| Development and evaluation of a generic physiologically based pharmacokinetic model for children AN Edginton, W Schmitt, S Willmann Clinical pharmacokinetics 45, 1013-1034, 2006 | 356 | 2006 |
| Applied concepts in PBPK modeling: how to build a PBPK/PD model L Kuepfer, C Niederalt, T Wendl, JF Schlender, S Willmann, J Lippert, ... CPT: pharmacometrics & systems pharmacology 5 (10), 516-531, 2016 | 326 | 2016 |
| A computational systems biology software platform for multiscale modeling and simulation: integrating whole-body physiology, disease biology, and molecular reaction networks T Eissing, L Kuepfer, C Becker, M Block, K Coboeken, T Gaub, L Goerlitz, ... Frontiers in physiology 2, 4, 2011 | 267 | 2011 |
| Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs S Willmann, K Höhn, A Edginton, M Sevestre, J Solodenko, W Weiss, ... Journal of pharmacokinetics and pharmacodynamics 34, 401-431, 2007 | 251 | 2007 |
| A physiological model for the estimation of the fraction dose absorbed in humans S Willmann, W Schmitt, J Keldenich, J Lippert, JB Dressman Journal of medicinal chemistry 47 (16), 4022-4031, 2004 | 247 | 2004 |
| A mechanistic approach for the scaling of clearance in children AN Edginton, W Schmitt, B Voith, S Willmann Clinical pharmacokinetics 45, 683-704, 2006 | 241 | 2006 |
| PK-Sim®: a physiologically based pharmacokinetic ‘whole-body’model S Willmann, J Lippert, M Sevestre, J Solodenko, F Fois, W Schmitt Biosilico 1 (4), 121-124, 2003 | 209 | 2003 |
| Physiology-based simulations of a pathological condition: prediction of pharmacokinetics in patients with liver cirrhosis AN Edginton, S Willmann Clinical pharmacokinetics 47, 743-752, 2008 | 193 | 2008 |
| Whole body physiologically-based pharmacokinetic models: their use in clinical drug development AN Edginton, FP Theil, W Schmitt, S Willmann Expert opinion on drug metabolism & toxicology 4 (9), 1143-1152, 2008 | 172 | 2008 |
| Risk to the breast‐fed neonate from codeine treatment to the mother: a quantitative mechanistic modeling study S Willmann, AN Edginton, K Coboeken, G Ahr, J Lippert Clinical Pharmacology & Therapeutics 86 (6), 634-643, 2009 | 154 | 2009 |
| Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, part 1: oral solutions K Thelen, K Coboeken, S Willmann, R Burghaus, JB Dressman, J Lippert Journal of pharmaceutical sciences 100 (12), 5324-5345, 2011 | 146 | 2011 |
| From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools S Willmann, J Lippert, W Schmitt Expert opinion on drug metabolism & toxicology 1 (1), 159-168, 2005 | 135 | 2005 |
| A physiologic model for simulating gastrointestinal flow and drug absorption in rats S Willmann, W Schmitt, J Keldenich, JB Dressman Pharmaceutical research 20, 1766-1771, 2003 | 126 | 2003 |
| Development of a whole-body physiologically based pharmacokinetic approach to assess the pharmacokinetics of drugs in elderly individuals JF Schlender, M Meyer, K Thelen, M Krauss, S Willmann, T Eissing, ... Clinical pharmacokinetics 55, 1573-1589, 2016 | 113 | 2016 |
| Inhalation of a dry powder ciprofloxacin formulation in healthy subjects: a phase I study H Stass, J Nagelschmitz, S Willmann, H Delesen, A Gupta, S Baumann Clinical drug investigation 33, 419-427, 2013 | 108 | 2013 |
| Gestation-specific changes in the anatomy and physiology of healthy pregnant women: an extended repository of model parameters for physiologically based pharmacokinetic … A Dallmann, I Ince, M Meyer, S Willmann, T Eissing, G Hempel Clinical pharmacokinetics 56, 1303-1330, 2017 | 106 | 2017 |
| A generic integrated physiologically based whole‐body model of the glucose‐insulin‐glucagon regulatory system S Schaller, S Willmann, J Lippert, L Schaupp, TR Pieber, A Schuppert, ... CPT: pharmacometrics & systems pharmacology 2 (8), 1-10, 2013 | 85 | 2013 |
| Development of a paediatric population-based model of the pharmacokinetics of rivaroxaban S Willmann, C Becker, R Burghaus, K Coboeken, A Edginton, J Lippert, ... Clinical pharmacokinetics 53, 89-102, 2014 | 82 | 2014 |
| Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, part II: extension to describe performance of solid … K Thelen, K Coboeken, S Willmann, JB Dressman, J Lippert Journal of pharmaceutical sciences 101 (3), 1267-1280, 2012 | 81 | 2012 |
| A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim C Niederalt, L Kuepfer, J Solodenko, T Eissing, HU Siegmund, M Block, ... Journal of pharmacokinetics and pharmacodynamics 45, 235-257, 2018 | 80 | 2018 |
Jörg LippertBayer AG在 bayer.com 的电子邮件经过验证
