Non-viral vectors for gene-based therapy H Yin, RL Kanasty, AA Eltoukhy, AJ Vegas, JR Dorkin, DG Anderson Nature reviews genetics 15 (8), 541-555, 2014 | 3311 | 2014 |
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype H Yin, W Xue, S Chen, RL Bogorad, E Benedetti, M Grompe, ... Nature biotechnology 32 (6), 551-553, 2014 | 1208 | 2014 |
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 954 | 2016 |
CRISPR-mediated direct mutation of cancer genes in the mouse liver W Xue, S Chen, H Yin, T Tammela, T Papagiannakopoulos, NS Joshi, ... Nature 514 (7522), 380-384, 2014 | 877 | 2014 |
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ... Nature nanotechnology 9 (8), 648-655, 2014 | 672 | 2014 |
Delivery technologies for genome editing H Yin, KJ Kauffman, DG Anderson Nature reviews Drug discovery 16 (6), 387-399, 2017 | 578 | 2017 |
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ... Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014 | 507 | 2014 |
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 489 | 2017 |
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ... Human gene therapy 26 (7), 432-442, 2015 | 398 | 2015 |
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity H Yin, CQ Song, S Suresh, SY Kwan, Q Wu, S Walsh, J Ding, RL Bogorad, ... Nature chemical biology 14 (3), 311-316, 2018 | 237 | 2018 |
Genome editing with mRNA encoding ZFN, TALEN, and Cas9 HX Zhang, Y Zhang, H Yin Molecular Therapy 27 (4), 735-746, 2019 | 233 | 2019 |
Role of hepatic resident and infiltrating macrophages in liver repair after acute injury Q You, M Holt, H Yin, G Li, CJ Hu, C Ju Biochemical Pharmacology 86 (6), 836-843, 2013 | 199 | 2013 |
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion H Mou, JL Smith, L Peng, H Yin, J Moore, XO Zhang, CQ Song, A Sheel, ... Genome biology 18, 1-8, 2017 | 193 | 2017 |
CRISPR–Cas: a tool for cancer research and therapeutics H Yin, W Xue, DG Anderson Nature reviews Clinical oncology 16 (5), 281-295, 2019 | 184 | 2019 |
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery CA Alabi, KT Love, G Sahay, H Yin, KM Luly, R Langer, DG Anderson Proceedings of the National Academy of Sciences 110 (32), 12881-12886, 2013 | 182 | 2013 |
Adenine base editing in an adult mouse model of tyrosinaemia CQ Song, T Jiang, M Richter, LH Rhym, LW Koblan, MP Zafra, ... Nature biomedical engineering 4 (1), 125-130, 2020 | 167 | 2020 |
Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas JM Fritz, MA Tennis, DJ Orlicky, H Yin, C Ju, EF Redente, KS Choo, ... Frontiers in immunology 5, 587, 2014 | 164 | 2014 |
Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a S Lu, X Tong, Y Han, K Zhang, Y Zhang, Q Chen, J Duan, X Lei, M Huang, ... Nature biomedical engineering 6 (3), 286-297, 2022 | 140 | 2022 |
Precision cancer mouse models through genome editing with CRISPR-Cas9 H Mou, Z Kennedy, DG Anderson, H Yin, W Xue Genome medicine 7, 1-11, 2015 | 127 | 2015 |
Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice CQ Song, Y Li, H Mou, J Moore, A Park, Y Pomyen, S Hough, Z Kennedy, ... Gastroenterology 152 (5), 1161-1173. e1, 2017 | 123 | 2017 |