| Andecaliximab/GS-5745 alone and combined with mFOLFOX6 in advanced gastric and gastroesophageal junction adenocarcinoma: results from a phase I study MA Shah, A Starodub, S Sharma, J Berlin, M Patel, ZA Wainberg, ... Clinical Cancer Research 24 (16), 3829-3837, 2018 | 81 | 2018 |
| The role of select subtype polymorphisms on HIV-1 protease conformational sampling and dynamics X Huang, MD Britto, JL Kear-Scott, CD Boone, JR Rocca, C Simmerling, ... Journal of Biological Chemistry 289 (24), 17203-17214, 2014 | 62 | 2014 |
| Phase Ib study of tirabrutinib in combination with idelalisib or entospletinib in previously treated chronic lymphocytic leukemia AV Danilov, C Herbaux, HS Walter, P Hillmen, SA Rule, EA Kio, L Karlin, ... Clinical Cancer Research 26 (12), 2810-2818, 2020 | 59 | 2020 |
| Elucidating a relationship between conformational sampling and drug resistance in HIV-1 protease IMS de Vera, AN Smith, MCA Dancel, X Huang, BM Dunn, GE Fanucci Biochemistry 52 (19), 3278-3288, 2013 | 42 | 2013 |
| A new surfactant-fluorescence probe for detecting shape transitions in self-assembled systems L Gao, Q Song, X Huang, J Huang Journal of colloid and interface science 323 (2), 420-425, 2008 | 33 | 2008 |
| Effects of hinge-region natural polymorphisms on human immunodeficiency virus-type 1 protease structure, dynamics, and drug pressure evolution Z Liu, X Huang, L Hu, L Pham, KM Poole, Y Tang, BP Mahon, W Tang, ... Journal of Biological Chemistry 291 (43), 22741-22756, 2016 | 32 | 2016 |
| Inhibitor-induced conformational shifts and ligand-exchange dynamics for HIV-1 protease measured by pulsed EPR and NMR spectroscopy X Huang, IMS de Vera, AM Veloro, ME Blackburn, JL Kear, JD Carter, ... The Journal of Physical Chemistry B 116 (49), 14235-14244, 2012 | 32 | 2012 |
| Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts Z Liu, TM Casey, ME Blackburn, X Huang, L Pham, IMS de Vera, ... Physical Chemistry Chemical Physics 18 (8), 5819-5831, 2016 | 30 | 2016 |
| A surfactant type fluorescence probe for detecting micellar growth L Gao, L Zhao, X Huang, B Xu, Y Yan, J Huang Journal of colloid and interface science 354 (1), 256-260, 2011 | 19 | 2011 |
| Effects of PRE and POST therapy drug-pressure selected mutations on HIV-1 protease conformational sampling JD Carter, EG Gonzales, X Huang, AN Smith, IMS de Vera, PW D’Amore, ... FEBS letters 588 (17), 3123-3128, 2014 | 16 | 2014 |
| Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma F Morschhauser, MJS Dyer, HS Walter, AV Danilov, L Ysebaert, ... Leukemia 35 (7), 2108-2113, 2021 | 14 | 2021 |
| Backbone 1H, 13C, and 15N chemical shift assignment for HIV-1 protease subtypes and multi-drug resistant variant MDR 769 X Huang, IMS de Vera, AM Veloro, JR Rocca, C Simmerling, BM Dunn, ... Biomolecular NMR assignments 7, 199-202, 2013 | 12 | 2013 |
| A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of GS-5745 combined with mFOLFOX6 as first-line treatment in patients with … JC Bendell, A Starodub, X Huang, JD Maltzman, ZA Wainberg, MA Shah Journal of Clinical Oncology 35 (4_suppl), TPS217-TPS217, 2017 | 9 | 2017 |
| Updated results of a phase 1 study combining the matrix metalloproteinase 9 inhibitor GS-5745 and mFOLFOX6 in patients with advanced gastric/gastroesophageal junction cancer. MA Shah, A Starodub, J Berlin, CB Brachmann, X Huang, V Smith, ... Journal of Clinical Oncology 35 (4_suppl), 108-108, 2017 | 4 | 2017 |
| Updated results of a phase 1 study combining the matrix metalloproteinase 9 inhibitor GS-5745 with gemcitabine and nab-paclitaxel in patients with advanced pancreatic cancer. JC Bendell, MR Patel, CB Brachmann, X Huang, JD Maltzman, V Smith, ... Journal of Clinical Oncology 35 (4_suppl), 363-363, 2017 | 2 | 2017 |
| Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib Alone or in Combination with Idelalisib or Entospletinib in Patients with … AV Danilov, C Herbaux, MJS Dyer, P Hillmen, S Rule, EA Kio, X Huang, ... Blood 132, 3135, 2018 | 1 | 2018 |
| Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination with Idelalisib in Patients with B-Cell Lymphoma F Morschhauser, J Radford, L Ysebaert, SE Spurgeon, EA Kio, G Salles, ... Blood 132, 5345, 2018 | | 2018 |
| Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination with Entospletinib in Patients with B-Cell Lymphoma G Salles, MJS Dyer, DJ Hodson, K Bouabdallah, L Ysebaert, G Cartron, ... Blood 132, 5344, 2018 | | 2018 |
| Conformational sampling and non-dimer aggregates of HIV-1 protease containing darunavir promoted mutations L Pham, Z Liu, L Hu, X Huang, A Bhatt, K Bentz, T Tran, D Savin, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Results of a phase I study of GS-5745 in combination with gemcitabine and nab-paclitaxel in patients (pts) with advanced pancreatic cancer. JC Bendell, X Huang, V Smith, JD Maltzman, A Starodub Journal of Clinical Oncology 34 (15_suppl), e15683-e15683, 2016 | | 2016 |
