Next-generation metal anticancer complexes: multitargeting via redox modulation I Romero-Canelon, PJ Sadler Inorganic chemistry 52 (21), 12276-12291, 2013 | 446 | 2013 |
The potent oxidant anticancer activity of organoiridium catalysts Z Liu, I Romero‐Canelón, B Qamar, JM Hearn, A Habtemariam, ... Angewandte Chemie 126 (15), 4022-4027, 2014 | 337 | 2014 |
Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design JJ Soldevila-Barreda, I Romero-Canelón, A Habtemariam, PJ Sadler Nature communications 6 (1), 1-9, 2015 | 252 | 2015 |
The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo-and imino-pyridine anticancer complexes: control of cell selectivity, cross-resistance, p53 … I Romero-Canelón, L Salassa, PJ Sadler Journal of medicinal chemistry 56 (3), 1291-1300, 2013 | 248 | 2013 |
Asymmetric transfer hydrogenation by synthetic catalysts in cancer cells JPC Coverdale, I Romero-Canelón, C Sanchez-Cano, GJ Clarkson, ... Nature chemistry 10 (3), 347-354, 2018 | 194 | 2018 |
Designing ruthenium anticancer drugs: What have we learnt from the key drug candidates? JPC Coverdale, T Laroiya-McCarron, I Romero-Canelón Inorganics 7 (3), 31, 2019 | 162 | 2019 |
Organometallic iridium (III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis JM Hearn, I Romero-Canelón, B Qamar, Z Liu, I Hands-Portman, ... ACS chemical biology 8 (6), 1335-1343, 2013 | 157 | 2013 |
Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C∧N-Chelated and Pyridine Ligands Z Liu, I Romero-Canelón, A Habtemariam, GJ Clarkson, PJ Sadler Organometallics 33 (19), 5324-5333, 2014 | 131 | 2014 |
Nanoparticles of chitosan conjugated to organo-ruthenium complexes Y Wang, A Pitto-Barry, A Habtemariam, I Romero-Canelon, PJ Sadler, ... Inorganic Chemistry Frontiers 3 (8), 1058-1064, 2016 | 124 | 2016 |
Supramolecular photoactivatable anticancer hydrogels V Venkatesh, NK Mishra, I Romero-Canelón, RR Vernooij, H Shi, ... Journal of the American Chemical Society 139 (16), 5656-5659, 2017 | 122 | 2017 |
Contrasting anticancer activity of half-sandwich iridium (III) complexes bearing functionally diverse 2-phenylpyridine ligands AJ Millett, A Habtemariam, I Romero-Canelón, GJ Clarkson, PJ Sadler Organometallics 34 (11), 2683-2694, 2015 | 121 | 2015 |
Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis L Song, M Jenner, J Masschelein, C Jones, MJ Bull, SR Harris, ... Journal of the American Chemical Society 139 (23), 7974-7981, 2017 | 99 | 2017 |
Cyclic peptide–polymer nanotubes as efficient and highly potent drug delivery systems for organometallic anticancer complexes SC Larnaudie, JC Brendel, I Romero-Canelón, C Sanchez-Cano, ... Biomacromolecules 19 (1), 239-247, 2018 | 95 | 2018 |
Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cells JO Suberu, I Romero-Canelón, N Sullivan, AA Lapkin, GC Barker ChemMedChem 9 (12), 2791, 2014 | 93 | 2014 |
Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells JM Hearn, I Romero-Canelón, AF Munro, Y Fu, AM Pizarro, MJ Garnett, ... Proceedings of the National Academy of Sciences 112 (29), E3800-E3805, 2015 | 88 | 2015 |
In‐Cell Activation of Organo‐Osmium (II) Anticancer Complexes RJ Needham, C Sanchez‐Cano, X Zhang, I Romero‐Canelón, ... Angewandte Chemie International Edition 56 (4), 1017-1020, 2017 | 85 | 2017 |
Synchrotron X‐ray fluorescence nanoprobe reveals target sites for organo‐osmium complex in human ovarian cancer cells C Sanchez‐Cano, I Romero‐Canelón, Y Yang, IJ Hands‐Portman, ... Chemistry (Weinheim an der Bergstrasse, Germany) 23 (11), 2512, 2017 | 83 | 2017 |
Enhancement of selectivity of an organometallic anticancer agent by redox modulation I Romero-Canelón, M Mos, PJ Sadler Journal of medicinal chemistry 58 (19), 7874-7880, 2015 | 81 | 2015 |
Half-sandwich arene ruthenium (II) and osmium (II) thiosemicarbazone complexes: solution behavior and antiproliferative activity A Gatti, A Habtemariam, I Romero-Canelón, JI Song, B Heer, GJ Clarkson, ... Organometallics 37 (6), 891-899, 2018 | 76 | 2018 |
A novel dual-functioning ruthenium (II)–arene complex of an anti-microbial ciprofloxacin derivative—Anti-proliferative and anti-microbial activity Z Ude, I Romero-Canelón, B Twamley, DF Hughes, PJ Sadler, ... Journal of inorganic biochemistry 160, 210-217, 2016 | 73 | 2016 |