| 3, 5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel HS Sutherland, AST Tong, PJ Choi, A Blaser, D Conole, SG Franzblau, ... Bioorganic & medicinal chemistry 27 (7), 1292-1307, 2019 | 93 | 2019 |
| 6-Cyano analogues of bedaquiline as less lipophilic and potentially safer diarylquinolines for tuberculosis AST Tong, PJ Choi, A Blaser, HS Sutherland, SKY Tsang, J Guillemont, ... ACS medicinal chemistry letters 8 (10), 1019-1024, 2017 | 76 | 2017 |
| Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles HS Sutherland, AST Tong, PJ Choi, D Conole, A Blaser, SG Franzblau, ... Bioorganic & medicinal chemistry 26 (8), 1797-1809, 2018 | 73 | 2018 |
| Riociguat: first global approval D Conole, LJ Scott Drugs 73, 1967-1975, 2013 | 69 | 2013 |
| Colistimethate Sodium Dry Powder for Inhalation: A Review of Its Use in the Treatment of Chronic Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis D Conole, GM Keating Drugs 74, 377-387, 2014 | 63 | 2014 |
| Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline A Blaser, HS Sutherland, AST Tong, PJ Choi, D Conole, SG Franzblau, ... Bioorganic & Medicinal Chemistry 27 (7), 1283-1291, 2019 | 49 | 2019 |
| UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology M Mondal, D Conole, J Nautiyal, EW Tate British journal of cancer 126 (1), 24-33, 2022 | 41 | 2022 |
| Non-histone protein methylation: biological significance and bioengineering potential R Di Blasi, O Blyuss, JF Timms, D Conole, F Ceroni, HJ Whitwell ACS chemical biology 16 (2), 238-250, 2021 | 39 | 2021 |
| Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides D Conole, TM Beck, M Jay-Smith, MD Tingle, CT Eason, MA Brimble, ... Bioorganic & Medicinal Chemistry 22 (7), 2220-2235, 2014 | 34 | 2014 |
| Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer BM Simões, A Santiago-Gómez, C Chiodo, T Moreira, D Conole, S Lovell, ... Oncogene 39 (25), 4896-4908, 2020 | 31 | 2020 |
| Recent developments in cell permeable deubiquitinating enzyme activity-based probes D Conole, M Mondal, JD Majmudar, EW Tate Frontiers in Chemistry 7, 876, 2019 | 29 | 2019 |
| Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides D Rennison, D Conole, MD Tingle, J Yang, CT Eason, MA Brimble Bioorganic & medicinal chemistry letters 23 (24), 6629-6635, 2013 | 28 | 2013 |
| PROTACs, molecular glues and bifunctionals from bench to bedside: Unlocking the clinical potential of catalytic drugs M Maneiro, E De Vita, D Conole, CS Kounde, Q Zhang, EW Tate Progress in medicinal chemistry 60, 67-190, 2021 | 27 | 2021 |
| The maturation of DNA encoded libraries: opportunities for new users D Conole, J H Hunter, M J Waring Future Medicinal Chemistry 13 (2), 173-191, 2021 | 24 | 2021 |
| Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs) ED Vita Chemical Communications 58 (78), 10933-10936, 2022 | 23 | 2022 |
| Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis GL Lu, AST Tong, D Conole, HS Sutherland, PJ Choi, SG Franzblau, ... Bioorganic & medicinal chemistry 28 (22), 115784, 2020 | 19 | 2020 |
| Chemical instability and promiscuity of arylmethylidenepyrazolinone-based MDMX inhibitors J Stefaniak, AM Lewis, D Conole, SRG Galan, CJR Bataille, GM Wynne, ... ACS Chemical Biology 13 (10), 2849-2854, 2018 | 18 | 2018 |
| Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide D Rennison, O Laita, D Conole, M Jay-Smith, J Knauf, S Bova, M Cavalli, ... Bioorganic & medicinal chemistry 21 (18), 5886-5899, 2013 | 18 | 2013 |
| Discovery and mechanism of action studies of 4, 6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy A Vuorinen, IVL Wilkinson, M Chatzopoulou, B Edwards, SE Squire, ... European Journal of Medicinal Chemistry 220, 113431, 2021 | 15 | 2021 |
| Fatty Acid‐Derived Pro‐Toxicants of the Rat Selective Toxicant Norbormide H Choi, D Conole, DJ Atkinson, O Laita, M Jay‐Smith, MA Pagano, ... Chemistry & Biodiversity 13 (6), 762-775, 2016 | 15 | 2016 |
William A DennyDistinguished Professor, The University of Auckland在 auckland.ac.nz 的电子邮件经过验证
