| The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ... Glia 68 (2), 407-421, 2020 | 162 | 2020 |
| Prion-like propagation of protein misfolding and aggregation in amyotrophic lateral sclerosis L McAlary, SS Plotkin, JJ Yerbury, NR Cashman Frontiers in molecular neuroscience 12, 262, 2019 | 137 | 2019 |
| CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1) G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1 JM Silverman, D Christy, CC Shyu, KM Moon, S Fernando, Z Gidden, ... Journal of Biological Chemistry 294 (10), 3744-3759, 2019 | 129 | 2019 |
| The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation MJ Capper, GSA Wright, L Barbieri, E Luchinat, E Mercatelli, L McAlary, ... Nature communications 9 (1), 1693, 2018 | 97 | 2018 |
| Susceptibility of mutant SOD1 to form a destabilized monomer predicts cellular aggregation and toxicity but not in vitro aggregation propensity L McAlary, JA Aquilina, JJ Yerbury Frontiers in neuroscience 10, 231906, 2016 | 94 | 2016 |
| Proteome homeostasis dysfunction: a unifying principle in ALS pathogenesis JJ Yerbury, NE Farrawell, L McAlary Trends in Neurosciences 43 (5), 274-284, 2020 | 57 | 2020 |
| Glutathionylation potentiates benign superoxide dismutase 1 variants to the toxic forms associated with amyotrophic lateral sclerosis L McAlary, JJ Yerbury, JA Aquilina Scientific reports 3 (1), 3275, 2013 | 53 | 2013 |
| SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS NE Farrawell, I Lambert-Smith, K Mitchell, J McKenna, L McAlary, ... Journal of cell science 131 (11), jcs209122, 2018 | 46 | 2018 |
| Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells E Pokrishevsky, L McAlary, N Farrawell, B Zhao, M Sher, JJ Yerbury, ... Scientific Reports 8, 2018 | 45 | 2018 |
| Amyotrophic lateral sclerosis: proteins, proteostasis, prions, and promises L McAlary, YL Chew, JS Lum, NJ Geraghty, JJ Yerbury, NR Cashman Frontiers in Cellular Neuroscience 14, 581907, 2020 | 35 | 2020 |
| Rapid flow cytometric measurement of protein inclusions and nuclear trafficking DR Whiten, R San Gil, L McAlary, JJ Yerbury, H Ecroyd, MR Wilson Scientific Reports 6 (1), 31138, 2016 | 34 | 2016 |
| Ubiquitin homeostasis is disrupted in TDP-43 and FUS cell models of ALS NE Farrawell, L McAlary, JS Lum, CG Chisholm, ST Warraich, IP Blair, ... Iscience 23 (11), 2020 | 32 | 2020 |
| Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E J Robert, EB Button, EM Martin, L McAlary, Z Gidden, M Gilmour, G Boyce, ... Molecular neurodegeneration 15, 1-21, 2020 | 31 | 2020 |
| Flow cytometric measurement of the cellular propagation of TDP-43 aggregation R Zeineddine, DR Whiten, NE Farrawell, L McAlary, MA Hanspal, ... Prion 11 (3), 195-204, 2017 | 30 | 2017 |
| Emerging developments in targeting proteotoxicity in neurodegenerative diseases L McAlary, SS Plotkin, NR Cashman CNS drugs 33 (9), 883-904, 2019 | 26 | 2019 |
| Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection A Crown, L McAlary, E Fagerli, H Brown, JJ Yerbury, A Galaleldeen, ... PloS one 15 (1), e0227655, 2020 | 25 | 2020 |
| The prion-like nature of amyotrophic lateral sclerosis L McAlary, JJ Yerbury, NR Cashman Progress in Molecular Biology and Translational Science 175, 261-296, 2020 | 22 | 2020 |
| CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper–Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding NE Farrawell, MR Yerbury, SS Plotkin, L McAlary, JJ Yerbury ACS chemical neuroscience 10 (3), 1555-1564, 2018 | 20 | 2018 |
| A copper chaperone–mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis L McAlary, VK Shephard, GSA Wright, JJ Yerbury Journal of Biological Chemistry 298 (3), 2022 | 12 | 2022 |
| Trajectory taken by dimeric Cu/Zn superoxide dismutase through the protein unfolding and dissociation landscape is modulated by salt bridge formation L McAlary, JA Harrison, JA Aquilina, SP Fitzgerald, C Kelso, JLP Benesch, ... Analytical chemistry 92 (2), 1702-1711, 2019 | 12 | 2019 |
Justin YerburyProf. in Neurodegenerative Disease, University of Wollongong, Illawarra Health and Medical Research在 uow.edu.au 的电子邮件经过验证
