Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration DV Neel, H Basu, G Gunner, MD Bergstresser, RM Giadone, H Chung, ... Neuron 111 (8), 1222-1240. e9, 2023 | 49 | 2023 |
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types M Ximerakis, KM Holton, RM Giadone, C Ozek, M Saxena, S Santiago, ... Nature Aging 3 (3), 327-345, 2023 | 36 | 2023 |
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics RM Giadone, JD Rosarda, PR Akepati, AC Thomas, B Boldbaatar, ... Amyloid 25 (3), 148-155, 2018 | 16 | 2018 |
Rapid implementation of a SARS-CoV-2 diagnostic quantitative real-time PCR test with emergency use authorization at a large academic safety net hospital K Vanuytsel, A Mithal, RM Giadone, AK Yeung, TM Matte, TW Dowrey, ... Med 1 (1), 152-157. e3, 2020 | 15 | 2020 |
Expression of amyloidogenic transthyretin drives hepatic proteostasis remodeling in an induced pluripotent stem cell model of systemic amyloid disease RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia, ... Stem Cell Reports 15 (2), 515-528, 2020 | 13 | 2020 |
Expression levels of lamin A or C are critical to nuclear maturation, functional responses, and gene expression profiles in differentiating mouse neutrophils K Szymczak, MGH Pelletier, K Malu, AM Barbeau, RM Giadone, ... ImmunoHorizons 6 (1), 16-35, 2022 | 6 | 2022 |
qRT-PCR Platforms for Diagnosing and Reporting SARS-CoV-2 Infection in Human Samples RM Giadone, A Mithal, GJ Miller, TM Matte, AK Yeung, TW Dowrey, ... STAR protocols 1 (2), 100102, 2020 | 4 | 2020 |
Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy DMK Leow, YK Ng, LC Wang, HWL Koh, T Zhao, ZJ Khong, T Tabaglio, ... The Journal of Clinical Investigation 134 (12), 2024 | 2 | 2024 |
Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition CV Edwards, GM Ferri, J Villegas-Galaviz, S Ghosh, PS Bawa, F Wang, ... bioRxiv, 2024.03. 14.584987, 2024 | 2 | 2024 |
Mapping cellular response to destabilized transthyretin reveals cell-and amyloidogenic protein-specific signatures S Ghosh, C Villacorta-Martin, J Lindstrom-Vautrin, D Kenney, CS Golden, ... Amyloid 30 (4), 379-393, 2023 | 2 | 2023 |
A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring TW Dowrey, SF Cranston, N Skvir, Y Lok, B Gould, B Petrowitz, D Villar, ... Aging Cell, e14351, 2024 | 1 | 2024 |
A Workflow Guide to RNA-Seq Analysis of Chaperone Function and Beyond KM Holton, RM Giadone, BJ Lang, SK Calderwood Chaperones: Methods and Protocols, 39-60, 2023 | 1 | 2023 |
Patient-specific induced pluripotent stem cells for understanding and assessing novel therapeutics for multisystem transthyretin amyloid disease RM Giadone, S Ghosh, GJ Murphy Novel concepts in iPSC disease modeling, 105-122, 2022 | 1 | 2022 |
Studies of murine neutrophil and macrophage progenitors with ectopic A-type lamins or Sun2 expression implicate the importance of nuclear envelope proteins in myelopoiesis MGH Pelletier, K Malu, SC Babroudi, RM Giadone, P Gaines Blood 124 (21), 1401, 2014 | 1 | 2014 |
Identifying critical roles for the lamin B receptor and additional nuclear envelope proteins in regulating the proliferation and differentiation of myeloid progenitors KM Malu, HP Shah, MGH Pelletier, RM Giadone, KL Gendreau, ... | 1 | 2013 |
Author Correction: Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types M Ximerakis, KM Holton, RM Giadone, C Ozek, M Saxena, S Santiago, ... Nature Aging, 1-1, 2025 | | 2025 |
Additional Cover TW Dowrey, SF Cranston, N Skvir, Y Lok, B Gould, B Petrowitz, D Villar, ... Aging Cell 24 (1), e14479, 2025 | | 2025 |
Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets ME Watts, RM Giadone, A Ordureau, KM Holton, JW Harper, LL Rubin Frontiers in Cellular Neuroscience 17, 1327361, 2024 | | 2024 |
Abnormal Global Longitudinal Strain Correlates with Amyloidogenic Light Chain-Induced Cardiac Dysfunction via Direct Myocardial Toxicity in Patients without Significant Amyloid … GM Ferri, J Villegas Galaviz, T Ajayi, R Giadone, GJ Murphy, A Staron, ... Blood 142 (Supplement 1), 3415-3415, 2023 | | 2023 |
Mapping and Modelling the Molecular Mechanisms That Drive Clonal Plasma Cell-Derived Amyloidogenic Light Chain Induced Cardiotoxicity CV Edwards, R Giadone, S Ghosh, G Morgan, V Sanchorawala, ... Blood 140 (Supplement 1), 7127-7128, 2022 | | 2022 |