| Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in a golden Syrian hamster model: implications for disease pathogenesis and … JFW Chan, AJ Zhang, S Yuan, VKM Poon, CCS Chan, ACY Lee, ... Clinical infectious diseases 71 (9), 2428-2446, 2020 | 1208 | 2020 |
| Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus BJ Zheng, KW Chan, YP Lin, GY Zhao, C Chan, HJ Zhang, HL Chen, ... Proceedings of the National Academy of Sciences 105 (23), 8091-8096, 2008 | 362 | 2008 |
| Surgical mask partition reduces the risk of noncontact transmission in a golden Syrian hamster model for coronavirus disease 2019 (COVID-19) JFW Chan, S Yuan, AJ Zhang, VKM Poon, CCS Chan, ACY Lee, Z Fan, ... Clinical infectious diseases 71 (16), 2139-2149, 2020 | 292 | 2020 |
| SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 235 | 2019 |
| Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 202 | 2021 |
| Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs JFW Chan, CCY Yip, JOL Tsang, KM Tee, JP Cai, KKH Chik, Z Zhu, ... Emerging microbes & infections 5 (1), 1-12, 2016 | 185 | 2016 |
| Analytical modeling of open-circuit air-gap field distributions in multisegment and multilayer interior permanent-magnet machines L Zhu, SZ Jiang, ZQ Zhu, CC Chan IEEE Transactions on Magnetics 45 (8), 3121-3130, 2009 | 170 | 2009 |
| A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses H Zhao, J Zhou, K Zhang, H Chu, D Liu, VKM Poon, CCS Chan, ... Scientific reports 6 (1), 22008, 2016 | 169 | 2016 |
| Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces … L Du, G Zhao, Y Lin, H Sui, C Chan, S Ma, Y He, S Jiang, C Wu, KY Yuen, ... The Journal of Immunology 180 (2), 948-956, 2008 | 153 | 2008 |
| Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VK Man Poon, ... Science 377 (6604), 428-433, 2022 | 139 | 2022 |
| Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity L Du, G Zhao, CCS Chan, S Sun, M Chen, Z Liu, H Guo, Y He, Y Zhou, ... Virology 393 (1), 144-150, 2009 | 138 | 2009 |
| Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor JFW Chan, KKH Chik, S Yuan, CCY Yip, Z Zhu, KM Tee, JOL Tsang, ... Antiviral research 141, 29-37, 2017 | 134 | 2017 |
| Leptin mediates the pathogenesis of severe 2009 pandemic influenza A (H1N1) infection associated with cytokine dysregulation in mice with diet-induced obesity AJX Zhang, KKW To, C Li, CCY Lau, VKM Poon, CCS Chan, BJ Zheng, ... The Journal of infectious diseases 207 (8), 1270-1280, 2013 | 134 | 2013 |
| Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo S Yuan, JFW Chan, H den-Haan, KKH Chik, AJ Zhang, CCS Chan, ... Antiviral research 145, 33-43, 2017 | 132 | 2017 |
| Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters ACY Lee, AJ Zhang, JFW Chan, C Li, Z Fan, F Liu, Y Chen, R Liang, ... Cell Reports Medicine 1 (7), 2020 | 128 | 2020 |
| Emerging SARS-CoV-2 variants expand species tropism to murines H Shuai, JFW Chan, TTT Yuen, C Yoon, JC Hu, L Wen, B Hu, D Yang, ... EBioMedicine 73, 2021 | 126 | 2021 |
| Severe acute respiratory syndrome coronavirus 2 infects and damages the mature and immature olfactory sensory neurons of hamsters AJ Zhang, ACY Lee, H Chu, JFW Chan, Z Fan, C Li, F Liu, Y Chen, ... Clinical infectious diseases 73 (2), e503-e512, 2021 | 123 | 2021 |
| An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses G Zhao, Y Lin, L Du, J Guan, S Sun, H Sui, Z Kou, CCS Chan, Y Guo, ... Virology journal 7, 1-8, 2010 | 112 | 2010 |
| Coinfection by severe acute respiratory syndrome coronavirus 2 and influenza A (H1N1) pdm09 virus enhances the severity of pneumonia in golden Syrian hamsters AJ Zhang, ACY Lee, JFW Chan, F Liu, C Li, Y Chen, H Chu, SY Lau, ... Clinical infectious diseases 72 (12), e978-e992, 2021 | 108 | 2021 |
| Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies D Zhou, JFW Chan, B Zhou, R Zhou, S Li, S Shan, L Liu, AJ Zhang, ... Cell host & microbe 29 (4), 551-563. e5, 2021 | 105 | 2021 |
