Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death W El-Assaad, J Buteau, ML Peyot, C Nolan, R Roduit, S Hardy, E Joly, ... Endocrinology 144 (9), 4154-4163, 2003 | 779 | 2003 |
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in β-cell adaptation and failure in the etiology of diabetes M Prentki, E Joly, W El-Assaad, R Roduit Diabetes 51 (suppl_3), S405-S413, 2002 | 639 | 2002 |
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA … J Buteau, R Roduit, S Susini, M Prentki Diabetologia 42, 856-864, 1999 | 562 | 1999 |
Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland FP Pralong, R Roduit, G Waeber, E Castillo, F Mosimann, B Thorens, ... Endocrinology 139 (10), 4264-4268, 1998 | 279 | 1998 |
Insulin secretion is regulated by the glucose-dependent production of islet β cell macrophage migration inhibitory factor G Waeber, T Calandra, R Roduit, JA Haefliger, C Bonny, N Thompson, ... Proceedings of the National Academy of Sciences 94 (9), 4782-4787, 1997 | 259 | 1997 |
Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside AK Saha, AJ Schwarsin, R Roduit, F Masse, V Kaushik, K Tornheim, ... Journal of Biological Chemistry 275 (32), 24279-24283, 2000 | 257 | 2000 |
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli R Roduit, C Nolan, C Alarcon, P Moore, A Barbeau, ... Diabetes 53 (4), 1007-1019, 2004 | 248 | 2004 |
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure S Abdelli, J Ansite, R Roduit, T Borsello, I Matsumoto, T Sawada, ... Diabetes 53 (11), 2815-2823, 2004 | 216 | 2004 |
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-α gene in the pancreatic β-cell R Roduit, J Morin, F Massé, L Segall, E Roche, CB Newgard, ... Journal of Biological Chemistry 275 (46), 35799-35806, 2000 | 214 | 2000 |
Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic β cells: comparison with the effects of fatty acids S Gremlich, R Roduit, B Thorens Journal of Biological Chemistry 272 (6), 3216-3222, 1997 | 200 | 1997 |
MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells R Roduit, DF Schorderet Apoptosis 13, 343-353, 2008 | 150 | 2008 |
Glucose and leptin induce apoptosis in human β‐cells and impair glucose‐stimulated insulin secretion through activation of c‐Jun N‐terminal kinases K Maedler, FT Schulthess, C Bielman, T Berney, C Bonny, M Prentki, ... The FASEB Journal 22 (6), 1905-1913, 2008 | 144 | 2008 |
A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice R Roduit, P Masiello, SP Wang, H Li, GA Mitchell, M Prentki Diabetes 50 (9), 1970-1975, 2001 | 137 | 2001 |
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor α transcriptional up-regulation of fatty acid oxidation S Gremlich, C Nolan, R Roduit, R Burcelin, ML Peyot, ... Endocrinology 146 (1), 375-382, 2005 | 120 | 2005 |
Circadian regulation of islet genes involved in insulin production and secretion N Allaman-Pillet, R Roduit, A Oberson, S Abdelli, J Ruiz, JS Beckmann, ... Molecular and cellular endocrinology 226 (1-2), 59-66, 2004 | 111 | 2004 |
Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family P Escher, P Gouras, R Roduit, L Tiab, S Bolay, T Delarive, S Chen, ... Human mutation 30 (3), 342-351, 2009 | 77 | 2009 |
Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin R Roduit, B Thorens FEBS letters 415 (2), 179-182, 1997 | 62 | 1997 |
A unique set of SH3–SH3 interactions controls IB1 homodimerization O Kristensen, S Guenat, I Dar, N Allaman‐Pillet, A Abderrahmani, ... The EMBO journal 25 (4), 785-797, 2006 | 57 | 2006 |
Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes C Roh, R Roduit, B Thorens, S Fried, KV Kandror Journal of Biological Chemistry 276 (38), 35990-35994, 2001 | 47 | 2001 |
Cloning and expression of rat pancreatic β-cell malonyl-CoA decarboxylase N VOILLEY, R RODUIT, R VICARETTI, C BONNY, G WAEBER, ... Biochemical journal 340 (1), 213-217, 1999 | 47 | 1999 |