Aminoacyl-tRNA synthesis and translational quality control J Ling, N Reynolds, M Ibba Annual review of microbiology 63, 61-78, 2009 | 444 | 2009 |
Exome sequencing and the management of neurometabolic disorders M Tarailo-Graovac, C Shyr, CJ Ross, GA Horvath, R Salvarinova, XC Ye, ... New England Journal of Medicine 374 (23), 2246-2255, 2016 | 313 | 2016 |
Severe oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site J Ling, D Söll Proceedings of the National Academy of Sciences 107 (9), 4028-4033, 2010 | 259 | 2010 |
Post-transfer editing in vitro and in vivo by the β subunit of phenylalanyl-tRNA synthetase H Roy, J Ling, M Irnov, M Ibba The EMBO journal 23 (23), 4639-4648, 2004 | 192 | 2004 |
Upgrading protein synthesis for synthetic biology P O'donoghue, J Ling, YS Wang, D Söll Nature chemical biology 9 (10), 594-598, 2013 | 181 | 2013 |
Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures X Zhang, J Ling, G Barcia, L Jing, J Wu, BJ Barry, GH Mochida, RS Hill, ... The American Journal of Human Genetics 94 (4), 547-558, 2014 | 152 | 2014 |
Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology J Ling, P O'donoghue, D Söll Nature Reviews Microbiology 13 (11), 707-721, 2015 | 131 | 2015 |
Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger J Ling, C Cho, LT Guo, HR Aerni, J Rinehart, D Söll Molecular cell 48 (5), 713-722, 2012 | 129 | 2012 |
Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase H Roy, J Ling, J Alfonzo, M Ibba Journal of Biological Chemistry 280 (46), 38186-38192, 2005 | 129 | 2005 |
Resampling and editing of mischarged tRNA prior to translation elongation J Ling, BR So, SS Yadavalli, H Roy, S Shoji, K Fredrick, K Musier-Forsyth, ... Molecular cell 33 (5), 654-660, 2009 | 123 | 2009 |
Mechanism of tRNA-dependent editing in translational quality control J Ling, H Roy, M Ibba Proceedings of the National Academy of Sciences 104 (1), 72, 2007 | 104 | 2007 |
Cell-specific differences in the requirements for translation quality control NM Reynolds, J Ling, H Roy, R Banerjee, SE Repasky, P Hamel, M Ibba Proceedings of the National Academy of Sciences 107 (9), 4063-4068, 2010 | 97 | 2010 |
Protein mistranslation protects bacteria against oxidative stress Y Fan, J Wu, MH Ung, N De Lay, C Cheng, J Ling Nucleic acids research 43 (3), 1740-1748, 2015 | 96 | 2015 |
Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNAPyl for genetic code expansion P O’Donoghue, L Prat, IU Heinemann, J Ling, K Odoi, WR Liu, D Söll FEBS letters 586 (21), 3931-3937, 2012 | 95 | 2012 |
Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine J Ling, SS Yadavalli, M Ibba Rna 13 (11), 1881-1886, 2007 | 75 | 2007 |
Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers Z Zhang, Y Ye, J Gong, H Ruan, CJ Liu, Y Xiang, C Cai, AY Guo, J Ling, ... Communications Biology 1 (1), 234, 2018 | 73 | 2018 |
Deficient activity of alanyl‐tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy T Nakayama, J Wu, P Galvin‐Parton, J Weiss, MR Andriola, RS Hill, ... Human mutation 38 (10), 1348-1354, 2017 | 69 | 2017 |
Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome J Ling, H Roy, D Qin, MAT Rubio, JD Alfonzo, K Fredrick, M Ibba Proceedings of the National Academy of Sciences 104 (39), 15299-15304, 2007 | 56 | 2007 |
Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase J Wu, Y Fan, J Ling Nucleic acids research 42 (10), 6523-6531, 2014 | 51 | 2014 |
Heterogeneity of stop codon readthrough in single bacterial cells and implications for population fitness Y Fan, CR Evans, KW Barber, K Banerjee, KJ Weiss, W Margolin, ... Molecular cell 67 (5), 826-836. e5, 2017 | 50 | 2017 |