| Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling Y Hiruma, C Sacristan, ST Pachis, A Adamopoulos, T Kuijt, M Ubbink, ... Science 348 (6240), 1264-1267, 2015 | 257 | 2015 |
| Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment PHJ Keizers, A Saragliadis, Y Hiruma, M Overhand, M Ubbink Journal of the American Chemical Society 130 (44), 14802-14812, 2008 | 199 | 2008 |
| The structure of the cytochrome P450cam–putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography Y Hiruma, MAS Hass, Y Kikui, WM Liu, B Ölmez, SP Skinner, A Blok, ... Journal of molecular biology 425 (22), 4353-4365, 2013 | 142 | 2013 |
| A solution model of the complex formed by adrenodoxin and adrenodoxin reductase determined by paramagnetic NMR spectroscopy PHJ Keizers, B Mersinli, W Reinle, J Donauer, Y Hiruma, F Hannemann, ... Biochemistry 49 (32), 6846-6855, 2010 | 68 | 2010 |
| Validation of a lanthanide tag for the analysis of protein dynamics by paramagnetic NMR spectroscopy MAS Hass, PHJ Keizers, A Blok, Y Hiruma, M Ubbink Journal of the American Chemical Society 132 (29), 9952-9953, 2010 | 62 | 2010 |
| Identification of productive and futile encounters in an electron transfer protein complex W Andrałojć, Y Hiruma, WM Liu, E Ravera, M Nojiri, G Parigi, C Luchinat, ... Proceedings of the National Academy of Sciences 114 (10), E1840-E1847, 2017 | 59 | 2017 |
| The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage C Wallin, Y Hiruma, SKTS Warmlander, I Huvent, J Jarvet, JP Abrahams, ... Journal of the American Chemical Society 140 (26), 8138-8146, 2018 | 56 | 2018 |
| Delicate conformational balance of the redox enzyme cytochrome P450cam SP Skinner, WM Liu, Y Hiruma, M Timmer, A Blok, MAS Hass, M Ubbink Proceedings of the National Academy of Sciences 112 (29), 9022-9027, 2015 | 46 | 2015 |
| Endogenous polyamines reduce the toxicity of soluble aβ peptide aggregates associated with Alzheimer’s disease J Luo, I Mohammed, SKTS Wärmländer, Y Hiruma, A Gräslund, ... Biomacromolecules 15 (6), 1985-1991, 2014 | 33 | 2014 |
| Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase Y Hiruma, A Koch, S Dharadhar, RP Joosten, A Perrakis Proteins: Structure, Function, and Bioinformatics 84 (12), 1761-1766, 2016 | 30 | 2016 |
| Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures Y Hiruma, A Koch, N Hazraty, F Tsakou, RH Medema, RP Joosten, ... Journal of Biological Chemistry 292 (35), 14496-14504, 2017 | 21 | 2017 |
| Hot‐Spot Residues in the Cytochrome P450cam–Putidaredoxin Binding Interface Y Hiruma, A Gupta, A Kloosterman, C Olijve, B Ölmez, MAS Hass, ... ChemBioChem 15 (1), 80-86, 2014 | 13 | 2014 |
| Interactions between N-terminal modules in MPS1 enable spindle checkpoint silencing ST Pachis, Y Hiruma, EC Tromer, A Perrakis, GJPL Kops Cell reports 26 (8), 2101-2112. e6, 2019 | 8 | 2019 |
| Modulation of protein–ligand interactions by photocleavage of a cyclic peptide using phosphatidylinositol 3‐kinase SH3 domain as model system I Takahashi, S Kuroiwa, HE Lindfors, LA Ndamba, Y Hiruma, T Yajima, ... Journal of Peptide Science: An Official Publication of the European Peptide …, 2009 | 5 | 2009 |
| A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop JC Roorda, RP Joosten, A Perrakis, Y Hiruma Proteins: Structure, Function, and Bioinformatics 87 (4), 348-352, 2019 | 3 | 2019 |
| LAHMA: structure analysis through local annotation of homology-matched amino acids B van Beusekom, G Damaskos, ML Hekkelman, F Salgado-Polo, ... Acta Crystallographica Section D: Structural Biology 77 (1), 28-40, 2021 | 2 | 2021 |
| Cover Picture: Hot‐Spot Residues in the Cytochrome P450cam–Putidaredoxin Binding Interface (ChemBioChem 1/2014) Y Hiruma, A Gupta, A Kloosterman, C Olijve, B Ölmez, MAS Hass, ... ChemBioChem 15 (1), 1-1, 2014 | 1 | 2014 |
| The MPS1 kinase NTE region has helical propensity and preferred conformations towards the TPR domain Y Hiruma, MT Matsoukas, WG Touw, G Spyroulias, GJPL Kops, M Ubbink, ... bioRxiv, 2020.03. 31.018036, 2020 | | 2020 |
| The Neuronal Tau Protein Blocks In Vitro Fibrillation of the Amyloid-β (Aβ) Peptide C Wallin, Y Hiruma, S Warmlander, I Huvent, J Jarvet, JP Abrahams, ... Biophysical Journal 116 (3), 306a, 2019 | | 2019 |
| MPS1 N-terminal domains interact to regulate kinetochores levels and normal mitotic progression. ST Pachis, Y Hiruma, M Ubbink, A Perrakis, GJ Kops MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
