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Christopher Jacques Lech
Christopher Jacques Lech
在 e.ntu.edu.sg 的电子邮件经过验证 - 首页
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引用次数
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Guanine base stacking in G-quadruplex nucleic acids
CJ Lech, B Heddi, AT Phan
Nucleic acids research 41 (3), 2034-2046, 2013
1442013
Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome
B De Nicola, CJ Lech, B Heddi, S Regmi, I Frasson, R Perrone, ...
Nucleic acids research 44 (13), 6442-6451, 2016
912016
Structure and conformational dynamics of a stacked dimeric G-quadruplex formed by the human CEB1 minisatellite
M Adrian, DJ Ang, CJ Lech, B Heddi, A Nicolas, AT Phan
Journal of the American Chemical Society 136 (17), 6297-6305, 2014
912014
High-resolution AFM structure of DNA G-wires in aqueous solution
K Bose, CJ Lech, B Heddi, AT Phan
Nature communications 9 (1), 1959, 2018
752018
Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplex
CJ Lech, JKC Lim, JMW Lim, S Amrane, B Heddi, AT Phan
Biophysical journal 101 (8), 1987-1998, 2011
642011
Sugar-modified G-quadruplexes: effects of LNA-, 2′ F-RNA–and 2′ F-ANA-guanosine chemistries on G-quadruplex structure and stability
Z Li, CJ Lech, AT Phan
Nucleic acids research, 4068-4079, 2013
512013
Electron-hole transfer in G-quadruplexes with different tetrad stacking geometries: a combined QM and MD study
CJ Lech, AT Phan, ME Michel-Beyerle, AA Voityuk
The Journal of Physical Chemistry B 117 (34), 9851-9856, 2013
502013
2′-F-ANA-guanosine and 2′-F-guanosine as powerful tools for structural manipulation of G-quadruplexes
CJ Lech, Z Li, B Heddi, AT Phan
Chemical Communications 48 (93), 11425-11427, 2012
472012
Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G· G· X· O tetrad
VV Cheong, B Heddi, CJ Lech, AT Phan
Nucleic acids research 43 (21), 10506-10514, 2015
412015
Inverting the G‐Tetrad Polarity of a G‐Quadruplex by Using Xanthine and 8‐Oxoguanine
VV Cheong, CJ Lech, B Heddi, AT Phan
Angewandte Chemie International Edition 55 (1), 160-163, 2016
372016
Influence of base stacking geometry on the nature of excited states in G-quadruplexes: A time-dependent DFT study
CJ Lech, AT Phan, ME Michel-Beyerle, AA Voityuk
The Journal of Physical Chemistry B 119 (9), 3697-3705, 2015
342015
Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification
CJ Lech, AT Phan
Nucleic acids research 45 (11), 6265-6274, 2017
152017
Influence of base stacking geometry on the nature of excited states in G-quadruplexes: a time-dependent DFT study
AT Phan, AA Voityuk, CJ Lech, ME Maria-Elisabeth
2015
Engineering G-quadruplex DNA: a combined computational and experimental study
CJ Lech
2013
47 Incorporation of alternative nucleic acid chemistries into G-quadruplex structure
CJ Lech, AT Phan
Journal of Biomolecular Structure and Dynamics 31 (sup1), 29-29, 2013
2013
Full wwPDB NMR Structure Validation Report i○
M Adrian, DJ Ang, C Lech, B Heddi, A Nicolas, AT Phan
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