" Circlize" implements and enhances circular visualization in R Z Gu, L Gu, R Eils, M Schlesner, B Brors | 3085 | 2014 |
DNA methylation on N6-adenine in C. elegans EL Greer, MA Blanco, L Gu, E Sendinc, J Liu, D Aristizábal-Corrales, ... Cell 161 (4), 868-878, 2015 | 728 | 2015 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 644 | 2014 |
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ... Cell stem cell 15 (4), 507-522, 2014 | 573 | 2014 |
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer J Weischenfeldt, R Simon, L Feuerbach, K Schlangen, D Weichenhan, ... Cancer cell 23 (2), 159-170, 2013 | 398 | 2013 |
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ... Nature genetics 48 (3), 253-264, 2016 | 324 | 2016 |
TRIM24 is an oncogenic transcriptional activator in prostate cancer AC Groner, L Cato, J de Tribolet-Hardy, T Bernasocchi, H Janouskova, ... Cancer cell 29 (6), 846-858, 2016 | 258 | 2016 |
Tagmentation-based whole-genome bisulfite sequencing Q Wang, L Gu, A Adey, B Radlwimmer, W Wang, V Hovestadt, M Bähr, ... Nature protocols 8 (10), 2022-2032, 2013 | 180 | 2013 |
Suppression of enhancer overactivation by a RACK7-histone demethylase complex H Shen, W Xu, R Guo, B Rong, L Gu, Z Wang, C He, L Zheng, X Hu, Z Hu, ... Cell 165 (2), 331-342, 2016 | 161 | 2016 |
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ... Cancer discovery 4 (3), 348-361, 2014 | 161 | 2014 |
Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia C Baer, R Claus, LP Frenzel, M Zucknick, YJ Park, L Gu, D Weichenhan, ... Cancer research 72 (15), 3775-3785, 2012 | 160 | 2012 |
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ... Nature genetics 47 (1), 22-30, 2015 | 147 | 2015 |
Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway B Goeppert, C Konermann, CR Schmidt, O Bogatyrova, L Geiselhart, ... Hepatology 59 (2), 544-554, 2014 | 133 | 2014 |
A mouse model of X-linked intellectual disability associated with impaired removal of histone methylation S Iwase, E Brookes, S Agarwal, AI Badeaux, H Ito, CN Vallianatos, ... Cell reports 14 (5), 1000-1009, 2016 | 126 | 2016 |
Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children T Bauer, S Trump, N Ishaque, L Thürmann, L Gu, M Bauer, M Bieg, Z Gu, ... Molecular Systems Biology 12 (3), 861, 2016 | 123 | 2016 |
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing H Chen, L Gu, EA Orellana, Y Wang, J Guo, QI Liu, L Wang, Z Shen, H Wu, ... Cell research 30 (6), 544-547, 2020 | 109 | 2020 |
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications S Jahreis, S Trump, M Bauer, T Bauer, L Thürmann, R Feltens, Q Wang, ... Journal of Allergy and Clinical Immunology 141 (2), 741-753, 2018 | 107 | 2018 |
Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ... Hepatology 69 (5), 2091-2106, 2019 | 79 | 2019 |
Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma CH Shen, SH Kim, S Trousil, DT Frederick, A Piris, P Yuan, L Cai, L Gu, ... Nature medicine 22 (9), 1056-1061, 2016 | 79 | 2016 |
Enhancer-mediated oncogenic function of the menin tumor suppressor in breast cancer KMA Dreijerink, AC Groner, ESM Vos, A Font-Tello, L Gu, D Chi, J Reyes, ... Cell reports 18 (10), 2359-2372, 2017 | 75 | 2017 |