Identification of genetic factors that modify clinical onset of Huntington’s disease JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ... Cell 162 (3), 516-526, 2015 | 457 | 2015 |
The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal M Rosas, LC Davies, PJ Giles, CT Liao, B Kharfan, TC Stone, ... Science 344 (6184), 645-648, 2014 | 400 | 2014 |
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 335 | 2019 |
Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscanTM) platform J Webber, TC Stone, E Katilius, BC Smith, B Gordon, MD Mason, Z Tabi, ... Molecular & cellular proteomics 13 (4), 1050-1064, 2014 | 179 | 2014 |
Convergent genetic and expression data implicate immunity in Alzheimer's disease International Genomics of Alzheimer's Disease Consortium (IGAP), ... Alzheimer's & Dementia 11 (6), 658-671, 2015 | 161 | 2015 |
Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple sclerosis JL Welton, S Loveless, T Stone, C von Ruhland, NP Robertson, A Clayton Journal of extracellular vesicles 6 (1), 1369805, 2017 | 129 | 2017 |
Time‐series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis B Poulet, V Ulici, TC Stone, M Pead, V Gburcik, E Constantinou, ... Arthritis & Rheumatism 64 (10), 3256-3266, 2012 | 63 | 2012 |
RNA-Seq of Huntington’s disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation JRC Miller, KK Lo, R Andre, DJ Hensman Moss, U Träger, TC Stone, ... Human molecular genetics 25 (14), 2893-2904, 2016 | 62 | 2016 |
Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease DJ Hensman Moss, MD Flower, KK Lo, JRC Miller, GJB van Ommen, ... Scientific reports 7 (1), 44849, 2017 | 57 | 2017 |
miR-21 promotes fibrogenesis in peritoneal dialysis M Lopez-Anton, M Lambie, M Lopez-Cabrera, CP Schmitt, V Ruiz-Carpio, ... The American journal of pathology 187 (7), 1537-1550, 2017 | 42 | 2017 |
Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s disease N Ellis, A Tee, B McAllister, T Massey, D McLauchlan, T Stone, K Correia, ... Biological Psychiatry 87 (9), 857-865, 2020 | 36 | 2020 |
SMAD transcription factors are altered in cell models of HD and regulate HTT expression KR Bowles, T Stone, P Holmans, ND Allen, SB Dunnett, L Jones Cellular Signalling 31, 1-14, 2017 | 24 | 2017 |
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation YT Wong, MA Tayeb, TC Stone, LB Lovat, AE Teschendorff, R Iwasiow, ... Epigenetics 17 (3), 327-334, 2022 | 18 | 2022 |
Novel epigenetic network biomarkers for early detection of esophageal cancer AK Maity, TC Stone, V Ward, AP Webster, Z Yang, A Hogan, H McBain, ... Clinical Epigenetics 14 (1), 23, 2022 | 14 | 2022 |
Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence Z Bayram-Weston, TC Stone, P Giles, L Elliston, N Janghra, GV Higgs, ... BMC genomics 16, 1-14, 2015 | 11 | 2015 |
Silencing of essential genes within a highly coordinated operon in Escherichia coli S Goh, A Hohmeier, TC Stone, V Offord, F Sarabia, C Garcia-Ruiz, L Good Applied and Environmental Microbiology 81 (16), 5650-5659, 2015 | 10 | 2015 |
Exploring the Value of BRD9 as a Biomarker, Therapeutic Target and Co-Target in Prostate Cancer N Barma, TC Stone, LM Carmona Echeverria, S Heavey Biomolecules 11 (12), 1794, 2021 | 6 | 2021 |
Huntington’s disease onset is determined by length of uninterrupted CAG, not encoded polyglutamine, and is modified by DNA maintenance mechanisms Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, JM Lee, ... bioRxiv, 529768, 2019 | 6 | 2019 |
Gene array profiling of articular chondrocytes in mice with different susceptibility to natural disease reveals specific gene signatures linked to healthy ageing and spontaneous OA B Poulet, U Veronica, TC Stone, M Pead, V Gburcik, F Beier, JA Timmons, ... Osteoarthritis and Cartilage 20, S59-S60, 2012 | 3 | 2012 |
Using genomic data to find disease-modifying loci in Huntington’s disease (HD) P Holmans, T Stone Huntington’s Disease, 443-461, 2018 | 2 | 2018 |