Tyramine functions independently of octopamine in the Caenorhabditis elegans nervous system MJ Alkema, M Hunter-Ensor, N Ringstad, HR Horvitz Neuron 46 (2), 247-260, 2005 | 446 | 2005 |
Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans AM Leifer, C Fang-Yen, M Gershow, MJ Alkema, ADT Samuel Nature methods 8 (2), 147-152, 2011 | 381 | 2011 |
Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. MJ Alkema, M Bronk, E Verhoeven, A Otte, LJ van't Veer, A Berns, ... Genes & development 11 (2), 226-240, 1997 | 326 | 1997 |
The DNA binding specificity of the bipartite POU domain and its subdomains. CP Verrijzer, MJ Alkema, WW Van Weperen, HC Van Leeuwen, ... The EMBO journal 11 (13), 4993-5003, 1992 | 318 | 1992 |
A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors CA Grove, F De Masi, MI Barrasa, DE Newburger, MJ Alkema, ML Bulyk, ... Cell 138 (2), 314-327, 2009 | 306 | 2009 |
Pan-neuronal imaging in roaming Caenorhabditis elegans V Venkatachalam, N Ji, X Wang, C Clark, JK Mitchell, M Klein, CJ Tabone, ... Proceedings of the National Academy of Sciences 113 (8), E1082-E1088, 2016 | 231 | 2016 |
Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression T Akasaka, M Lohuizen, N Lugt, Y Mizutani-Koseki, M Kanno, ... Development 128 (9), 1587-1597, 2001 | 221 | 2001 |
RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor DPE Satijn, MJ Gunster, J van der Vlag, KM Hamer, W Schul, MJ Alkema, ... Molecular and cellular biology 17 (7), 4105-4113, 1997 | 218 | 1997 |
Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice MJ Alkema, NMT van der Lugt, RC Bobeldijk, A Berns, M van Lohuizen Nature 374 (6524), 724-727, 1995 | 210 | 1995 |
Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic MJ Gunster, DP Satijn, KM Hamer, JL den Blaauwen, D de Bruijn, ... Molecular and cellular biology, 1997 | 199 | 1997 |
Characterization and chromosomal localization of the human proto-oncogene BMI-1 M Alkema, J Wiegant, AK Raap, A Bems, M van Lohuizen Human molecular genetics 2 (10), 1597-1603, 1993 | 196 | 1993 |
A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response JK Pirri, AD McPherson, JL Donnelly, MM Francis, MJ Alkema Neuron 62 (4), 526-538, 2009 | 185 | 2009 |
The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression NMT van der Lugt, M Alkema, A Berns, J Deschamps Mechanisms of development 58 (1-2), 153-164, 1996 | 185 | 1996 |
Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger MJ Alkema, H Jacobs, M van Lohuizen, A Berns Oncogene 15 (8), 899-910, 1997 | 163 | 1997 |
Monoaminergic Orchestration of Motor Programs in a Complex C. elegans Behavior JL Donnelly, CM Clark, AM Leifer, JK Pirri, M Haburcak, MM Francis, ... PLoS biology 11 (4), e1001529, 2013 | 161 | 2013 |
Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling AC Koon, J Ashley, R Barria, S DasGupta, R Brain, S Waddell, MJ Alkema, ... Nature neuroscience 14 (2), 190-199, 2011 | 147 | 2011 |
The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length DE Cook, S Zdraljevic, RE Tanny, B Seo, DD Riccardi, LM Noble, ... Genetics 204 (1), 371-383, 2016 | 131 | 2016 |
Genetic interactions and dosage effects of Polycomb group genes in mice S Bel, N Coré, M Djabali, K Kieboom, NV Lugt, MJ Alkema, MV Lohuizen Development 125 (18), 3543-3551, 1998 | 109 | 1998 |
Excitatory motor neurons are local oscillators for backward locomotion S Gao, SA Guan, AD Fouad, J Meng, T Kawano, YC Huang, Y Li, ... Elife 7, e29915, 2018 | 102 | 2018 |
The C. elegans touch response facilitates escape from predacious fungi SM Maguire, CM Clark, J Nunnari, JK Pirri, MJ Alkema Current Biology 21 (15), 1326-1330, 2011 | 99 | 2011 |