Lipid landscapes and pipelines in membrane homeostasis JCM Holthuis, AK Menon Nature 510 (7503), 48-57, 2014 | 839 | 2014 |
Identification of a family of animal sphingomyelin synthases K Huitema, J Van Den Dikkenberg, JFHM Brouwers, JCM Holthuis The EMBO journal 23 (1), 33-44, 2004 | 687 | 2004 |
Lipid traffic: floppy drives and a superhighway J Holthuis, TP Levine Nature reviews molecular cell biology 6 (3), 209-220, 2005 | 628 | 2005 |
Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis T Pomorski, R Lombardi, H Riezman, PF Devaux, G van Meer, ... Molecular biology of the cell 14 (3), 1240-1254, 2003 | 432 | 2003 |
The organizing potential of sphingolipids in intracellular membrane transport JCM Holthuis, T Pomorski, RJ Raggers, H Sprong, G Van Meer Physiological reviews 81 (4), 1689-1723, 2001 | 417 | 2001 |
The multigenic sphingomyelin synthase family FG Tafesse, P Ternes, JCM Holthuis Journal of Biological Chemistry 281 (40), 29421-29425, 2006 | 336 | 2006 |
Two syntaxin homologues in the TGN/endosomal system of yeast JCM Holthuis, BJ Nichols, S Dhruvakumar, HRB Pelham The EMBO Journal, 1998 | 288 | 1998 |
Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells FG Tafesse, K Huitema, M Hermansson, S van der Poel, ... Journal of Biological Chemistry 282 (24), 17537-17547, 2007 | 255 | 2007 |
Tracking down lipid flippases and their biological functions T Pomorski, JCM Holthuis, A Herrmann, G van Meer Journal of cell science 117 (6), 805-813, 2004 | 232 | 2004 |
Sphingolipid transport in eukaryotic cells G Van Meer, JCM Holthuis Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000 | 215 | 2000 |
Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER AM Vacaru, FG Tafesse, P Ternes, V Kondylis, M Hermansson, ... Journal of Cell Biology 185 (6), 1013-1027, 2009 | 175 | 2009 |
Ceramides bind VDAC2 to trigger mitochondrial apoptosis S Dadsena, S Bockelmann, JGM Mina, DG Hassan, S Korneev, ... Nature communications 10 (1), 1832, 2019 | 172 | 2019 |
Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles N Alder-Baerens, Q Lisman, L Luong, T Pomorski, JCM Holthuis Molecular biology of the cell 17 (4), 1632-1642, 2006 | 171 | 2006 |
CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery S Bryde, H Hennrich, PM Verhulst, PF Devaux, G Lenoir, JCM Holthuis Journal of Biological Chemistry 285 (52), 40562-40572, 2010 | 155 | 2010 |
Cdc50p Plays a Vital Role in the ATPase Reaction Cycle of the Putative Aminophospholipid Transporter Drs2p*♦ G Lenoir, P Williamson, CF Puts, JCM Holthuis Journal of biological chemistry 284 (27), 17956-17967, 2009 | 153 | 2009 |
Lipid traffic: the ABC of transbilayer movement RJ Raggers, T Pomorski, JCM Holthuis, N Kälin, G van Meer Traffic 1 (3), 226-234, 2000 | 150 | 2000 |
Lipid microdomains, lipid translocation and the organization of intracellular membrane transport JCM Holthuis, G van Meer, K Huitema Molecular Membrane Biology 20 (3), 231-241, 2003 | 142 | 2003 |
In vivo profiling and visualization of cellular protein–lipid interactions using bifunctional fatty acids P Haberkant, R Raijmakers, M Wildwater, T Sachsenheimer, B Brügger, ... Angewandte Chemie International Edition 52 (14), 4033-4038, 2013 | 141 | 2013 |
The syntaxin Tlg1p mediates trafficking of chitin synthase III to polarized growth sites in yeast JCM Holthuis, BJ Nichols, HRB Pelham Molecular Biology of the Cell 9 (12), 3383-3397, 1998 | 137 | 1998 |
Tumor cells exhibit deregulation of the cell cycle histone gene promoter factor HiNF-D J Holthuis, TA Owen, AJ Van Wijnen, KL Wright, A Ramsey-Ewing, ... Science 247 (4949), 1454-1457, 1990 | 132 | 1990 |