A reference panel of 64,976 haplotypes for genotype imputation Nature genetics 48 (10), 1279-1283, 2016 | 2941 | 2016 |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 602 | 2016 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 599 | 2018 |
Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model HJ Westeneng, TPA Debray, AE Visser, RPA van Eijk, JPK Rooney, ... The Lancet Neurology 17 (5), 423-433, 2018 | 449 | 2018 |
Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS BN Smith, N Ticozzi, C Fallini, AS Gkazi, S Topp, KP Kenna, EL Scotter, ... Neuron 84 (2), 324-331, 2014 | 418 | 2014 |
Evidence for an oligogenic basis of amyotrophic lateral sclerosis M Van Blitterswijk, MA Van Es, EAM Hennekam, D Dooijes, ... Human molecular genetics 21 (17), 3776-3784, 2012 | 409 | 2012 |
Genetic correlations of polygenic disease traits: from theory to practice W Van Rheenen, WJ Peyrot, AJ Schork, SH Lee, NR Wray Nature Reviews Genetics 20 (10), 567-581, 2019 | 344 | 2019 |
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 305 | 2021 |
NEK1 variants confer susceptibility to amyotrophic lateral sclerosis KP Kenna, PTC Van Doormaal, AM Dekker, N Ticozzi, BJ Kenna, ... Nature genetics 48 (9), 1037-1042, 2016 | 295 | 2016 |
Population genetic differentiation of height and body mass index across Europe MR Robinson, G Hemani, C Medina-Gomez, M Mezzavilla, T Esko, ... Nature genetics 47 (11), 1357-1362, 2015 | 221 | 2015 |
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis MA Van Es, HJ Schelhaas, PWJ Van Vught, N Ticozzi, PM Andersen, ... Annals of neurology 70 (6), 964-973, 2011 | 214 | 2011 |
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors MK Bakker, RAA van der Spek, W van Rheenen, S Morel, R Bourcier, ... Nature genetics 52 (12), 1303-1313, 2020 | 203 | 2020 |
The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease CM Lill, A Rengmark, L Pihlstrøm, I Fogh, A Shatunov, PM Sleiman, ... Alzheimer's & Dementia 11 (12), 1407-1416, 2015 | 176 | 2015 |
A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories C Akimoto, AE Volk, M van Blitterswijk, M Van den Broeck, CS Leblond, ... Journal of medical genetics 51 (6), 419-424, 2014 | 146 | 2014 |
UNC13A is a modifier of survival in amyotrophic lateral sclerosis FP Diekstra, PWJ van Vught, W van Rheenen, M Koppers, RJ Pasterkamp, ... Neurobiology of aging 33 (3), 630. e3-630. e8, 2012 | 142 | 2012 |
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis European Journal of Human Genetics 26 (10), 1537-1546, 2018 | 138 | 2018 |
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia RL McLaughlin, D Schijven, W Van Rheenen, KR Van Eijk, M O’brien, ... Nature communications 8 (1), 14774, 2017 | 138 | 2017 |
Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases W Van Rheenen, M Van Blitterswijk, MHB Huisman, L Vlam, ... Neurology 79 (9), 878-882, 2012 | 134 | 2012 |
Genomic signals of migration and continuity in Britain before the Anglo-Saxons R Martiniano, A Caffell, M Holst, K Hunter-Mann, J Montgomery, ... Nature communications 7 (1), 10326, 2016 | 127 | 2016 |
Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases N de Klein, EA Tsai, M Vochteloo, D Baird, Y Huang, CY Chen, ... Nature genetics 55 (3), 377-388, 2023 | 123 | 2023 |