Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia P Jaako, J Flygare, K Olsson, R Quere, M Ehinger, A Henson, S Ellis, ... Blood, The Journal of the American Society of Hematology 118 (23), 6087-6096, 2011 | 148 | 2011 |
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia P Jaako, S Debnath, K Olsson, D Bryder, J Flygare, S Karlsson Blood, The Journal of the American Society of Hematology 120 (11), 2225-2228, 2012 | 93 | 2012 |
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture S Singbrant, G Karlsson, M Ehinger, K Olsson, P Jaako, K Miharada, ... Blood, The Journal of the American Society of Hematology 115 (23), 4689-4698, 2010 | 70 | 2010 |
Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation A Ugale, GL Norddahl, M Wahlestedt, P Säwén, P Jaako, CJ Pronk, ... Cell reports 9 (4), 1246-1255, 2014 | 66 | 2014 |
EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome S Tan, L Kermasson, A Hoslin, P Jaako, A Faille, A Acevedo-Arozena, ... Blood, The Journal of the American Society of Hematology 134 (3), 277-290, 2019 | 56 | 2019 |
Disruption of the 5S RNP–Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia P Jaako, S Debnath, K Olsson, Y Zhang, J Flygare, MS Lindström, ... Leukemia 29 (11), 2221-2229, 2015 | 43 | 2015 |
Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia P Jaako, S Debnath, K Olsson, U Modlich, M Rothe, A Schambach, ... Haematologica 99 (12), 1792, 2014 | 39 | 2014 |
eIF6 rebinding dynamically couples ribosome maturation and translation P Jaako, A Faille, S Tan, CC Wong, N Escudero-Urquijo, ... Nature Communications 13 (1), 1562, 2022 | 32 | 2022 |
Lentiviral vectors with cellular promoters correct anemia and lethal bone marrow failure in a mouse model for Diamond-Blackfan anemia S Debnath, P Jaako, K Siva, M Rothe, J Chen, M Dahl, HB Gaspar, ... Molecular Therapy 25 (8), 1805-1814, 2017 | 30 | 2017 |
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond–Blackfan anaemia SE Sjögren, K Siva, S Soneji, AJ George, M Winkler, P Jaako, ... British Journal of Haematology 171 (4), 517-529, 2015 | 25 | 2015 |
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome K Siva, P Jaako, K Miharada, E Rörby, M Ehinger, G Karlsson, S Karlsson Leukemia 26 (11), 2416-2419, 2012 | 19 | 2012 |
Diamond-Blackfan anemia: pathogenesis, management and development of future therapies P Jaako, J Flygare, S Karlsson Hematology education: the education program for the annual congress of the …, 2013 | 9 | 2013 |
Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia P Jaako, A Ugale, M Wahlestedt, T Velasco-Hernandez, J Cammenga, ... Leukemia 31 (1), 213-221, 2017 | 7 | 2017 |
Ducou le Pointe H, Fumagalli S, Beaupain B, Nitschké P, Bôle-Feysot C, de Villartay JP, Bellanné-Chantelot C, Donadieu J, Kannengiesser C, Warren AJ, Revy P. EFL1 mutations … S Tan, L Kermasson, A Hoslin, P Jaako, A Faille, A Acevedo-Arozena, ... Blood 134 (3), 277-290, 2019 | 6 | 2019 |
The chemical landscape of the human ribosome at 1.67 Å resolution A Faille, KC Dent, S Pellegrino, P Jaako, AJ Warren bioRxiv, 2023.02. 28.530191, 2023 | 3 | 2023 |
Glucocorticoids reduce expression of p53 target genes and reverse anemia in a mouse model of Diamond-Blackfan anemia S Sjögren, P Jaako, S Karlsson, J Flygare Blood, The Journal of the American Society of Hematology 122 (21), 3703-3703, 2013 | 3 | 2013 |
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition. P Jaako, J Flygare, K Olsson, A Schambach, C Baum, J Larsson, D Bryder, ... Blood 114 (22), 178, 2009 | 3 | 2009 |
Bone marrow failure in RPS19-deficient mice is partly caused by p53 activation and responds to L-Leucine treatment P Jaako, S Debnath, K Olsson, J Flygare, S Karlsson Blood 118 (21), 727, 2011 | 2 | 2011 |
Chronic RPS19 deficiency leads to bone marrow failure in a mouse model for Diamond-Blackfan anemia P Jaako, J Flygare, K Olsson, R Quere, J Larsson, D Bryder, S Karlsson Blood 116 (21), 193, 2010 | 2 | 2010 |
Defective ribosome assembly impairs leukemia stem cell function in a murine model of acute myeloid leukemia D Sjövall, S Ghosh, J Hansson, C Guibentif, P Jaako bioRxiv, 2023.01. 22.525120, 2023 | 1 | 2023 |