Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling H Wen, D Gris, Y Lei, S Jha, L Zhang, MTH Huang, WJ Brickey, JPY Ting Nature immunology 12 (5), 408-415, 2011 | 1865 | 2011 |
Astrocytes maintain glutamate homeostasis in the CNS by controlling the balance between glutamate uptake and release S Mahmoud, M Gharagozloo, C Simard, D Gris Cells 8 (2), 184, 2019 | 535 | 2019 |
Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells RR Craven, X Gao, IC Allen, D Gris, JB Wardenburg, ... PloS one 4 (10), e7446, 2009 | 503 | 2009 |
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses D Gris, Z Ye, HA Iocca, H Wen, RR Craven, P Gris, M Huang, M Schneider, ... The Journal of Immunology 185 (2), 974-981, 2010 | 446 | 2010 |
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways IC Allen, CB Moore, M Schneider, Y Lei, BK Davis, MA Scull, D Gris, ... Immunity 34 (6), 854-865, 2011 | 402 | 2011 |
Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function D Gris, DR Marsh, MA Oatway, Y Chen, EF Hamilton, GA Dekaban, ... Journal of Neuroscience 24 (16), 4043-4051, 2004 | 398 | 2004 |
The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18 S Jha, SY Srivastava, WJ Brickey, H Iocca, A Toews, JP Morrison, ... Journal of Neuroscience 30 (47), 15811-15820, 2010 | 349 | 2010 |
Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures M Hakimi, T Selvanantham, E Swinton, RF Padmore, Y Tong, G Kabbach, ... Journal of neural transmission 118, 795-808, 2011 | 312 | 2011 |
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity JC Arthur, JD Lich, Z Ye, IC Allen, D Gris, JE Wilson, M Schneider, ... The Journal of Immunology 185 (8), 4515-4519, 2010 | 164 | 2010 |
The systemic inflammatory response after spinal cord injury damages lungs and kidneys D Gris, EF Hamilton, LC Weaver Experimental neurology 211 (1), 259-270, 2008 | 159 | 2008 |
Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention LC Weaver, DR Marsh, D Gris, A Brown, GA Dekaban Progress in brain research 152, 245-263, 2006 | 145 | 2006 |
The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome DJ Taxman, EA Holley-Guthrie, MTH Huang, CB Moore, DT Bergstralh, ... Journal of Biological Chemistry 286 (22), 19605-19616, 2011 | 91 | 2011 |
NLR-dependent regulation of inflammation in multiple sclerosis M Gharagozloo, KV Gris, T Mahvelati, A Amrani, JR Lukens, D Gris Frontiers in immunology 8, 2012, 2018 | 90 | 2018 |
Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis MTH Huang, BL Mortensen, DJ Taxman, RR Craven, S Taft-Benz, ... The Journal of Immunology 185 (9), 5476-5485, 2010 | 82 | 2010 |
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism P Gris, J Gauthier, P Cheng, DG Gibson, D Gris, O Laur, J Pierson, ... Molecular pain 6, 1744-8069-6-33, 2010 | 81 | 2010 |
Cyanotoxins at low doses induce apoptosis and inflammatory effects in murine brain cells: Potential implications for neurodegenerative diseases L Takser, N Benachour, B Husk, H Cabana, D Gris Toxicology reports 3, 180-189, 2016 | 71 | 2016 |
Methylprednisolone causes minimal improvement after spinal cord injury in rats, contrasting with benefits of an anti-integrin treatment LC Weaver, D Gris, LR Saville, MA Oatway, Y Chen, DR Marsh, ... Journal of neurotrauma 22 (12), 1375-1387, 2005 | 64 | 2005 |
Loss of NLRX1 exacerbates neural tissue damage and NF-κB signaling following brain injury MH Theus, T Brickler, AL Meza, S Coutermarsh-Ott, A Hazy, D Gris, ... The Journal of Immunology 199 (10), 3547-3558, 2017 | 63 | 2017 |
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia … TK Eitas, WC Chou, H Wen, D Gris, GR Robbins, J Brickey, Y Oyama, ... Journal of Biological Chemistry 289 (7), 4173-4179, 2014 | 62 | 2014 |
Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease C Vilariño-Güell, A Zimprich, F Martinelli-Boneschi, B Herculano, Z Wang, ... PLoS genetics 15 (6), e1008180, 2019 | 58 | 2019 |