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The accessible chromatin landscape of the human genome RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ... Nature 489 (7414), 75-82, 2012 | 3093 | 2012 |
The chromatin accessibility landscape of primary human cancers MR Corces, JM Granja, S Shams, BH Louie, JA Seoane, W Zhou, ... Science 362 (6413), eaav1898, 2018 | 987 | 2018 |
A user's guide to the encyclopedia of DNA elements (ENCODE) ENCODE Project Consortium PLoS biology 9 (4), e1001046, 2011 | 855 | 2011 |
A user's guide to the encyclopedia of DNA elements (ENCODE) RM Myers, J Stamatoyannopoulos, M Snyder, I Dunham, RC Hardison, ... PLoS biology 9 (4), 2011 | 676 | 2011 |
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ... Genome research 21 (10), 1757-1767, 2011 | 628 | 2011 |
ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors C Schmidl, AF Rendeiro, NC Sheffield, C Bock Nature methods 12 (10), 963-965, 2015 | 479 | 2015 |
Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics M Farlik, NC Sheffield, A Nuzzo, P Datlinger, A Schönegger, ... Cell reports 10 (8), 1386-1397, 2015 | 457 | 2015 |
LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor NC Sheffield, C Bock Bioinformatics 32 (4), 587-589, 2016 | 396 | 2016 |
Predicting cell-type–specific gene expression from regions of open chromatin A Natarajan, GG Yardımcı, NC Sheffield, GE Crawford, U Ohler Genome research 22 (9), 1711-1722, 2012 | 295 | 2012 |
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space J Klughammer, B Kiesel, T Roetzer, N Fortelny, A Nemc, KH Nenning, ... Nature medicine 24 (10), 1611-1624, 2018 | 263 | 2018 |
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions NC Sheffield, RE Thurman, L Song, A Safi, JA Stamatoyannopoulos, ... Genome research 23 (5), 777-788, 2013 | 263 | 2013 |
A comparative analysis of mitochondrial genomes in Coleoptera (Arthropoda: Insecta) and genome descriptions of six new beetles NC Sheffield, H Song, SL Cameron, MF Whiting Molecular biology and evolution 25 (11), 2499-2509, 2008 | 262 | 2008 |
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ... Nature medicine 23 (3), 386-395, 2017 | 229 | 2017 |
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1 EM Tomazou, NC Sheffield, C Schmidl, M Schuster, A Schönegger, ... Cell reports 10 (7), 1082-1095, 2015 | 223 | 2015 |
Nonstationary evolution and compositional heterogeneity in beetle mitochondrial phylogenomics NC Sheffield, H Song, SL Cameron, MF Whiting Systematic Biology 58 (4), 381-394, 2009 | 178 | 2009 |
When phylogenetic assumptions are violated: base compositional heterogeneity and among‐site rate variation in beetle mitochondrial phylogenomics H Song, NC Sheffield, SL Cameron, KB Miller, MF Whiting Systematic Entomology 35 (3), 429-448, 2010 | 161 | 2010 |
Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection Y Shibata, NC Sheffield, O Fedrigo, CC Babbitt, M Wortham, AK Tewari, ... PLoS genetics 8 (6), e1002789, 2012 | 160 | 2012 |
GA4GH: International policies and standards for data sharing across genomic research and healthcare HL Rehm, AJH Page, L Smith, JB Adams, G Alterovitz, LJ Babb, ... Cell genomics 1 (2), 2021 | 149 | 2021 |
Multi-omics of single cells: strategies and applications C Bock, M Farlik, NC Sheffield Trends in biotechnology 34 (8), 605-608, 2016 | 142 | 2016 |