Human airway organoid engineering as a step toward lung regeneration and disease modeling Q Tan, KM Choi, D Sicard, DJ Tschumperlin Biomaterials 113, 118-132, 2017 | 192 | 2017 |
P300 acetyltransferase mediates stiffness-induced activation of hepatic stellate cells into tumor-promoting myofibroblasts C Dou, Z Liu, K Tu, H Zhang, C Chen, U Yaqoob, Y Wang, J Wen, ... Gastroenterology 154 (8), 2209-2221. e14, 2018 | 167 | 2018 |
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis AJ Haak, E Kostallari, D Sicard, G Ligresti, KM Choi, N Caporarello, ... Science translational medicine 11 (516), 2019 | 163 | 2019 |
Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis G Tjin, ES White, A Faiz, D Sicard, DJ Tschumperlin, A Mahar, EPW Kable, ... Disease models & mechanisms 10 (11), 1301-1312, 2017 | 143 | 2017 |
Correction: Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis (doi: 10.1242/dmm. 030114) G Tjin, ES White, A Faiz, D Sicard, DJ Tschumperlin, A Mahar, EPW Kable, ... | 143* | 2017 |
Aging and anatomical variations in lung tissue stiffness D Sicard, AJ Haak, KM Choi, AR Craig, LE Fredenburgh, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (6 …, 2018 | 140 | 2018 |
TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression AJ Jorgenson, KM Choi, D Sicard, KMJ Smith, SE Hiemer, X Varelas, ... American Journal of Physiology-Cell Physiology 312 (3), C277-C285, 2017 | 88 | 2017 |
Matrix stiffness-modulated proliferation and secretory function of the airway smooth muscle cells A Shkumatov, M Thompson, KM Choi, D Sicard, K Baek, DH Kim, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 …, 2015 | 86 | 2015 |
AFM investigation of Pseudomonas aeruginosa lectin LecA (PA-IL) filaments induced by multivalent glycoclusters D Sicard, S Cecioni, M Iazykov, Y Chevolot, SE Matthews, JP Praly, ... Chemical Communications 47 (33), 9483-9485, 2011 | 78 | 2011 |
Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension F Liu, CM Haeger, PB Dieffenbach, D Sicard, I Chrobak, AMF Coronata, ... JCI insight 1 (8), 2016 | 74 | 2016 |
Measured pulmonary arterial tissue stiffness is highly sensitive to AFM indenter dimensions D Sicard, LE Fredenburgh, DJ Tschumperlin Journal of the mechanical behavior of biomedical materials 74, 118-127, 2017 | 60 | 2017 |
Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents M Deng, J Lin, S Nowsheen, T Liu, Y Zhao, PW Villalta, D Sicard, ... Science advances 6 (37), eabb2630, 2020 | 50 | 2020 |
Nascent lung organoids reveal epithelium-and bone morphogenetic protein–mediated suppression of fibroblast activation Q Tan, XY Ma, W Liu, JA Meridew, DL Jones, AJ Haak, D Sicard, ... American journal of respiratory cell and molecular biology 61 (5), 607-619, 2019 | 43 | 2019 |
Spinal cord injury results in chronic mechanical stiffening JG Cooper, D Sicard, S Sharma, S Van Gulden, TL McGuire, MP Cajiao, ... Journal of neurotrauma 37 (3), 494-506, 2020 | 31 | 2020 |
Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis E Kostallari, B Wei, D Sicard, J Li, SA Cooper, J Gao, M Dehankar, Y Li, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 322 (2 …, 2022 | 24 | 2022 |
Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis JC Horowitz, DJ Tschumperlin, KK Kim, JJ Osterholzer, N Subbotina, ... Thrombosis and haemostasis 119 (12), 1968-1980, 2019 | 22 | 2019 |
YAP/TAZ are Activated by Mechanical and Hormonal Stimuli in Myometrium and Exhibit Increased Baseline Activation in Uterine Fibroids MKP Purdy, M Ducharme, AJ Haak, J Ravix, Q Tan, D Sicard, YS Prakash, ... Reproductive Sciences, 1-12, 2020 | 18 | 2020 |
Dopamine D1 receptor stimulates cathepsin K-dependent degradation and resorption of collagen I in lung fibroblasts AM Diaz Espinosa, PA Link, D Sicard, I Jorba, DJ Tschumperlin, AJ Haak Journal of cell science 133 (23), jcs248278, 2020 | 16 | 2020 |
Molecular arrangement between multivalent glycocluster and Pseudomonas aeruginosa LecA (PA‐IL) by atomic force microscopy: influence of the glycocluster … D Sicard, Y Chevolot, E Souteyrand, A Imberty, S Vidal, ... Journal of Molecular Recognition 26 (12), 694-699, 2013 | 15 | 2013 |
Reduced SPAG17 expression in systemic sclerosis triggers myofibroblast transition and drives fibrosis P Sapao, EDO Roberson, B Shi, S Assassi, B Skaug, F Lee, A Naba, ... Journal of Investigative Dermatology, 2022 | 7 | 2022 |