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NAN WANG
NAN WANG
在 mednet.ucla.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
P Langfelder, JP Cantle, D Chatzopoulou, N Wang, F Gao, I Al-Ramahi, ...
Nature neuroscience 19 (4), 623-633, 2016
3792016
Elevated TREM2 gene dosage reprograms microglia responsivity and ameliorates pathological phenotypes in Alzheimer’s disease models
CYD Lee, A Daggett, X Gu, LL Jiang, P Langfelder, X Li, N Wang, Y Zhao, ...
Neuron 97 (5), 1032-1048. e5, 2018
3602018
Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control
RG Yau, K Doerner, ER Castellanos, DL Haakonsen, A Werner, N Wang, ...
Cell 171 (4), 918-933. e20, 2017
3102017
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease
N Wang, M Gray, XH Lu, JP Cantle, SM Holley, E Greiner, X Gu, ...
Nature medicine 20 (5), 536-541, 2014
2102014
An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice
B Wilburn, DD Rudnicki, J Zhao, TM Weitz, Y Cheng, X Gu, E Greiner, ...
Neuron 70 (3), 427-440, 2011
1582011
Universal DNA methylation age across mammalian tissues
AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ...
Nature aging 3 (9), 1144-1166, 2023
1532023
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington’s disease
XH Lu, VB Mattis, N Wang, I Al-Ramahi, N van den Berg, SA Fratantoni, ...
Science translational medicine 6 (268), 268ra178-268ra178, 2014
1402014
Universal DNA methylation age across mammalian tissues
AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ...
BioRxiv, 2021.01. 18.426733, 2021
1042021
DNA methylation networks underlying mammalian traits
A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu, J Ablaeva, ...
Science 381 (6658), eabq5693, 2023
662023
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
AT Lu, P Narayan, MJ Grant, P Langfelder, N Wang, S Kwak, H Wilkinson, ...
Nature communications 11 (1), 4529, 2020
632020
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
VJ Sugrue, JA Zoller, P Narayan, AT Lu, OJ Ortega-Recalde, MJ Grant, ...
Elife 10, e64932, 2021
612021
MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice
P Langfelder, F Gao, N Wang, D Howland, S Kwak, TF Vogt, JS Aaronson, ...
PloS one 13 (1), e0190550, 2018
522018
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
X Gu, J Richman, P Langfelder, N Wang, S Zhang, M Bañez-Coronel, ...
Neuron 110 (7), 1173-1192. e7, 2022
362022
m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
Y Sun, H Dai, X Dai, J Yin, Y Cui, X Liu, G Gonzalez, J Yuan, F Tang, ...
Nature 623 (7987), 580-587, 2023
252023
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s disease
S Picó, A Parras, M Santos-Galindo, J Pose-Utrilla, M Castro, E Fraga, ...
Science Translational Medicine 13 (613), eabe7104, 2021
232021
Epigenetic predictors of maximum lifespan and other life history traits in mammals
CZ Li, A Haghani, TR Robeck, D Villar, AT Lu, J Zhang, CG Faulkes, H Vu, ...
BioRxiv, 2021.05. 16.444078, 2021
192021
Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington’s disease patients
CYD Lee, N Wang, K Shen, M Stricos, P Langfelder, KH Cheon, ...
Scientific Reports 10 (1), 20295, 2020
162020
An independent study of the preclinical efficacy of C2-8 in the R6/2 transgenic mouse model of Huntington's disease
N Wang, XH Lu, SV Sandoval, XW Yang
Journal of Huntington's disease 2 (4), 443-451, 2013
152013
Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures
N Wang, P Langfelder, M Stricos, L Ramanathan, JB Richman, R Vaca, ...
Neuron 110 (20), 3318-3338. e9, 2022
112022
Huntington disease’s glial progenitor cells hit the pause button in the mouse brain
N Wang, XW Yang
Cell Stem Cell 24 (1), 3-4, 2019
82019
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