In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project RS Judson, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ... Environmental health perspectives 118 (4), 485-492, 2010 | 603 | 2010 |
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ... Chemical research in toxicology 25 (7), 1287-1302, 2012 | 497 | 2012 |
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—an emerging role for gut microbiome S MahmoudianDehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xie, ... Alzheimer's & Dementia 15 (1), 76-92, 2019 | 487 | 2019 |
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment BA Wetmore, JF Wambaugh, SS Ferguson, MA Sochaski, DM Rotroff, ... Toxicological Sciences 125 (1), 157-174, 2012 | 461 | 2012 |
Metabolic network failures in Alzheimer's disease: A biochemical road map JB Toledo, M Arnold, G Kastenmüller, R Chang, RA Baillie, X Han, ... Alzheimer's & Dementia 13 (9), 965-984, 2017 | 403 | 2017 |
Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening DM Rotroff, BA Wetmore, DJ Dix, SS Ferguson, HJ Clewell, KA Houck, ... Toxicological Sciences 117 (2), 348-358, 2010 | 303 | 2010 |
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ... Toxicological Sciences 148 (1), 137-154, 2015 | 287 | 2015 |
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 286 | 2019 |
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ... Toxicological Sciences 152 (2), 323-339, 2016 | 260 | 2016 |
Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA’s ToxCast program MT Martin, DJ Dix, RS Judson, RJ Kavlock, DM Reif, AM Richard, ... Chemical research in toxicology 23 (3), 578-590, 2010 | 225 | 2010 |
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ... Environmental science & technology 44 (15), 5979-5985, 2010 | 220 | 2010 |
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin K Zhou, SW Yee, EL Seiser, N Van Leeuwen, R Tavendale, AJ Bennett, ... Nature genetics 48 (9), 1055-1059, 2016 | 202 | 2016 |
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway R Huang, S Sakamuru, MT Martin, DM Reif, RS Judson, KA Houck, ... Scientific reports 4 (1), 5664, 2014 | 167 | 2014 |
Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals DM Rotroff, DJ Dix, KA Houck, TB Knudsen, MT Martin, KW McLaurin, ... Environmental Health Perspectives 121 (1), 7-14, 2013 | 162 | 2013 |
Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database MT Martin, E Mendez, DG Corum, RS Judson, RJ Kavlock, DM Rotroff, ... Toxicological Sciences 110 (1), 181-190, 2009 | 138 | 2009 |
Gene set analysis methods: a systematic comparison R Mathur, D Rotroff, J Ma, A Shojaie, A Motsinger-Reif BioData mining 11, 1-19, 2018 | 106 | 2018 |
Development of a thyroperoxidase inhibition assay for high-throughput screening KB Paul, JM Hedge, DM Rotroff, MW Hornung, KM Crofton, SO Simmons Chemical research in toxicology 27 (3), 387-399, 2014 | 93 | 2014 |
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting … DM Rotroff, DG Corum, A Motsinger-Reif, O Fiehn, N Bottrel, WC Drevets, ... Translational psychiatry 6 (9), e894-e894, 2016 | 92 | 2016 |
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ... Environmental science & technology 48 (15), 8706-8716, 2014 | 79 | 2014 |
Continued muscle loss increases mortality in cirrhosis: impact of aetiology of liver disease N Welch, J Dasarathy, A Runkana, R Penumatsa, A Bellar, J Reen, ... Liver International 40 (5), 1178-1188, 2020 | 72 | 2020 |