C Navas, S Horswell, M Salm, C Bardella, A Rowan, M Stares, ... Nature communications 6 (1), 6336, 2015 | 131 | 2015 |
Embryonal precursors of Wilms tumor THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ... Science 366 (6470), 1247-1251, 2019 | 129 | 2019 |
Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts RE Schietke, T Hackenbeck, M Tran, R Günther, B Klanke, CL Warnecke, ... PloS one 7 (1), e31034, 2012 | 102 | 2012 |
Fumarate induces vesicular release of mtDNA to drive innate immunity V Zecchini, V Paupe, I Herranz-Montoya, J Janssen, IMN Wortel, JL Morris, ... Nature 615 (7952), 499-506, 2023 | 98 | 2023 |
Effects of VHL Deficiency on Endolymphatic Duct and Sac S Gläsker, RR Lonser, MGB Tran, B Ikejiri, JA Butman, W Zeng, ... Cancer research 65 (23), 10847-10853, 2005 | 62 | 2005 |
Expression of hypoxia-inducible factors in normal human lung development P Rajatapiti, IWJM van der Horst, JD de Rooij, MGB Tran, PH Maxwell, ... Pediatric and Developmental Pathology 11 (3), 193-199, 2008 | 58 | 2008 |
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer R Li, JR Ferdinand, KW Loudon, GS Bowyer, S Laidlaw, F Muyas, ... Cancer Cell 40 (12), 1583-1599. e10, 2022 | 57 | 2022 |
Epididymal cystadenomas and epithelial tumourlets: effects of VHL deficiency on the human epididymis S Gläsker, MGB Tran, SB Shively, B Ikejiri, RR Lonser, PH Maxwell, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 55 | 2006 |
First-in-human in vivo non-invasive assessment of intra-tumoral metabolic heterogeneity in renal cell carcinoma M Tran, A Latifoltojar, JB Neves, MV Papoutsaki, F Gong, A Comment, ... BJR| case reports 5 (3), 20190003, 2019 | 53 | 2019 |