Current best practices in single‐cell RNA‐seq analysis: a tutorial MD Luecken, FJ Theis Molecular systems biology 15 (6), e8746, 2019 | 1652 | 2019 |
Benchmarking atlas-level data integration in single-cell genomics MD Luecken, M Büttner, K Chaichoompu, A Danese, M Interlandi, ... Nature methods 19 (1), 41-50, 2022 | 586 | 2022 |
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ... Nature medicine 27 (3), 546-559, 2021 | 560* | 2021 |
Mapping single-cell data to reference atlases by transfer learning M Lotfollahi, M Naghipourfar, MD Luecken, M Khajavi, M Büttner, ... Nature biotechnology 40 (1), 121-130, 2022 | 333* | 2022 |
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis D Wendisch, O Dietrich, T Mari, S von Stillfried, IL Ibarra, M Mittermaier, ... Cell 184 (26), 6243-6261. e27, 2021 | 320 | 2021 |
Best practices for single-cell analysis across modalities L Heumos, AC Schaar, C Lance, A Litinetskaya, F Drost, L Zappia, ... Nature Reviews Genetics 24 (8), 550-572, 2023 | 263 | 2023 |
An integrated cell atlas of the lung in health and disease L Sikkema, C Ramírez-Suástegui, DC Strobl, TE Gillett, L Zappia, ... Nature Medicine 29 (6), 1563-1577, 2023 | 226* | 2023 |
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice A Aliluev, S Tritschler, M Sterr, L Oppenländer, J Hinterdobler, T Greisle, ... Nature metabolism 3 (9), 1202-1216, 2021 | 69 | 2021 |
A sandbox for prediction and integration of DNA, RNA, and proteins in single cells MD Luecken, DB Burkhardt, R Cannoodt, C Lance, A Agrawal, H Aliee, ... Thirty-fifth conference on neural information processing systems datasets …, 2021 | 69 | 2021 |
The scverse project provides a computational ecosystem for single-cell omics data analysis I Virshup, D Bredikhin, L Heumos, G Palla, G Sturm, A Gayoso, I Kats, ... Nature biotechnology 41 (5), 604-606, 2023 | 67 | 2023 |
Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2 JP Lopez, MD Lücken, E Brivio, S Karamihalev, A Kos, C De Donno, ... Neuron 110 (14), 2283-2298. e9, 2022 | 50 | 2022 |
Multimodal single cell data integration challenge: results and lessons learned C Lance, MD Luecken, DB Burkhardt, R Cannoodt, P Rautenstrauch, ... BioRxiv, 2022.04. 11.487796, 2022 | 49 | 2022 |
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons J Giehrl‐Schwab, F Giesert, B Rauser, CL Lao, S Hembach, S Lefort, ... EMBO molecular medicine 14 (5), e14797, 2022 | 36 | 2022 |
Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation K Baßler, W Fujii, TS Kapellos, E Dudkin, N Reusch, A Horne, B Reiz, ... Frontiers in immunology 13, 917232, 2022 | 30* | 2022 |
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease S Schmidt, MD Luecken, D Trümbach, S Hembach, KM Niedermeier, ... Nature communications 13 (1), 4819, 2022 | 20 | 2022 |
The discovAIR project: a roadmap towards the Human Lung Cell Atlas MD Luecken, LE Zaragosi, E Madissoon, L Sikkema, AB Firsova, ... European Respiratory Journal 60 (2), 2022 | 18 | 2022 |
Optimizing Xenium In Situ data utility by quality assessment and best practice analysis workflows SM Salas, P Czarnewski, LB Kuemmerle, S Helgadottir, ... BioRxiv, 2023.02. 13.528102, 2023 | 17 | 2023 |
RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells A Subramanian, KA Vernon, M Slyper, J Waldman, MD Luecken, K Gosik, ... bioRxiv, 2020.06. 23.167098, 2020 | 15 | 2020 |
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis NJ Lang, J Gote-Schniering, D Porras-Gonzalez, L Yang, LJ De Sadeleer, ... Science translational medicine 15 (725), eadh0908, 2023 | 13 | 2023 |
Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage K Lutz, A Musumeci, C Sie, E Dursun, E Winheim, J Bagnoli, ... Nature communications 13 (1), 3456, 2022 | 13 | 2022 |