Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins AE Aplin, A Howe, SK Alahari, RL Juliano Pharmacological reviews 50 (2), 197-264, 1998 | 1343 | 1998 |
Integrin signaling and cell growth control A Howe, AE Aplin, SK Alahari, RL Juliano Current opinion in cell biology 10 (2), 220-231, 1998 | 922 | 1998 |
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation C Rogers, DA Erkes, A Nardone, AE Aplin, T Fernandes-Alnemri, ... Nature communications 10 (1), 1689, 2019 | 624 | 2019 |
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade S Yang, J Wei, YH Cui, G Park, P Shah, Y Deng, AE Aplin, Z Lu, S Hwang, ... Nature communications 10 (1), 2782, 2019 | 549 | 2019 |
Cell adhesion molecules, signal transduction and cell growth AE Aplin, AK Howe, RL Juliano Current opinion in cell biology 11 (6), 737-744, 1999 | 502 | 1999 |
Anchorage-dependent ERK signaling–mechanisms and consequences AK Howe, AE Aplin, RL Juliano Current opinion in genetics & development 12 (1), 30-35, 2002 | 376 | 2002 |
Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis DA Erkes, W Cai, IM Sanchez, TJ Purwin, C Rogers, CO Field, AC Berger, ... Cancer discovery 10 (2), 254-269, 2020 | 325 | 2020 |
Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1 AE Aplin, SA Stewart, RK Assoian, RL Juliano The Journal of cell biology 153 (2), 273-282, 2001 | 321 | 2001 |
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts TH Lin, AE Aplin, Y Shen, Q Chen, M Schaller, L Romer, I Aukhil, ... The Journal of cell biology 136 (6), 1385-1395, 1997 | 316 | 1997 |
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation KM Connor, S Subbaram, KJ Regan, KK Nelson, JE Mazurkiewicz, ... Journal of Biological Chemistry 280 (17), 16916-16924, 2005 | 297 | 2005 |
Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3 EV Abel, KJ Basile, CH Kugel, AK Witkiewicz, K Le, RK Amaravadi, ... The Journal of clinical investigation 123 (5), 2155-2168, 2013 | 271 | 2013 |
In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase‐3β AE Aplin, GM Gibb, JS Jacobsen, JM Gallo, BH Anderton Journal of neurochemistry 67 (2), 699-707, 1996 | 270 | 1996 |
Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles A Aplin, T Jasionowski, DL Tuttle, SE Lenk, WA Dunn Jr Journal of cellular physiology 152 (3), 458-466, 1992 | 244 | 1992 |
Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway AE Aplin, RL Juliano Journal of Cell Science 112 (5), 695-706, 1999 | 236 | 1999 |
Akt3-mediated resistance to apoptosis in B-RAF–targeted melanoma cells Y Shao, AE Aplin Cancer research 70 (16), 6670-6681, 2010 | 232 | 2010 |
Integrin regulation of cell signalling and motility RL Juliano, P Reddig, S Alahari, M Edin, A Howe, A Aplin Biochemical Society Transactions 32 (3), 443-446, 2004 | 204 | 2004 |
Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling KV Bhatt, LS Spofford, G Aram, M McMullen, K Pumiglia, AE Aplin Oncogene 24 (21), 3459-3471, 2005 | 175 | 2005 |
TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells MB Weiss, EV Abel, MM Mayberry, KJ Basile, AC Berger, AE Aplin Cancer research 72 (24), 6382-6392, 2012 | 168 | 2012 |
Mcl-1 is required for melanoma cell resistance to anoikis K Boisvert-Adamo, W Longmate, EV Abel, AE Aplin Molecular Cancer Research 7 (4), 549-556, 2009 | 159 | 2009 |
Hyperactivation of MEK–ERK1/2 signaling and resistance to apoptosis induced by the oncogenic b-RAF inhibitor, PLX4720, in mutant n-RAS melanoma cells FM Kaplan, Y Shao, MM Mayberry, AE Aplin Oncogene 30 (3), 366-371, 2011 | 142 | 2011 |