| Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4 HM Herz, M Mohan, AS Garruss, K Liang, Y Takahashi, K Mickey, O Voets, ... Genes & development 26 (23), 2604-2620, 2012 | 412 | 2012 |
| Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing K Liang, X Gao, JM Gilmore, L Florens, MP Washburn, E Smith, ... Molecular and cellular biology 35 (6), 928-938, 2015 | 206 | 2015 |
| Human TFIIH kinase CDK7 regulates transcription-associated chromatin modifications CC Ebmeier, B Erickson, BL Allen, MA Allen, H Kim, N Fong, JR Jacobsen, ... Cell reports 20 (5), 1173-1186, 2017 | 142 | 2017 |
| Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase H Zheng, Y Qi, S Hu, X Cao, C Xu, Z Yin, X Chen, Y Li, W Liu, J Li, J Wang, ... Science 370 (6520), eabb5872, 2020 | 140 | 2020 |
| Estrogen stimulates degradation of β-amyloid peptide by up-regulating neprilysin K Liang, L Yang, C Yin, Z Xiao, J Zhang, Y Liu, J Huang Journal of Biological Chemistry 285 (2), 935-942, 2010 | 132 | 2010 |
| Therapeutic targeting of MLL degradation pathways in MLL-rearranged leukemia K Liang, AG Volk, JS Haug, SA Marshall, AR Woodfin, ET Bartom, ... Cell 168 (1), 59-72. e13, 2017 | 126 | 2017 |
| Mitotic transcriptional activation: clearance of actively engaged Pol II via transcriptional elongation control in mitosis K Liang, AR Woodfin, BD Slaughter, JR Unruh, AC Box, RA Rickels, ... Molecular cell 60 (3), 435-445, 2015 | 120 | 2015 |
| Targeting processive transcription elongation via SEC disruption for MYC-induced cancer therapy K Liang, ER Smith, Y Aoi, KL Stoltz, H Katagi, AR Woodfin, EJ Rendleman, ... Cell 175 (3), 766-779. e17, 2018 | 107 | 2018 |
| A CHAF1B-dependent molecular switch in hematopoiesis and leukemia pathogenesis A Volk, K Liang, P Suraneni, X Li, J Zhao, M Bulic, S Marshall, K Pulakanti, ... Cancer cell 34 (5), 707-723. e7, 2018 | 75 | 2018 |
| A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism L Wang, CK Collings, Z Zhao, KA Cozzolino, Q Ma, K Liang, SA Marshall, ... Genes & development 31 (20), 2056-2066, 2017 | 71 | 2017 |
| Genomic profiling of native R loops with a DNA-RNA hybrid recognition sensor K Wang, H Wang, C Li, Z Yin, R Xiao, Q Li, Y Xiang, W Wang, J Huang, ... Science advances 7 (8), eabe3516, 2021 | 64 | 2021 |
| Ligand-induced native G-quadruplex stabilization impairs transcription initiation C Li, H Wang, Z Yin, P Fang, R Xiao, Y Xiang, W Wang, Q Li, B Huang, ... Genome research 31 (9), 1546-1560, 2021 | 63 | 2021 |
| YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation J Li, K Chen, X Dong, Y Xu, Q Sun, H Wang, Z Chen, C Liu, R Liu, Z Yang, ... Cell proliferation 55 (1), e13157, 2022 | 58 | 2022 |
| DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation K Cao, M Ugarenko, PA Ozark, J Wang, SA Marshall, EJ Rendleman, ... Proceedings of the National Academy of Sciences 117 (44), 27365-27373, 2020 | 49 | 2020 |
| R-loop-dependent promoter-proximal termination ensures genome stability C Xu, C Li, J Chen, Y Xiong, Z Qiao, P Fan, C Li, S Ma, J Liu, A Song, ... Nature 621 (7979), 610-619, 2023 | 31 | 2023 |
| CDK9 inhibitor induces the apoptosis of B-cell acute lymphocytic leukemia by inhibiting c-Myc-mediated glycolytic metabolism WL Huang, T Abudureheman, J Xia, L Chu, H Zhou, WW Zheng, N Zhou, ... Frontiers in cell and developmental biology 9, 641271, 2021 | 20 | 2021 |
| Close correlation between development of MODS during the initial 72 h of hospitalization and hospital mortality in severe fever with thrombocytopenia syndrome S Jie, Y Zhou, L Sun, K Liang, X Yi, H Li Journal of Huazhong University of Science and Technology [Medical Sciences …, 2013 | 20 | 2013 |
| Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia F Zheng, H Li, K Liang, Y Du, D Guo, S Huang Medical Oncology 29, 2127-2135, 2012 | 16 | 2012 |
| Discovery of a novel class of PROTACs as potent and selective estrogen receptor α degraders to overcome endocrine-resistant breast cancer in vitro and in vivo B Xie, Z Yin, Z Hu, J Lv, C Du, X Deng, Y Huang, Q Li, J Huang, K Liang, ... Journal of Medicinal Chemistry 66 (10), 6631-6651, 2023 | 15 | 2023 |
| Multiple‐targeting and conformational selection in the estrogen receptor: computation and experiment P Yuan, K Liang, B Ma, N Zheng, R Nussinov, J Huang Chemical biology & drug design 78 (1), 137-149, 2011 | 15 | 2011 |
Ali ShilatifardProfessor and Chairman of Biochemistry, Director of Simpson Querrey Institute for Epigenetics在 northwestern.edu 的电子邮件经过验证
