| Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis T Girbl, T Lenn, L Perez, L Rolas, A Barkaway, A Thiriot, C Del Fresno, ... Immunity 49 (6), 1062-1076. e6, 2018 | 297 | 2018 |
| Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis … C del Fresno, F García-Rio, V Gómez-Pina, A Soares-Schanoski, ... The Journal of Immunology 182 (10), 6494-6507, 2009 | 290 | 2009 |
| Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes V Gomez-Pina, A Soares-Schanoski, A Rodriguez-Rojas, C Del Fresno, ... The Journal of Immunology 179 (6), 4065-4073, 2007 | 257 | 2007 |
| Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients P Escoll, C del Fresno, L Garcı́a, G Vallés, MJ Lendı́nez, F Arnalich, ... Biochemical and biophysical research communications 311 (2), 465-472, 2003 | 233 | 2003 |
| Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences E López-Collazo, C Del Fresno Critical care 17, 1-11, 2013 | 226 | 2013 |
| Optimal generation of tissue-resident but not circulating memory T cells during viral infection requires crosspriming by DNGR-1+ dendritic cells S Iborra, M Martínez-López, SC Khouili, M Enamorado, FJ Cueto, ... Immunity 45 (4), 847-860, 2016 | 210 | 2016 |
| Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans C del Fresno, D Soulat, S Roth, K Blazek, I Udalova, D Sancho, J Ruland, ... Immunity 38 (6), 1176-1186, 2013 | 208 | 2013 |
| Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4 C Del Fresno, K Otero, L Gómez-García, MC González-León, ... The Journal of Immunology 174 (5), 3032-3040, 2005 | 181 | 2005 |
| Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance SK Biswas, P Bist, MK Dhillon, T Kajiji, C Del Fresno, M Yamamoto, ... The Journal of Immunology 179 (6), 4083-4092, 2007 | 149 | 2007 |
| p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation A Risco, C del Fresno, A Mambol, D Alsina-Beauchamp, KF MacKenzie, ... Proceedings of the National Academy of Sciences 109 (28), 11200-11205, 2012 | 143 | 2012 |
| Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism C del Fresno, V Gomez-Pina, V Lores, A Soares-Schanoski, ... PloS one 3 (7), e2667, 2008 | 117 | 2008 |
| Flexible signaling of myeloid C-type lectin receptors in immunity and inflammation C Del Fresno, S Iborra, P Saz-Leal, M Martínez-López, D Sancho Frontiers in immunology 9, 804, 2018 | 114 | 2018 |
| Leishmania uses mincle to target an inhibitory ITAM signaling pathway in dendritic cells that dampens adaptive immunity to infection S Iborra, M Martínez-López, FJ Cueto, R Conde-Garrosa, C Del Fresno, ... Immunity 45 (4), 788-801, 2016 | 98 | 2016 |
| DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment C Del Fresno, P Saz-Leal, M Enamorado, SK Wculek, S Martínez-Cano, ... Science 362 (6412), 351-356, 2018 | 88 | 2018 |
| Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes C del Fresno, L Soler-Rangel, A Soares-Schanoski, V Gómez-Piña, ... Journal of endotoxin research 13 (1), 39-52, 2007 | 86 | 2007 |
| Dectin-1/2–induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses MMM Kaisar, M Ritter, C Del Fresno, HS Jónasdóttir, AJ van der Ham, ... PLoS biology 16 (4), e2005504, 2018 | 85 | 2018 |
| SHIP-1 couples to the dectin-1 hemITAM and selectively modulates reactive oxygen species production in dendritic cells in response to Candida albicans N Blanco-Menéndez, C Del Fresno, S Fernandes, E Calvo, ... The Journal of Immunology 195 (9), 4466-4478, 2015 | 55 | 2015 |
| Monocytes as effector cells: Activated Ly‐6Chigh mouse monocytes migrate to the lymph nodes through the lymph and cross‐present antigens to CD8+ T cells P Leirião, C del Fresno, C Ardavín European journal of immunology 42 (8), 2042-2051, 2012 | 53 | 2012 |
| Translocated LPS might cause endotoxin tolerance in circulating monocytes of cystic fibrosis patients R Del Campo, E Martinez, C Del Fresno, R Alenda, V Gomez-Pina, ... PloS one 6 (12), e29577, 2011 | 50 | 2011 |
| Nitric oxide activates the expression of IRAK-M via the release of TNF-α in human monocytes C del Fresno, L Gómez-Garcı́a, L Caveda, P Escoll, F Arnalich, R Zamora, ... Nitric Oxide 10 (4), 213-220, 2004 | 39 | 2004 |
