| Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma S Pellegatta, L Valletta, C Corbetta, M Patanè, I Zucca, F Riccardi Sirtori, ... Acta neuropathologica communications 3, 1-12, 2015 | 128 | 2015 |
| Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and … G Papeo, H Posteri, D Borghi, AA Busel, F Caprera, E Casale, M Ciomei, ... Journal of medicinal chemistry 58 (17), 6875-6898, 2015 | 121 | 2015 |
| [GdPCP2A(H2O)2]-: A Paramagnetic Contrast Agent Designed for Improved Applications in Magnetic Resonance Imaging S Aime, M Botta, L Frullano, S Geninatti Crich, G Giovenzana, R Pagliarin, ... Journal of medicinal chemistry 43 (21), 4017-4024, 2000 | 118 | 2000 |
| A fully automated method for accurate mass determination using high‐performance liquid chromatography with a quadrupole/orthogonal acceleration time‐of‐flight mass spectrometer M Colombo, FR Sirtori, V Rizzo Rapid Communications in Mass Spectrometry 18 (4), 511-517, 2004 | 101 | 2004 |
| Alkylsulfanyl-1, 2, 4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure–activity relationships P Polucci, P Magnaghi, M Angiolini, D Asa, N Avanzi, A Badari, J Bertrand, ... Journal of medicinal chemistry 56 (2), 437-450, 2013 | 95 | 2013 |
| Cell Division Cycle 7 Kinase Inhibitors: 1H-Pyrrolo[2,3-b]pyridines, Synthesis and Structure−Activity Relationships A Ermoli, A Bargiotti, MG Brasca, A Ciavolella, N Colombo, G Fachin, ... Journal of medicinal chemistry 52 (14), 4380-4390, 2009 | 62 | 2009 |
| Nemorubicin and doxorubicin bind the G-quadruplex sequences of the human telomeres and of the c-MYC promoter element Pu22 L Scaglioni, R Mondelli, R Artali, FR Sirtori, S Mazzini Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (6), 1129-1138, 2016 | 56 | 2016 |
| Synthesis of novel simplified sarcodictyin/eleutherobin analogs with potent microtubule-stabilizing activity, using ring closing metathesis as the key-step R Beumer, P Bayón, P Bugada, S Ducki, N Mongelli, FR Sirtori, J Telser, ... Tetrahedron 59 (44), 8803-8820, 2003 | 52 | 2003 |
| Mass Spectrometric Strategies for the Identification and Characterization of Human Serum Albumin Covalently Adducted by Amoxicillin: Ex Vivo Studies D Garzon, A Ariza, L Regazzoni, R Clerici, A Altomare, FR Sirtori, M Carini, ... Chemical research in toxicology 27 (9), 1566-1574, 2014 | 43 | 2014 |
| Thieno [3, 2-c] pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity S Bindi, D Fancelli, C Alli, D Berta, JA Bertrand, AD Cameron, P Cappella, ... Bioorganic & medicinal chemistry 18 (19), 7113-7120, 2010 | 39 | 2010 |
| Synthesis of novel simplified eleutheside analogues with potent microtubule-stabilizing activity, using ring-closing metathesis as the key-step R Beumer, P Bayón, P Bugada, S Ducki, N Mongelli, FR Sirtori, J Telser, ... Tetrahedron letters 44 (4), 681-684, 2003 | 36 | 2003 |
| 6‐Substituted Pyrrolo [3, 4‐c] pyrazoles: An Improved Class of CDK2 Inhibitors MG Brasca, C Albanese, R Amici, D Ballinari, L Corti, V Croci, D Fancelli, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 841-852, 2007 | 31 | 2007 |
| Discovery of stereospecific PARP-1 inhibitor isoindolinone NMS-P515 G Papeo, P Orsini, NR Avanzi, D Borghi, E Casale, M Ciomei, A Cirla, ... ACS Medicinal Chemistry Letters 10 (4), 534-538, 2019 | 28 | 2019 |
| Effect of conjugation site and technique on the stability and pharmacokinetics of antibody-drug conjugates A Kaempffe, S Dickgiesser, N Rasche, A Paoletti, E Bertotti, I De Salve, ... Journal of Pharmaceutical Sciences 110 (12), 3776-3785, 2021 | 18 | 2021 |
| Insights into PARP inhibitors’ selectivity using fluorescence polarization and surface plasmon resonance binding assays G Papeo, N Avanzi, S Bettoni, A Leone, M Paolucci, R Perego, F Quartieri, ... Journal of Biomolecular Screening 19 (8), 1212-1219, 2014 | 17 | 2014 |
| The interaction of nemorubicin metabolite PNU-159682 with DNA fragments d (CGTACG) 2, d (CGATCG) 2 and d (CGCGCG) 2 shows a strong but reversible binding to G: C base pairs S Mazzini, L Scaglioni, R Mondelli, M Caruso, FR Sirtori Bioorganic & medicinal chemistry 20 (24), 6979-6988, 2012 | 17 | 2012 |
| Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90 FR Sirtori, D Caronni, M Colombo, C Dalvit, M Paolucci, L Regazzoni, ... European Journal of Pharmaceutical Sciences 76, 83-94, 2015 | 16 | 2015 |
| Virtual cross-linking of the active nemorubicin metabolite PNU-159682 to double-stranded DNA M Scalabrin, L Quintieri, M Palumbo, F Riccardi Sirtori, B Gatto Chemical Research in Toxicology 30 (2), 614-624, 2017 | 14 | 2017 |
| Development of biochemical assays for the identification of eIF4E-specific inhibitors C Visco, C Perrera, S Thieffine, FR Sirtori, R D’Alessio, P Magnaghi Journal of Biomolecular Screening 17 (5), 581-592, 2012 | 12 | 2012 |
| MS methods to study macromolecule-ligand interaction: Applications in drug discovery FR Sirtori, A Altomare, M Carini, G Aldini, L Regazzoni Methods 144, 152-174, 2018 | 9 | 2018 |
