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Valentina Shakhnovich
Valentina Shakhnovich
Ironwood Pharmaceuticals
在 ironwoodpharma.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing
JJ Lima, CD Thomas, J Barbarino, Z Desta, SL Van Driest, N El Rouby, ...
Clinical Pharmacology & Therapeutics 109 (6), 1417-1423, 2021
2612021
It's time to reverse our thinking: the reverse translation research paradigm
V Shakhnovich
Clinical and translational science 11 (2), 98, 2018
622018
Anti-TNF, infliximab, and adalimumab can be effective in eosinophilic bowel disease
D Turner, VM Wolters, RK Russell, V Shakhnovich, AM Muise, O Ledder, ...
Journal of pediatric gastroenterology and nutrition 56 (5), 492-497, 2013
482013
How to conduct clinical trials in children: a tutorial
V Shakhnovich, CP Hornik, GL Kearns, J Weigel, SM Abdel‐Rahman
Clinical and Translational Science 12 (3), 218-230, 2019
312019
Obese children require lower doses of pantoprazole than nonobese peers to achieve equal systemic drug exposures
V Shakhnovich, PB Smith, JT Guptill, LP James, DN Collier, H Wu, ...
The Journal of pediatrics 193, 102-108. e1, 2018
312018
Drug dose selection in pediatric obesity: available information for the most commonly prescribed drugs to children
KE Kyler, J Wagner, C Hosey-Cojocari, K Watt, V Shakhnovich
Pediatric Drugs 21 (5), 357-369, 2019
292019
Decreased pregnane X receptor expression in children with active Crohn’s disease
V Shakhnovich, C Vyhlidal, C Friesen, A Hildreth, V Singh, J Daniel, ...
Drug Metabolism and Disposition 44 (7), 1066-1069, 2016
252016
Exome analysis of rare and common variants within the NOD signaling pathway
G Andreoletti, V Shakhnovich, K Christenson, T Coelho, R Haggarty, ...
Scientific reports 7 (1), 46454, 2017
212017
Immunogenicity in clinical practice and drug development: when is it significant?
V Shakhnovich, B Meibohm, A Rosenberg, AM Kierzek, R Hasenkamp, ...
Clinical and translational science 13 (2), 219, 2019
202019
Lean body weight dosing avoids excessive systemic exposure to proton pump inhibitors for children with obesity
V Shakhnovich, S Abdel‐Rahman, CA Friesen, J Weigel, RE Pearce, ...
Pediatric obesity 14 (1), e12459, 2019
202019
A population-based pharmacokinetic model approach to pantoprazole dosing for obese children and adolescents
V Shakhnovich, P Brian Smith, JT Guptill, LP James, DN Collier, H Wu, ...
Pediatric Drugs 20, 483-495, 2018
202018
Failure of proton pump inhibitors to treat GERD in neonates and infants: a question of drug, diagnosis, or design
V Shakhnovich, RM Ward, GL Kearns
Clinical Pharmacology & Therapeutics 92 (3), 388-392, 2012
152012
Efficacy of weight reduction on pediatric nonalcoholic fatty liver disease: opportunities to improve treatment outcomes through pharmacotherapy
CS Friesen, C Hosey-Cojocari, SS Chan, IL Csanaky, JB Wagner, ...
Frontiers in Endocrinology 12, 663351, 2021
142021
# Science: the potential and the challenges of utilizing social media and other electronic communication platforms in health care
V Gijsen, M Maddux, A Lavertu, G Gonzalez‐Hernandez, N Ram, ...
Clinical and Translational Science 13 (1), 26-30, 2020
142020
Investigation of potential early histologic markers of pediatric inflammatory bowel disease
JA Bass, CA Friesen, AD Deacy, NA Neilan, JM Bracken, V Shakhnovich, ...
BMC gastroenterology 15, 1-7, 2015
142015
Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study
RS Funk, V Shakhnovich, YK Cho, K Polireddy, T Jausurawong, K Gress, ...
Pediatric Rheumatology 19 (1), 62, 2021
112021
Effect of Crohn’s disease on villous length and CYP3A4 expression in the pediatric small intestine
CA Vyhlidal, BD Chapron, A Ahmed, V Singh, R Casini, V Shakhnovich
Clinical and translational science 14 (2), 729-736, 2021
112021
A population physiologically‐based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab
HP Chang, V Shakhnovich, A Frymoyer, RS Funk, ML Becker, KT Park, ...
British journal of clinical pharmacology 88 (1), 290-302, 2022
102022
Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation study
C Hosey‐Cojocari, SS Chan, CS Friesen, A Robinson, V Williams, ...
Clinical and translational science 14 (5), 2008-2016, 2021
92021
Potential role of methotrexate polyglutamates in therapeutic drug monitoring for pediatric inflammatory bowel disease
R Morrow, R Funk, M Becker, A Sherman, L Van Haandel, T Hudson, ...
Pharmaceuticals 14 (5), 463, 2021
62021
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