Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids ACF Bolhaqueiro, B Ponsioen, B Bakker, SJ Klaasen, E Kucukkose, ... Nature genetics 51 (5), 824-834, 2019 | 201 | 2019 |
Genomic characterization of colistin heteroresistance in Klebsiella pneumoniae during a nosocomial outbreak T Halaby, E Kucukkose, AB Janssen, MRC Rogers, DJ Doorduijn, ... Antimicrobial agents and chemotherapy 60 (11), 6837-6843, 2016 | 87 | 2016 |
A review of the sensitivity of metastatic colorectal cancer patients with deficient mismatch repair to standard-of-care chemotherapy and monoclonal antibodies, with … E Wensink, M Bond, E Kucukkose, A May, G Vink, M Koopman, ... Cancer Treatment Reviews 95, 102174, 2021 | 21 | 2021 |
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice E Küçükköse, BA Heesters, J Villaudy, A Verheem, M Cercel, S Van Hal, ... Journal for Immunotherapy of Cancer 10 (12), 2022 | 20 | 2022 |
BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis J Laoukili, S van Schelven, E Küçükköse, A Verheem, K Goey, ... Cell reports 41 (9), 2022 | 7 | 2022 |
KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer E Küçükköse, NA Peters, I Ubink, VAM van Keulen, R Daghighian, ... Cell death & disease 13 (7), 617, 2022 | 7 | 2022 |
Mismatch repair status in patient-derived colorectal cancer organoids does not affect intrinsic tumor cell sensitivity to systemic therapy E Küçükköse, GE Wensink, CM Roelse, SJ van Schelven, DAE Raats, ... Cancers 13 (21), 5434, 2021 | 5 | 2021 |
Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer E Küçükköse, J Laoukili, AN Gorelick, S Degner, MM Laclé, ... Gastroenterology 165 (2), 429-444. e15, 2023 | 3 | 2023 |
Abstract LB301: BRAFV600E drives WNT signalling in colorectal cancer via aberrant DNA methylation LE Bouazzaoui, JM Bugter, E Küçükköse, A Verheem, JB Post, ... Cancer Research 84 (7_Supplement), LB301-LB301, 2024 | | 2024 |
Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer E Küçükköse, MJD Baars, M Amini, SJ Schraa, E Floor, GM Bol, ... British Journal of Cancer 130 (2), 213-223, 2024 | | 2024 |
Modeling metastatic colorectal cancer subtypes to improve therapeutic strategies E Küçükköse Utrecht University, 2023 | | 2023 |
RNF43 mutations facilitate mucinous colorectal cancer metastasis via formation of a tumour-intrinsic niche JM Bugter, L El Bouazzaoui, E Küçükköse, Y Hong, J Sprangers, ... bioRxiv, 2022.12. 22.521159, 2022 | | 2022 |
Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy. Cancers 2021, 13, 5434 E Küçükköse, GE Wensink, CM Roelse, SJ van Schelven, DAE Raats, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | | 2021 |
Quiescent Cells in Colorectal Cancer Liver Micro-and Macrometastases are Transcriptionally Distinct NA Peters, MC Heinz, E Kucukkose, B Viergever, M Baars, A Verheem, ... Cellular Heterogeneity during Metastatic Colonization of Colorectal Cancer, 183, 0 | | |