| Spirocyclic scaffolds in medicinal chemistry K Hiesinger, D Dar’in, E Proschak, M Krasavin Journal of Medicinal Chemistry 64 (1), 150-183, 2020 | 351 | 2020 |
| Discovery of the first in vivo active inhibitors of the soluble epoxide hydrolase phosphatase domain JS Kramer, S Woltersdorf, T Duflot, K Hiesinger, FF Lillich, F Knöll, ... Journal of medicinal chemistry 62 (18), 8443-8460, 2019 | 36 | 2019 |
| Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity K Hiesinger, KM Wagner, BD Hammock, E Proschak, SH Hwang Prostaglandins & other lipid mediators 140, 31-39, 2019 | 33 | 2019 |
| Preparative Scale Applications of C− H Activation in Medicinal Chemistry R de Jesus, K Hiesinger, M van Gemmeren Angewandte Chemie International Edition 62 (45), e202306659, 2023 | 17 | 2023 |
| Design, synthesis, and structure–activity relationship studies of dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase K Hiesinger, JS Kramer, S Beyer, T Eckes, S Brunst, C Flauaus, ... Journal of Medicinal Chemistry 63 (20), 11498-11521, 2020 | 15 | 2020 |
| Pyrazolo [1, 5a] pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors S Hauck, K Hiesinger, SK Hosseini, J Achenbach, RM Biondi, E Proschak, ... Bioorganic & Medicinal Chemistry 24 (22), 5717-5729, 2016 | 14 | 2016 |
| Systematic assessment of fragment identification for multitarget drug design S Brunst, JS Kramer, W Kilu, J Heering, J Pollinger, K Hiesinger, ... ChemMedChem 16 (7), 1088-1092, 2021 | 10 | 2021 |
| Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase K Hiesinger, A Schott, JS Kramer, R Blöcher, F Witt, SK Wittmann, ... ACS Medicinal Chemistry Letters 11 (3), 298-302, 2019 | 10 | 2019 |
| Computer-aided fragment growing strategies to design dual inhibitors of soluble epoxide hydrolase and LTA4 hydrolase L Hefke, K Hiesinger, WF Zhu, JS Kramer, E Proschak ACS Medicinal Chemistry Letters 11 (6), 1244-1249, 2020 | 9 | 2020 |
| Computer-aided selective optimization of side activities of talinolol K Hiesinger, JS Kramer, J Achenbach, D Moser, J Weber, SK Wittmann, ... ACS Medicinal Chemistry Letters 10 (6), 899-903, 2019 | 8 | 2019 |
| Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells S Brunst, J Schönfeld, P Breunig, LD Burgers, M DeMeglio, JHM Ehrler, ... ACS Medicinal Chemistry Letters 13 (7), 1062-1067, 2022 | 2 | 2022 |
| Pd-catalysed direct β-C(sp3)–H fluorination of aliphatic carboxylic acids S Mal, F Jurk, K Hiesinger, M van Gemmeren Nature Synthesis, 1-7, 2024 | 1 | 2024 |
| Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator L Dötsch, C Davies, E Hennes, J Schönfeld, A Kumar, CDCL Guita, ... Journal of Medicinal Chemistry 67 (6), 4691-4706, 2024 | 1 | 2024 |
| The Direct β-C (sp3)–H Fluorination of Carboxylic Acids S Mal, F Jurk, K Hiesinger, M van Gemmeren | | 2024 |
| Anwendungen der C− H‐Aktivierung im präparativen Maßstab in der medizinischen Chemie R de Jesus, K Hiesinger, M van Gemmeren Angewandte Chemie 135 (45), e202306659, 2023 | | 2023 |
| Discovery of novel inhibitors of the phosphatase activity of the soluble epoxide hydrolase JS Kramer, S Woltersdorf, S Wittmann, K Hiesinger, F Klingler, J Heering, ... The FASEB Journal 32, 558.3-558.3, 2018 | | 2018 |
