Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level K Ewert, NL Slack, A Ahmad, HM Evans, AJ Lin, CE Samuel, CR Safinya Current medicinal chemistry 11 (2), 133-149, 2004 | 285 | 2004 |
A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice KK Ewert, HM Evans, A Zidovska, NF Bouxsein, A Ahmad, CR Safinya Journal of the American Chemical Society 128 (12), 3998-4006, 2006 | 279 | 2006 |
Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA NF Bouxsein, CS McAllister, KK Ewert, CE Samuel, CR Safinya Biochemistry 46 (16), 4785-4792, 2007 | 252 | 2007 |
New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid–DNA complexes for gene delivery A Ahmad, HM Evans, K Ewert, CX George, CE Samuel, CR Safinya The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 228 | 2005 |
Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix C Leal, NF Bouxsein, KK Ewert, CR Safinya Journal of the American Chemical Society 132 (47), 16841-16847, 2010 | 202 | 2010 |
Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways K Ewert, A Ahmad, HM Evans, CR Safinya Expert opinion on biological therapy 5 (1), 33-53, 2005 | 190 | 2005 |
Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery K Ewert, A Ahmad, HM Evans, HW Schmidt, CR Safinya Journal of medicinal chemistry 45 (23), 5023-5029, 2002 | 176 | 2002 |
Cationic liposome–nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA KK Ewert, A Zidovska, A Ahmad, NF Bouxsein, HM Evans, CS McAllister, ... Nucleic Acid Transfection, 191-226, 2010 | 172 | 2010 |
Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid CL Chan, RN Majzoub, RS Shirazi, KK Ewert, YJ Chen, KS Liang, ... Biomaterials 33 (19), 4928-4935, 2012 | 166 | 2012 |
Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of interprotofilament interactions DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, JB Jones, HP Miller, ... Physical review letters 93 (19), 198104, 2004 | 137 | 2004 |
Cationic liposome–nucleic acid complexes for gene delivery and gene silencing CR Safinya, KK Ewert, RN Majzoub, C Leal New Journal of Chemistry 38 (11), 5164-5172, 2014 | 109 | 2014 |
Structural polymorphism of DNA-dendrimer complexes HM Evans, A Ahmad, K Ewert, T Pfohl, A Martin-Herranz, RF Bruinsma, ... Physical review letters 91 (7), 075501, 2003 | 101 | 2003 |
Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery RS Shirazi, KK Ewert, C Leal, RN Majzoub, NF Bouxsein, CR Safinya Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (9), 2156-2166, 2011 | 98 | 2011 |
Radial compression of microtubules and the mechanism of action of taxol and associated proteins DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, HP Miller, L Wilson, ... Biophysical journal 89 (5), 3410-3423, 2005 | 98 | 2005 |
Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, EL Jacovetty, ... Biomaterials 35 (18), 4996-5005, 2014 | 94 | 2014 |
Materials chemistry: liposomes derived from molecular vases CR Safinya, KK Ewert Nature 489 (7416), 372, 2012 | 94 | 2012 |
Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing RN Majzoub, KK Ewert, CR Safinya Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016 | 90 | 2016 |
Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications CR Safinya, K Ewert, A Ahmad, HM Evans, U Raviv, DJ Needleman, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2006 | 89 | 2006 |
Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes A Martin-Herranz, A Ahmad, HM Evans, K Ewert, U Schulze, CR Safinya Biophysical journal 86 (2), 1160-1168, 2004 | 87 | 2004 |
Lipoplex structures and their distinct cellular pathways K Ewert, HM Evans, A Ahmad, NL Slack, AJ Lin, A Martin‐Herranz, ... Advances in genetics 53, 119-155, 2005 | 77 | 2005 |