The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer LH Matherly, MR Wilson, Z Hou Drug Metabolism and Disposition 42 (4), 632-649, 2014 | 107 | 2014 |
ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion MR Wilson, JJ Reske, J Holladay, GE Wilber, M Rhodes, J Koeman, ... Nature communications 10 (1), 3554, 2019 | 106 | 2019 |
ATAC-seq normalization method can significantly affect differential accessibility analysis and interpretation JJ Reske, MR Wilson, RL Chandler Epigenetics & chromatin 13 (1), 1-17, 2020 | 63 | 2020 |
6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human … L Wang, A Wallace, S Raghavan, SM Deis, MR Wilson, S Yang, L Polin, ... Journal of medicinal chemistry 58 (17), 6938-6959, 2015 | 55 | 2015 |
ARID1A mutations promote P300-dependent endometrial invasion through super-enhancer hyperacetylation MR Wilson, JJ Reske, J Holladay, S Neupane, J Ngo, N Cuthrell, ... Cell reports 33 (6), 2020 | 51 | 2020 |
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and … LK Golani, A Wallace-Povirk, SM Deis, J Wong, J Ke, X Gu, S Raghavan, ... Journal of medicinal chemistry 59 (17), 7856-7876, 2016 | 44 | 2016 |
Targeting nonsquamous nonsmall cell lung cancer via the proton-coupled folate transporter with 6-substituted pyrrolo [2, 3-d] pyrimidine thienoyl antifolates MR Wilson, Z Hou, S Yang, L Polin, J Kushner, K White, J Huang, ... Molecular pharmacology 89 (4), 425-434, 2016 | 43 | 2016 |
Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α … LK Golani, C George, S Zhao, S Raghavan, S Orr, A Wallace, MR Wilson, ... Journal of medicinal chemistry 57 (19), 8152-8166, 2014 | 38 | 2014 |
Fluorine-Substituted Pyrrolo[2,3-d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and … M Ravindra, MR Wilson, N Tong, C O’Connor, M Karim, L Polin, ... Journal of medicinal chemistry 61 (9), 4228-4248, 2018 | 32 | 2018 |
Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis JJ Reske, MR Wilson, J Holladay, RA Siwicki, H Skalski, S Harkins, ... PLoS Genetics 17 (12), e1009986, 2021 | 30 | 2021 |
A mouse model of endometriosis mimicking the natural spread of invasive endometrium MR Wilson, J Holladay, RL Chandler Human Reproduction 35 (1), 58-69, 2020 | 22 | 2020 |
Structural determinants of human proton-coupled folate transporter oligomerization: role of GXXXG motifs and identification of oligomeric interfaces at transmembrane domains 3 … MR Wilson, S Kugel, J Huang, LJ Wilson, PA Wloszczynski, J Ye, ... Biochemical Journal 469 (1), 33-44, 2015 | 18 | 2015 |
Substituted cysteine accessibility reveals a novel transmembrane 2–3 reentrant loop and functional role for transmembrane domain 2 in the human proton-coupled folate transporter MR Wilson, Z Hou, LH Matherly Journal of Biological Chemistry 289 (36), 25287-25295, 2014 | 18 | 2014 |
SWI/SNF Antagonism of PRC2 Mediates Estrogen-Induced Progesterone Receptor Expression MR Wilson, JJ Reske, J Koeman, M Adams, NR Joshi, AT Fazleabas, ... Cells 11 (6), 1000, 2022 | 14 | 2022 |
Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and … M Ravindra, A Wallace-Povirk, MA Karim, MR Wilson, C O’Connor, ... Journal of medicinal chemistry 61 (5), 2027-2040, 2018 | 14 | 2018 |
SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity JJ Reske, MR Wilson, J Holladay, M Wegener, M Adams, RL Chandler Human Molecular Genetics 29 (20), 3412-3430, 2020 | 12 | 2020 |
Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over … M Patki, T McFall, R Rosati, Y Huang, A Malysa, L Polin, A Fielder, ... Scientific Reports 8 (1), 16006, 2018 | 9 | 2018 |
AP-1 subunit JUNB promotes invasive phenotypes in endometriosis MR Wilson, JJ Reske, RL Chandler Reproductive Sciences 29 (11), 3266-3277, 2022 | 8 | 2022 |
ARID1A-dependent maintenance of H3. 3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers JJ Reske, MR Wilson, B Armistead, S Harkins, C Perez, J Hrit, M Adams, ... BMC biology 20 (1), 209, 2022 | 7 | 2022 |
Functional and mechanistic roles of the human proton-coupled folate transporter transmembrane domain 6–7 linker MR Wilson, Z Hou, LJ Wilson, J Ye, LH Matherly Biochemical Journal 473 (20), 3545-3562, 2016 | 7 | 2016 |