Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone TT Price, ML Burness, A Sivan, MJ Warner, R Cheng, CH Lee, L Olivere, ... Science translational medicine 8 (340), 340ra73-340ra73, 2016 | 239 | 2016 |
Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer Q Cheng, JT Chang, J Geradts, LM Neckers, T Haystead, NL Spector, ... Breast cancer research 14, 1-15, 2012 | 201 | 2012 |
Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics L Kager, M Cheok, W Yang, G Zaza, Q Cheng, JC Panetta, CH Pui, ... The Journal of clinical investigation 115 (1), 110-117, 2005 | 193 | 2005 |
An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models W Xia, EF Petricoin, S Zhao, L Liu, T Osada, Q Cheng, JD Wulfkuhle, ... Breast Cancer Research 15, 1-15, 2013 | 160 | 2013 |
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells B Diouf, Q Cheng, NF Krynetskaia, W Yang, M Cheok, D Pei, Y Fan, ... Nature medicine 17 (10), 1298-1303, 2011 | 142 | 2011 |
A substrate specific functional polymorphism of human γ-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic … Q Cheng, B Wu, L Kager, JC Panetta, J Zheng, CH Pui, MV Relling, ... Pharmacogenetics and Genomics 14 (8), 557-567, 2004 | 111 | 2004 |
Pre-existing castration-resistant prostate cancer–like cells in primary prostate cancer promote resistance to hormonal therapy Q Cheng, W Butler, Y Zhou, H Zhang, L Tang, K Perkinson, X Chen, ... European urology 81 (5), 446-455, 2022 | 99 | 2022 |
Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer Y Li, Y He, W Butler, L Xu, Y Chang, K Lei, H Zhang, Y Zhou, AC Gao, ... Science translational medicine 11 (521), eaax0428, 2019 | 97 | 2019 |
Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis C Palena, M Roselli, MT Litzinger, P Ferroni, L Costarelli, A Spila, ... Journal of the National Cancer Institute 106 (5), dju054, 2014 | 85 | 2014 |
Karyotypic abnormalities create discordance of germline genotype and cancer cell phenotypes Q Cheng, WJ Yang, SC Raimondi, CH Pui, MV Relling, WE Evans Nature genetics 37 (8), 878-882, 2005 | 84 | 2005 |
Identification and characterization of genes involved in the carcinogenesis of human squamous cell cervical carcinoma Q Cheng, WM Lau, SK Tay, SH Chew, TH Ho, KM Hui International journal of cancer 98 (3), 419-426, 2002 | 74 | 2002 |
Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix Q Cheng, WM Lau, SH Chew, TH Ho, SK Tay, KM Hui British journal of cancer 86 (2), 274-281, 2002 | 67 | 2002 |
A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype Q Cheng, JT Chang, WR Gwin, J Zhu, S Ambs, J Geradts, HK Lyerly Breast Cancer Research 16, 1-13, 2014 | 62 | 2014 |
Epigenetic regulation of human γ-glutamyl hydrolase activity in acute lymphoblastic leukemia cells Q Cheng, C Cheng, KR Crews, RC Ribeiro, CH Pui, MV Relling, ... The American Journal of Human Genetics 79 (2), 264-274, 2006 | 46 | 2006 |
ROS1-fusion protein induces PD-L1 expression via MEK-ERK activation in non-small cell lung cancer Z Liu, K Zhao, S Wei, C Liu, J Zhou, Q Gou, X Wu, Z Yang, Y Yang, ... Oncoimmunology 9 (1), 1758003, 2020 | 23 | 2020 |
A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors Q Cheng, X Li, CR Acharya, T Hyslop, JA Sosa Oncotarget 8 (10), 16690, 2017 | 21 | 2017 |
An age-independent gene signature for monitoring acute rejection in kidney transplantation BI Shaw, DK Cheng, CR Acharya, RB Ettenger, HK Lyerly, Q Cheng, ... Theranostics 10 (15), 6977, 2020 | 12 | 2020 |
Cancer pharmacogenomics may require both qualitative and quantitative approaches Q Cheng, WE Evans Cell Cycle 4 (11), 1506-1509, 2005 | 9 | 2005 |
Oncofetal protein glypican‐3 is a biomarker and critical regulator of function for neuroendocrine cells in prostate cancer W Butler, L Xu, Y Zhou, Q Cheng, JS Hauck, Y He, R Marek, Z Hartman, ... The Journal of Pathology 260 (1), 43-55, 2023 | 7 | 2023 |
Multicellular ecotypes shape progression of lung adenocarcinoma from ground-glass opacity toward advanced stages Y Deng, L Xia, J Zhang, S Deng, M Wang, S Wei, K Li, H Lai, Y Yang, ... Cell Reports Medicine, 2024 | 2 | 2024 |