Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing JJ Lima, CD Thomas, J Barbarino, Z Desta, SL Van Driest, N El Rouby, ... Clinical Pharmacology & Therapeutics 109 (6), 1417-1423, 2021 | 261 | 2021 |
It's time to reverse our thinking: the reverse translation research paradigm V Shakhnovich Clinical and translational science 11 (2), 98, 2018 | 62 | 2018 |
Anti-TNF, infliximab, and adalimumab can be effective in eosinophilic bowel disease D Turner, VM Wolters, RK Russell, V Shakhnovich, AM Muise, O Ledder, ... Journal of pediatric gastroenterology and nutrition 56 (5), 492-497, 2013 | 48 | 2013 |
How to conduct clinical trials in children: a tutorial V Shakhnovich, CP Hornik, GL Kearns, J Weigel, SM Abdel‐Rahman Clinical and Translational Science 12 (3), 218-230, 2019 | 31 | 2019 |
Obese children require lower doses of pantoprazole than nonobese peers to achieve equal systemic drug exposures V Shakhnovich, PB Smith, JT Guptill, LP James, DN Collier, H Wu, ... The Journal of pediatrics 193, 102-108. e1, 2018 | 31 | 2018 |
Drug dose selection in pediatric obesity: available information for the most commonly prescribed drugs to children KE Kyler, J Wagner, C Hosey-Cojocari, K Watt, V Shakhnovich Pediatric Drugs 21 (5), 357-369, 2019 | 29 | 2019 |
Decreased pregnane X receptor expression in children with active Crohn’s disease V Shakhnovich, C Vyhlidal, C Friesen, A Hildreth, V Singh, J Daniel, ... Drug Metabolism and Disposition 44 (7), 1066-1069, 2016 | 25 | 2016 |
Exome analysis of rare and common variants within the NOD signaling pathway G Andreoletti, V Shakhnovich, K Christenson, T Coelho, R Haggarty, ... Scientific reports 7 (1), 46454, 2017 | 21 | 2017 |
Immunogenicity in clinical practice and drug development: when is it significant? V Shakhnovich, B Meibohm, A Rosenberg, AM Kierzek, R Hasenkamp, ... Clinical and translational science 13 (2), 219, 2019 | 20 | 2019 |
Lean body weight dosing avoids excessive systemic exposure to proton pump inhibitors for children with obesity V Shakhnovich, S Abdel‐Rahman, CA Friesen, J Weigel, RE Pearce, ... Pediatric obesity 14 (1), e12459, 2019 | 20 | 2019 |
A population-based pharmacokinetic model approach to pantoprazole dosing for obese children and adolescents V Shakhnovich, P Brian Smith, JT Guptill, LP James, DN Collier, H Wu, ... Pediatric Drugs 20, 483-495, 2018 | 20 | 2018 |
Failure of proton pump inhibitors to treat GERD in neonates and infants: a question of drug, diagnosis, or design V Shakhnovich, RM Ward, GL Kearns Clinical Pharmacology & Therapeutics 92 (3), 388-392, 2012 | 15 | 2012 |
Efficacy of weight reduction on pediatric nonalcoholic fatty liver disease: opportunities to improve treatment outcomes through pharmacotherapy CS Friesen, C Hosey-Cojocari, SS Chan, IL Csanaky, JB Wagner, ... Frontiers in Endocrinology 12, 663351, 2021 | 14 | 2021 |
# Science: the potential and the challenges of utilizing social media and other electronic communication platforms in health care V Gijsen, M Maddux, A Lavertu, G Gonzalez‐Hernandez, N Ram, ... Clinical and Translational Science 13 (1), 26-30, 2020 | 14 | 2020 |
Investigation of potential early histologic markers of pediatric inflammatory bowel disease JA Bass, CA Friesen, AD Deacy, NA Neilan, JM Bracken, V Shakhnovich, ... BMC gastroenterology 15, 1-7, 2015 | 14 | 2015 |
Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study RS Funk, V Shakhnovich, YK Cho, K Polireddy, T Jausurawong, K Gress, ... Pediatric Rheumatology 19 (1), 62, 2021 | 11 | 2021 |
Effect of Crohn’s disease on villous length and CYP3A4 expression in the pediatric small intestine CA Vyhlidal, BD Chapron, A Ahmed, V Singh, R Casini, V Shakhnovich Clinical and translational science 14 (2), 729-736, 2021 | 11 | 2021 |
A population physiologically‐based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab HP Chang, V Shakhnovich, A Frymoyer, RS Funk, ML Becker, KT Park, ... British journal of clinical pharmacology 88 (1), 290-302, 2022 | 10 | 2022 |
Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation study C Hosey‐Cojocari, SS Chan, CS Friesen, A Robinson, V Williams, ... Clinical and translational science 14 (5), 2008-2016, 2021 | 9 | 2021 |
Potential role of methotrexate polyglutamates in therapeutic drug monitoring for pediatric inflammatory bowel disease R Morrow, R Funk, M Becker, A Sherman, L Van Haandel, T Hudson, ... Pharmaceuticals 14 (5), 463, 2021 | 6 | 2021 |