Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction KA Fitzgerald, EM Palsson-McDermott, AG Bowie, CA Jefferies, ... Nature 413 (6851), 78-83, 2001 | 1693 | 2001 |
Epstein–Barr virus and Burkitt lymphoma G Brady, GJ MacArthur, PJ Farrell Postgraduate medical journal 84 (993), 372-377, 2008 | 397 | 2008 |
Transactivation by the p65 subunit of NF-κB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1 C Jefferies, A Bowie, G Brady, EL Cooke, X Li, LAJ O'Neill Molecular and cellular biology 21 (14), 4544-4552, 2001 | 112 | 2001 |
Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1 G Brady, L Boggan, A Bowie, LAJ O'Neill Journal of Biological Chemistry 280 (35), 30723-30734, 2005 | 109 | 2005 |
Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2 W Lucchesi, G Brady, O Dittrich-Breiholz, M Kracht, R Russ, PJ Farrell Journal of virology 82 (15), 7456-7466, 2008 | 106 | 2008 |
Low density granulocytes in ANCA vasculitis are heterogenous and hypo-responsive to anti-myeloperoxidase antibodies A Ui Mhaonaigh, AM Coughlan, A Dwivedi, J Hartnett, J Cabral, B Moran, ... Frontiers in immunology 10, 2603, 2019 | 59 | 2019 |
Downregulation of RUNX1 by RUNX3 requires the RUNX3 VWRPY sequence and is essential for Epstein-Barr virus-driven B-cell proliferation G Brady, HJ Whiteman, LC Spender, PJ Farrell Journal of virology 83 (13), 6909-6916, 2009 | 54 | 2009 |
Innate immune activation of NFκB and its antagonism by poxviruses G Brady, AG Bowie Cytokine & growth factor reviews 25 (5), 611-620, 2014 | 52 | 2014 |
Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence C Gubser, R Goodbody, A Ecker, G Brady, LAJ O'Neill, N Jacobs, ... Journal of general virology 88 (6), 1667-1676, 2007 | 50 | 2007 |
Regulation of IRF3 activation in human antiviral signaling pathways MAL Hamrashdi, G Brady Biochemical Pharmacology 200, 115026, 2022 | 45 | 2022 |
Molluscum contagiosum virus protein MC005 inhibits NF-κB activation by targeting NEMO-regulated IκB kinase activation G Brady, DA Haas, PJ Farrell, A Pichlmair, AG Bowie Journal of Virology 91 (15), 10.1128/jvi. 00545-17, 2017 | 39 | 2017 |
Targeting of the cGAS-STING system by DNA viruses T Phelan, MA Little, G Brady Biochemical pharmacology 174, 113831, 2020 | 38 | 2020 |
Poxvirus protein MC132 from molluscum contagiosum virus inhibits NF-κB activation by targeting p65 for degradation G Brady, DA Haas, PJ Farrell, A Pichlmair, AG Bowie Journal of Virology 89 (16), 8406-8415, 2015 | 38 | 2015 |
Previous SARS-CoV-2 infection, age, and frailty are associated with 6-month vaccine-induced anti-spike antibody titer in nursing home residents AH Dyer, C Noonan, M McElheron, I Batten, C Reddy, E Connolly, ... Journal of the American Medical Directors Association 23 (3), 434-439, 2022 | 29 | 2022 |
Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7 L Gu, D Casserly, G Brady, S Carpenter, AP Bracken, KA Fitzgerald, ... Nature Communications 13 (1), 14, 2022 | 25 | 2022 |
Novel function of the unique N-terminal region of RUNX1c in B cell growth regulation G Brady, C Elgueta Karstegl, PJ Farrell Nucleic acids research 41 (3), 1555-1568, 2013 | 23 | 2013 |
RUNX3‐mediated repression of RUNX1 in B cells G Brady, PJ Farrell Journal of cellular physiology 221 (2), 283-287, 2009 | 21 | 2009 |
Bifurcation of signalling in human innate immune pathways to NF-kB and IRF family activation A Kusiak, G Brady Biochemical Pharmacology 205, 115246, 2022 | 20 | 2022 |
Poxviral targeting of interferon regulatory factor activation C Lawler, G Brady Viruses 12 (10), 1191, 2020 | 15 | 2020 |
Dynamic assay for profiling anti-SARS-CoV-2 antibodies and their ACE2/Spike RBD neutralization capacity T Phelan, J Dunne, N Conlon, CN Cheallaigh, WM Abbott, ... Viruses 13 (7), 1371, 2021 | 13 | 2021 |