| Effect of targeted polymyxin B hemoperfusion on 28-day mortality in patients with septic shock and elevated endotoxin level: the EUPHRATES randomized clinical trial RP Dellinger, SM Bagshaw, M Antonelli, DM Foster, DJ Klein, JC Marshall, ... Jama 320 (14), 1455-1463, 2018 | 383 | 2018 |
| Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury R Wald, NKJ Adhikari, OM Smith, MA Weir, K Pope, A Cohen, K Thorpe, ... Kidney international 88 (4), 897-904, 2015 | 253 | 2015 |
| Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial DJ Klein, D Foster, PM Walker, SM Bagshaw, H Mekonnen, M Antonelli Intensive care medicine 44, 2205-2212, 2018 | 205 | 2018 |
| The EUPHRATES trial (Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized controlled trial of Adults Treated for Endotoxemia and Septic shock): study protocol for a … DJ Klein, D Foster, CA Schorr, K Kazempour, PM Walker, RP Dellinger Trials 15, 1-15, 2014 | 145 | 2014 |
| The value of serum biomarkers in prediction models of outcome after mild traumatic brain injury J Topolovec-Vranic, MA Pollmann-Mudryj, D Ouchterlony, D Klein, ... Journal of Trauma and Acute Care Surgery 71 (5), S478-S486, 2011 | 144 | 2011 |
| Polymyxin B hemoperfusion: a mechanistic perspective C Ronco, DJ Klein Critical Care 18, 1-8, 2014 | 128 | 2014 |
| Bench-to-bedside review: clinical experience with the endotoxin activity assay AD Romaschin, DJ Klein, JC Marshall Critical Care 16, 1-9, 2012 | 88 | 2012 |
| Outcomes of sustained low efficiency dialysis versus continuous renal replacement therapy in critically ill adults with acute kidney injury: a cohort study A Kitchlu, N Adhikari, KEA Burns, JO Friedrich, AX Garg, D Klein, ... BMC nephrology 16, 1-8, 2015 | 74 | 2015 |
| Optimal Mode of clearance in critically ill patients with Acute Kidney Injury (OMAKI)-a pilot randomized controlled trial of hemofiltration versus hemodialysis: a Canadian … R Wald, JO Friedrich, SM Bagshaw, KEA Burns, AX Garg, ... Critical care 16, 1-9, 2012 | 71 | 2012 |
| Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational study DJ Klein, F Briet, R Nisenbaum, AD Romaschin, CD Mazer Critical care 15, 1-6, 2011 | 61 | 2011 |
| Daily variation in endotoxin levels is associated with increased organ failure in critically ill patients DJ Klein, A Derzko, D Foster, AJE Seely, F Brunet, AD Romaschin, ... Shock 28 (5), 524-529, 2007 | 60 | 2007 |
| Novel insights into the direct removal of endotoxin by polymyxin B hemoperfusion AD Romaschin, CV Obiezu-Forster, H Shoji, DJ Klein Blood Purification 44 (3), 193-197, 2017 | 54 | 2017 |
| Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study K Neill, J Barton, E Karen, A Burns, JO Friedrich, D Klein, S Litwin, ... Canadian Journal of Anesthesia 59 (10), 934, 2012 | 53 | 2012 |
| Endotoxemia following multiple trauma: risk factors and prognostic implications E Charbonney, JY Tsang, Y Li, D Klein, P Duque, A Romaschin, ... Critical care medicine 44 (2), 335-341, 2016 | 46 | 2016 |
| Combining intermediate levels of the Endotoxin Activity Assay (EAA) with other biomarkers in the assessment of patients with sepsis: results of an observational study A Yaguchi, J Yuzawa, DJ Klein, M Takeda, T Harada Critical care 16, 1-8, 2012 | 45 | 2012 |
| A multicenter, randomized, double-blind study of ulimorelin and metoclopramide in the treatment of critically ill patients with enteral feeding intolerance: PROMOTE trial DK Heyland, ARH van Zanten, T Grau-Carmona, D Evans, A Beishuizen, ... Intensive care medicine 45, 647-656, 2019 | 34 | 2019 |
| Intensive care of the patient following open abdominal aortic surgery G Papia, D Klein, TF Lindsay Current Opinion in Critical Care 12 (4), 340-345, 2006 | 33 | 2006 |
| The wind changed direction and the big river still flows: from EUPHRATES to TIGRIS T Iba, DJ Klein Journal of Intensive Care 7, 1-2, 2019 | 19 | 2019 |
| Extrauterine twin-twin transfusion affects renal function and perioperative management of conjoined twins DJ Klein, RM Filler, KS Azarow, DF Geary Journal of pediatric surgery 33 (2), 354-356, 1998 | 19 | 1998 |
| Inter-hospital transfers and outcomes of critically ill patients with severe acute kidney injury: a multicenter cohort study P Kudlow, KEA Burns, NKJ Adhikari, B Bell, DJ Klein, B Xie, JO Friedrich, ... Critical Care 18, 1-7, 2014 | 18 | 2014 |
