Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application DM Floss, K Schallau, S Rose-John, U Conrad, J Scheller Trends in biotechnology 28 (1), 37-45, 2010 | 250 | 2010 |
Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding C Garbers, N Jänner, A Chalaris, ML Moss, DM Floss, D Meyer, ... Journal of Biological Chemistry 286 (17), 14804-14811, 2011 | 233 | 2011 |
Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview DM Floss, D Falkenburg, U Conrad Transgenic research 16, 315-332, 2007 | 164 | 2007 |
Insights into IL-23 biology: from structure to function DM Floss, J Schröder, M Franke, J Scheller Cytokine & growth factor reviews 26 (5), 569-578, 2015 | 152 | 2015 |
Biochemical and functional characterization of anti‐HIV antibody–ELP fusion proteins from transgenic plants DM Floss, M Sack, J Stadlmann, T Rademacher, J Scheller, E Stöger, ... Plant Biotechnology Journal 6 (4), 379-391, 2008 | 140 | 2008 |
ELPylated anti‐human TNF therapeutic single‐domain antibodies for prevention of lethal septic shock U Conrad, I Plagmann, S Malchow, M Sack, DM Floss, AA Kruglov, ... Plant biotechnology journal 9 (1), 22-31, 2011 | 129 | 2011 |
Influence of elastin‐like peptide fusions on the quantity and quality of a tobacco‐derived human immunodeficiency virus‐neutralizing antibody DM Floss, M Sack, E Arcalis, J Stadlmann, H Quendler, T Rademacher, ... Plant biotechnology journal 7 (9), 899-913, 2009 | 114 | 2009 |
IL‐6 trans‐signaling controls liver regeneration after partial hepatectomy N Fazel Modares, R Polz, F Haghighi, L Lamertz, K Behnke, Y Zhuang, ... Hepatology 70 (6), 2075-2091, 2019 | 112 | 2019 |
Expression and immunogenicity of the mycobacterial Ag85B/ESAT‐6 antigens produced in transgenic plants by elastin‐like peptide fusion strategy DM Floss, M Mockey, G Zanello, D Brosson, M Diogon, R Frutos, T Bruel, ... BioMed Research International 2010 (1), 274346, 2010 | 89 | 2010 |
Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor DM Floss, S Mrotzek, T Klöcker, J Schröder, J Grötzinger, S Rose-John, ... Journal of Biological Chemistry 288 (27), 19386-19400, 2013 | 76 | 2013 |
ELP ylated haemagglutinins produced in tobacco plants induce potentially neutralizing antibodies against H5N 1 viruses in mice HT Phan, J Pohl, DM Floss, F Rabenstein, J Veits, BT Le, HH Chu, ... Plant biotechnology journal 11 (5), 582-593, 2013 | 71 | 2013 |
Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses L Lamertz, F Rummel, R Polz, P Baran, S Hansen, GH Waetzig, JM Moll, ... Science signaling 11 (550), eaar7388, 2018 | 68 | 2018 |
A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1 R Geissler, A Simkin, D Floss, R Patel, EA Fogarty, J Scheller, A Grimson Genes & Development 30 (9), 1070-1085, 2016 | 67 | 2016 |
Interleukin-6, but not the interleukin-6 receptor plays a role in recovery from dextran sodium sulfate-induced colitis J Sommer, E Engelowski, P Baran, C Garbers, DM Floss, J Scheller International journal of molecular medicine 34 (3), 651-660, 2014 | 66 | 2014 |
Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases DM Floss, T Klöcker, J Schröder, L Lamertz, S Mrotzek, B Strobl, ... Molecular biology of the cell 27 (14), 2301-2316, 2016 | 61 | 2016 |
Synthetic cytokine receptors transmit biological signals using artificial ligands E Engelowski, A Schneider, M Franke, H Xu, R Clemen, A Lang, P Baran, ... Nature communications 9 (1), 2034, 2018 | 60 | 2018 |
Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10 J Sommer, C Garbers, J Wolf, A Trad, JM Moll, M Sack, R Fischer, ... Journal of Biological Chemistry 289 (32), 22140-22150, 2014 | 53 | 2014 |
IL-12 and IL-23—close relatives with structural homologies but distinct immunological functions DM Floss, JM Moll, J Scheller Cells 9 (10), 2184, 2020 | 52 | 2020 |
Non-canonical interleukin 23 receptor complex assembly: p40 protein recruits interleukin 12 receptor β1 via site II and induces p19/interleukin 23 receptor interaction via site III J Schröder, JM Moll, P Baran, J Grötzinger, J Scheller, DM Floss Journal of Biological Chemistry 290 (1), 359-370, 2015 | 52 | 2015 |
Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 … J Sommer, T Effenberger, E Volpi, GH Waetzig, M Bernhardt, J Suthaus, ... Journal of Biological Chemistry 287 (17), 13743-13751, 2012 | 47 | 2012 |