| A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou, CA Gifford, ... Science 312 (5779), 1526-1530, 2006 | 1247 | 2006 |
| Clostridium difficile spore biology: sporulation, germination, and spore structural proteins D Paredes-Sabja, A Shen, JA Sorg Trends in microbiology 22 (7), 406-416, 2014 | 520 | 2014 |
| Global Analysis of the Sporulation Pathway of Clostridium difficile KA Fimlaid, JP Bond, KC Schutz, EE Putnam, JM Leung, TD Lawley, ... PLoS genetics 9 (8), e1003660, 2013 | 224 | 2013 |
| Synthetic riboswitches that induce gene expression in diverse bacterial species S Topp, CMK Reynoso, JC Seeliger, IS Goldlust, SK Desai, D Murat, ... Applied and environmental microbiology 76 (23), 7881-7884, 2010 | 210 | 2010 |
| Clostridium difficile Toxins: Mediators of Inflammation A Shen Journal of innate immunity 4 (2), 149-158, 2012 | 209 | 2012 |
| A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression A Shen, HD Kamp, A Gründling, DE Higgins Genes & Development 20 (23), 3283-3295, 2006 | 145 | 2006 |
| Diverse mechanisms regulate sporulation sigma factor activity in the Firmicutes KA Fimlaid, A Shen Current opinion in microbiology 24, 88-95, 2015 | 143 | 2015 |
| The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes A Shen, DE Higgins PLoS pathogens 2 (4), e30, 2006 | 140 | 2006 |
| SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins EE Putnam, AM Nock, TD Lawley, A Shen Journal of bacteriology 195 (6), 1214-1225, 2013 | 138 | 2013 |
| Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain PJ Lupardus, A Shen, M Bogyo, KC Garcia science 322 (5899), 265-268, 2008 | 137 | 2008 |
| A small-molecule antivirulence agent for treating Clostridium difficile infection KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ... Science translational medicine 7 (306), 306ra148-306ra148, 2015 | 134 | 2015 |
| The 5′ untranslated region‐mediated enhancement of intracellular listeriolysin O production is required for Listeria monocytogenes pathogenicity A Shen, DE Higgins Molecular microbiology 57 (5), 1460-1473, 2005 | 129 | 2005 |
| Structural and Functional Analysis of the CspB Protease Required for Clostridium Spore Germination CM Adams, BE Eckenroth, EE Putnam, S Doublié, A Shen PLoS Pathogens 9 (2), e1003165, 2013 | 126 | 2013 |
| Simplified, enhanced protein purification using an inducible, autoprocessing enzyme tag A Shen, PJ Lupardus, M Morell, EL Ponder, AM Sadaghiani, KC Garcia, ... PloS one 4 (12), e8119, 2009 | 112 | 2009 |
| Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins A Shen, PJ Lupardus, MM Gersch, AW Puri, VE Albrow, KC Garcia, ... Nature structural & molecular biology 18 (3), 364-371, 2011 | 93 | 2011 |
| Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin A Shen, PJ Lupardus, VE Albrow, A Guzzetta, JC Powers, KC Garcia, ... Nature chemical biology 5 (7), 469-478, 2009 | 92 | 2009 |
| Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis PH Oliveira, JW Ribis, EM Garrett, D Trzilova, A Kim, O Sekulovic, ... Nature microbiology 5 (1), 166-180, 2020 | 88 | 2020 |
| Sporulation and germination in clostridial pathogens A Shen, AN Edwards, MR Sarker, D Paredes-Sabja Microbiology spectrum 7 (6), 10.1128/microbiolspec. gpp3-0017-2018, 2019 | 86 | 2019 |
| Characterization of the dynamic germination of individual Clostridium difficile spores using Raman spectroscopy and differential interference contrast microscopy S Wang, A Shen, P Setlow, Y Li Journal of Bacteriology 197 (14), 2361-2373, 2015 | 83 | 2015 |
| Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB AW Puri, PJ Lupardus, E Deu, VE Albrow, KC Garcia, M Bogyo, A Shen Chemistry & biology 17 (11), 1201-1211, 2010 | 80 | 2010 |
