| Development of curcumin–cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems GMAN Ntoutoume, R Granet, JP Mbakidi, F Brégier, DY Léger, ... Bioorganic & medicinal chemistry letters 26 (3), 941-945, 2016 | 205 | 2016 |
| Citral inhibits cell proliferation and induces apoptosis and cell cycle arrest in MCF‐7 cells W Chaouki, DY Leger, B Liagre, JL Beneytout, M Hmamouchi Fundamental & clinical pharmacology 23 (5), 549-556, 2009 | 172 | 2009 |
| Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells C Lepage, DY Léger, J Bertrand, F Martin, JL Beneytout, B Liagre Cancer letters 301 (2), 193-202, 2011 | 155 | 2011 |
| Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma H Janouskova, A Maglott, DY Leger, C Bossert, F Noulet, E Guerin, ... Cancer research 72 (14), 3463-3470, 2012 | 138 | 2012 |
| Photo-uncaging of a microtubule-targeted rigidin analogue in hypoxic cancer cells and in a xenograft mouse model VHS van Rixel, V Ramu, AB Auyeung, N Beztsinna, DY Leger, ... Journal of the American Chemical Society 141 (46), 18444-18454, 2019 | 115 | 2019 |
| α5β1 integrin antagonists reduce chemotherapy‐induced premature senescence and facilitate apoptosis in human glioblastoma cells E Martinkova, A Maglott, DY Leger, D Bonnet, M Stiborova, K Takeda, ... International Journal of Cancer 127 (5), 1240-1248, 2010 | 89 | 2010 |
| The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells Y Limami, A Pinon, DY Leger, E Pinault, C Delage, JL Beneytout, A Simon, ... Biochimie 94 (8), 1754-1763, 2012 | 88 | 2012 |
| Antiproliferative effect of extracts from Aristolochia baetica and Origanum compactum on human breast cancer cell line MCF-7 W Chaouki, DY Leger, J Eljastimi, JL Beneytout, M Hmamouchi Pharmaceutical Biology 48 (3), 269-274, 2010 | 82 | 2010 |
| Role of MAPKs and NF-κB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells DY Leger, B Liagre, JL Beneytout International journal of oncology 28 (1), 201-207, 2006 | 81 | 2006 |
| Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression DY Leger, B Liagre, C Corbière, J Cook-Moreau, JL Beneytout International journal of oncology 25 (3), 555-562, 2004 | 75 | 2004 |
| Photosensitizers used in the photodynamic therapy of rheumatoid arthritis M Gallardo-Villagrán, DY Leger, B Liagre, B Therrien International journal of molecular sciences 20 (13), 3339, 2019 | 72 | 2019 |
| HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death Y Limami, A Pinon, DY Leger, Y Mousseau, J Cook-Moreau, JL Beneytout, ... Biochimie 93 (4), 749-757, 2011 | 72 | 2011 |
| Diosgenin dose-dependent apoptosis and differentiation induction in human erythroleukemia cell line and sedimentation field-flow fractionation monitoring DY Léger, B Liagre, PJP Cardot, JL Beneytout, S Battu Analytical biochemistry 335 (2), 267-278, 2004 | 69 | 2004 |
| Diosgenin, a plant steroid, induces apoptosis in COX-2 deficient K562 cells with activation of the p38 MAP kinase signalling and inhibition of NF-κB binding B Liagre, J Bertrand, DY Leger, JL Beneytout International Journal of Molecular Medicine 16 (6), 1095-1101, 2005 | 62 | 2005 |
| Photodynamic therapy activity of new porphyrin-xylan-coated silica nanoparticles in human colorectal cancer L Bretin, A Pinon, S Bouramtane, C Ouk, L Richard, ML Perrin, ... Cancers 11 (10), 1474, 2019 | 59 | 2019 |
| Delivery of tanshinone IIA and α-mangostin from gold/PEI/cyclodextrin nanoparticle platform designed for prostate cancer chemotherapy S Qiu, R Granet, JP Mbakidi, F Brégier, C Pouget, L Micallef, ... Bioorganic & medicinal chemistry letters 26 (10), 2503-2506, 2016 | 58 | 2016 |
| Porphyrin-xylan-coated silica nanoparticles for anticancer photodynamic therapy S Bouramtane, L Bretin, A Pinon, D Leger, B Liagre, L Richard, F Brégier, ... Carbohydrate polymers 213, 168-175, 2019 | 54 | 2019 |
| Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes P Vergne-Salle, DY Léger, P Bertin, R Trèves, JL Beneytout, B Liagre Cytokine 31 (5), 335-348, 2005 | 43 | 2005 |
| Analysis of the in vitro and in vivo effects of photodynamic therapy on prostate cancer by using new photosensitizers, protoporphyrin IX-polyamine derivatives C Fidanzi-Dugas, B Liagre, G Chemin, A Perraud, C Carrion, CY Couquet, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (7), 1676-1690, 2017 | 36 | 2017 |
| Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents DY Leger, B Liagre, JL Beneytout Apoptosis 11 (10), 1747-1760, 2006 | 34 | 2006 |
