Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase EM Palmieri, M Gonzalez-Cotto, WA Baseler, LC Davies, B Ghesquière, ... Nature communications 11 (1), 698, 2020 | 293 | 2020 |
Pharmacologic or genetic targeting of glutamine synthetase skews macrophages toward an M1-like phenotype and inhibits tumor metastasis EM Palmieri, A Menga, R Martín-Pérez, A Quinto, C Riera-Domingo, ... Cell reports 20 (7), 1654-1666, 2017 | 292 | 2017 |
Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression CM Rice, LC Davies, JJ Subleski, N Maio, M Gonzalez-Cotto, C Andrews, ... Nature communications 9 (1), 5099, 2018 | 250 | 2018 |
Nitric oxide in macrophage immunometabolism: hiding in plain sight EM Palmieri, C McGinity, DA Wink, DW McVicar Metabolites 10 (11), 429, 2020 | 134 | 2020 |
Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation EM Palmieri, I Spera, A Menga, V Infantino, V Porcelli, V Iacobazzi, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (8), 729-738, 2015 | 98 | 2015 |
Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels LC Davies, CM Rice, EM Palmieri, PR Taylor, DB Kuhns, DW McVicar Nature communications 8 (1), 2074, 2017 | 95 | 2017 |
Blockade of glutamine synthetase enhances inflammatory response in microglial cells EM Palmieri, A Menga, A Lebrun, DC Hooper, DA Butterfield, M Mazzone, ... Antioxidants & redox signaling 26 (8), 351-363, 2017 | 75 | 2017 |
Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level V Somasundaram, AC Gilmore, D Basudhar, EM Palmieri, DA Scheiblin, ... Redox Biology 28, 101354, 2020 | 50 | 2020 |
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism A Menga, EM Palmieri, A Cianciulli, V Infantino, M Mazzone, A Scilimati, ... The FEBS Journal 284 (6), 967-984, 2017 | 41 | 2017 |
TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation WH Tong, N Maio, DL Zhang, EM Palmieri, H Ollivierre, MC Ghosh, ... Blood advances 2 (10), 1146-1156, 2018 | 34 | 2018 |
Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels EM Palmieri, I Spera, A Menga, V Infantino, V Iacobazzi, A Castegna FEBS letters 588 (24), 4807-4814, 2014 | 34 | 2014 |
Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages A Menga, M Serra, S Todisco, C Riera‐Domingo, U Ammarah, M Ehling, ... EMBO Molecular Medicine 12 (10), e11210, 2020 | 33 | 2020 |
Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells E Profilo, LE Peña-Altamira, M Corricelli, A Castegna, A Danese, G Agrimi, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (6 …, 2017 | 31 | 2017 |
Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins DA Butterfield, EM Palmieri, A Castegna Expert review of proteomics 13 (3), 259-274, 2016 | 26 | 2016 |
Nitric oxide modulates metabolic processes in the tumor immune microenvironment CL McGinity, EM Palmieri, V Somasundaram, DD Bhattacharyya, ... International Journal of Molecular Sciences 22 (13), 7068, 2021 | 23 | 2021 |
Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses JF Walls, JJ Subleski, EM Palmieri, M Gonzalez-Cotto, CM Gardiner, ... Elife 9, e59166, 2020 | 22 | 2020 |
Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice JM Weiss, EM Palmieri, M Gonzalez-Cotto, IA Bettencourt, EL Megill, ... Nature Metabolism 5 (6), 981-995, 2023 | 21 | 2023 |
Monoamine oxidase-dependent histamine catabolism accounts for post-ischemic cardiac redox imbalance and injury V Costiniti, I Spera, R Menabò, EM Palmieri, A Menga, P Scarcia, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (9 …, 2018 | 20 | 2018 |
TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient … M Gonzalez-Cotto, L Guo, M Karwan, SK Sen, J Barb, CJ Collado, ... Frontiers in immunology 11, 397, 2020 | 19 | 2020 |
Mitochondrial carriers in inflammation induced by bacterial endotoxin and cytokines V Iacobazzi, V Infantino, A Castegna, A Menga, EM Palmieri, P Convertini, ... Biological chemistry 398 (3), 303-317, 2017 | 18 | 2017 |