Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells AJ Rice, E Cortes, D Lachowski, BCH Cheung, SA Karim, JP Morton, ... Oncogenesis 6 (7), e352-e352, 2017 | 506 | 2017 |
Chemoresistance and the self-maintaining tumor microenvironment G Yeldag, A Rice, A del Río Hernández Cancers 10 (12), 471, 2018 | 184 | 2018 |
FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis D Lachowski, E Cortes, B Robinson, A Rice, K Rombouts, ... The FASEB Journal 32 (2), 1099-1107, 2018 | 176 | 2018 |
Protein disorder–order interplay to guide the growth of hierarchical mineralized structures S Elsharkawy, M Al-Jawad, MF Pantano, E Tejeda-Montes, K Mehta, ... Nature communications 9 (1), 2145, 2018 | 160 | 2018 |
Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis D Lachowski, E Cortes, A Rice, D Pinato, K Rombouts, ... Scientific reports 9 (1), 7299, 2019 | 129 | 2019 |
Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway A Chronopoulos, SD Thorpe, E Cortes, D Lachowski, AJ Rice, ... Nature materials 19 (6), 669-678, 2020 | 88 | 2020 |
Mechanotransduction in talin through the interaction of the R8 domain with DLC1 AWM Haining, R Rahikainen, E Cortes, D Lachowski, A Rice, ... PLoS biology 16 (7), e2005599, 2018 | 70 | 2018 |
Liquid biopsies for management of pancreatic cancer M Samandari, MG Julia, A Rice, A Chronopoulos, AE del Rio Hernandez Translational Research 201, 98-127, 2018 | 67 | 2018 |
Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells BK Robinson, E Cortes, AJ Rice, M Sarper, A del Río Hernández Biology open 5 (6), 875-882, 2016 | 57 | 2016 |
Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device–the SERCA-LVAD … AR Lyon, D Babalis, AC Morley-Smith, M Hedger, A Suarez Barrientos, ... Gene therapy 27 (12), 579-590, 2020 | 54 | 2020 |
Retinoic acid receptor‐β is downregulated in hepatocellular carcinoma and cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells E Cortes, D Lachowski, A Rice, A Chronopoulos, B Robinson, S Thorpe, ... Hepatology 69 (2), 785-802, 2019 | 54 | 2019 |
Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor E Cortes, D Lachowski, A Rice, SD Thorpe, B Robinson, G Yeldag, ... Oncogene 38 (16), 2910-2922, 2019 | 48 | 2019 |
Cross-linking of a biopolymer-peptide co-assembling system KE Inostroza-Brito, EC Collin, A Majkowska, S Elsharkawy, A Rice, ... Acta Biomaterialia 58, 80-89, 2017 | 25 | 2017 |
GPER activation inhibits cancer cell mechanotransduction and basement membrane invasion via RhoA A Rice, E Cortes, D Lachowski, P Oertle, C Matellan, SD Thorpe, R Ghose, ... Cancers 12 (2), 289, 2020 | 19 | 2020 |
The mutational landscape of pancreatic and liver cancers, as represented by circulating tumor DNA A Rice, A del Rio Hernandez Frontiers in oncology 9, 952, 2019 | 14 | 2019 |
Eukaryotic initiation factor 6 regulates mechanical responses in endothelial cells AN Keen, LA Payne, V Mehta, A Rice, LJ Simpson, KL Pang, ... Journal of Cell Biology 221 (2), e202005213, 2022 | 13 | 2022 |
G protein-coupled estrogen receptor regulates actin cytoskeleton dynamics to impair cell polarization D Lachowski, E Cortes, C Matellan, A Rice, DA Lee, SD Thorpe, ... Frontiers in cell and developmental biology 8, 592628, 2020 | 12 | 2020 |
Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression L Julian, G Naylor, GR Wickman, N Rath, G Castino, D Stevenson, ... Elife 10, e61983, 2021 | 11 | 2021 |
RAR-beta is downregulated in HCC & cirrhosis and its expression inhibits myosin-driven activation and durotaxis in hepatic stellate cells E Cortes, D Lachowski, A Rice, A Chronopoulos, B Robinson, S Thorpe, ... Hepatology 10, 2018 | 8 | 2018 |
Peptide–protein coassemblies into hierarchical and bioactive tubular membranes A Majkowska, KE Inostroza-Brito, M Gonzalez, C Redondo-Gómez, ... Biomacromolecules 24 (10), 4419-4429, 2023 | 4 | 2023 |