| In vivo knockout of the Vegfa gene by lentiviral delivery of CRISPR/Cas9 in mouse retinal pigment epithelium cells A Holmgaard, AL Askou, JNE Benckendorff, EA Thomsen, Y Cai, T Bek, ... Molecular Therapy-Nucleic Acids 9, 89-99, 2017 | 76 | 2017 |
| pegIT-a web-based design tool for prime editing MV Anderson, J Haldrup, EA Thomsen, JH Wolff, JG Mikkelsen Nucleic Acids Research 49 (W1), W505-W509, 2021 | 42 | 2021 |
| MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma H Due, AA Schönherz, L Ryø, MN Primo, DS Jespersen, EA Thomsen, ... Blood advances 3 (7), 1185-1196, 2019 | 26 | 2019 |
| Production and validation of lentiviral vectors for CRISPR/Cas9 delivery LB Ryø, EA Thomsen, JG Mikkelsen CRISPR Gene Editing: Methods and Protocols, 93-109, 2019 | 24 | 2019 |
| Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification J Haldrup, S Andersen, ARLV Labial, JH Wolff, FP Frandsen, TW Skov, ... Nucleic Acids Research 51 (18), 10059-10074, 2023 | 21 | 2023 |
| A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer MB Ipsen, EMG Sørensen, EA Thomsen, S Weiss, J Haldrup, A Dalby, ... Oncogene 41 (37), 4271-4281, 2022 | 20 | 2022 |
| piggyPrime: High-efficacy prime editing in human cells using piggyBac-based DNA transposition JH Wolff, J Haldrup, EA Thomsen, S Andersen, JG Mikkelsen Frontiers in Genome Editing 3, 786893, 2021 | 19 | 2021 |
| Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma EA Thomsen, AB Rovsing, MV Anderson, H Due, J Huang, Y Luo, ... Molecular Oncology 14 (9), 1978-1997, 2020 | 19 | 2020 |
| CRISPR-based lentiviral knockout libraries for functional genomic screening and identification of phenotype-related genes EA Thomsen, JG Mikkelsen CRISPR Gene Editing: Methods and Protocols, 343-357, 2019 | 16 | 2019 |
| CRISPR-screen identifies ZIP9 and dysregulated Zn2+ homeostasis as a cause of cancer-associated changes in glycosylation TB Rømer, F Khoder-Agha, MKM Aasted, N de Haan, S Horn, A Dylander, ... Glycobiology 33 (9), 700-714, 2023 | 10 | 2023 |
| Resistance to vincristine in DLBCL by disruption of p53‐induced cell cycle arrest and apoptosis mediated by KIF18B and USP28 AB Rovsing, EA Thomsen, I Nielsen, TW Skov, Y Luo, K Dybkær, ... British Journal of Haematology 202 (4), 825-839, 2023 | 10 | 2023 |
| MicroRNA-106b regulates expression of the tumour suppressors p21 and TXNIP and promotes tumour cell proliferation in mycosis fungoides LM Lindahl, M Gluud, T Emmanuel, EA Thomsen, HU Tengpeng, ... Acta Dermato-Venereologica 100 (16), 5824, 2020 | 9 | 2020 |
| TMEFF1 is a neuron-specific restriction factor for herpes simplex virus Y Dai, M Idorn, MC Serrero, X Pan, EA Thomsen, R Narita, M Maimaitili, ... Nature 632 (8024), 383-389, 2024 | 6 | 2024 |
| An extended PD-L2 cytoplasmic domain results from alternative splicing in NSCLC cells LL Dietz, NT Furman, TV Larsen, TF Daugaard, EA Thomsen, JL Keller, ... Journal of Immunotherapy 45 (9), 379-388, 2022 | 6 | 2022 |
| Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression EA Thomsen, S Andersen, MHS Marqvorsen, KA Skipper, SR Paludan, ... Frontiers in cellular and infection microbiology 11, 784762, 2022 | 6 | 2022 |
| CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch EA Thomsen, KA Skipper, S Andersen, D Haslund, TW Skov, ... Molecular Therapy-Nucleic Acids 29, 563-576, 2022 | 4 | 2022 |
| Cell-targeted gene modification by delivery of CRISPR-Cas9 ribonucleoprotein complexes in pseudotyped lentivirus-derived nanoparticles IH Nielsen, AB Rovsing, JH Janns, EA Thomsen, A Ruzo, A Bøggild, ... Molecular Therapy Nucleic Acids 35 (4), 2024 | 3 | 2024 |
| Lentivirus-derived nanoparticles comprising crispr/cas9 ribonucleoprotein complexes MV Anderson, JG Mikkelsen, KA Skipper, EA Thomsen, S Andersen, ... US Patent App. 18/562,938, 2024 | | 2024 |
| Genome-Scale CRISPRa and CRISPRi screening for lncRNA drivers of prostate cancer progression S Weiss, A Lord, B Schmierer, AB Rovsing, EA Thomsen, JG Mikkelsen, ... Cancer Research 83 (7_Supplement), 3778-3778, 2023 | | 2023 |
| Resistance to vincristine in cancerous B-cells by disruption of p53-dependent mitotic surveillance AB Rovsing, EA Thomsen, I Nielsen, TW Skov, Y Luo, K Dybkær, ... bioRxiv, 2023.01. 19.524713, 2023 | | 2023 |
