SAVER: gene expression recovery for single-cell RNA sequencing M Huang, J Wang, E Torre, H Dueck, S Shaffer, R Bonasio, JI Murray, ... Nature Methods 15 (7), 539-542, 2018 | 664 | 2018 |
Systematic analysis of splice-site-creating mutations in cancer RG Jayasinghe, S Cao, Q Gao, MC Wendl, NS Vo, SM Reynolds, Y Zhao, ... Cell reports 23 (1), 270-281. e3, 2018 | 223 | 2018 |
Data Denoising with transfer learning in single-cell transcriptomics J Wang, D Agarwal, M Huang, G Hu, Z Zhou, C Ye, NR Zhang Nature Methods 16 (9), 875-878, 2019 | 168 | 2019 |
Gene expression distribution deconvolution in single-cell RNA sequencing J Wang, M Huang, E Torre, H Dueck, S Shaffer, J Murray, A Raj, M Li, ... Proceedings of the National Academy of Sciences 115 (28), E6437-E6446, 2018 | 124 | 2018 |
Design of an expression system to enhance MBP-mediated crystallization T Jin, W Chuenchor, J Jiang, J Cheng, Y Li, K Fang, M Huang, P Smith, ... Scientific reports 7, 40991, 2017 | 54 | 2017 |
Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study JS Weber, MS Carlino, A Khattak, T Meniawy, G Ansstas, MH Taylor, ... The Lancet 403 (10427), 632-644, 2024 | 48 | 2024 |
MicrobiomeExplorer: an R package for the analysis and visualization of microbial communities J Reeder, M Huang, JS Kaminker, JN Paulson Bioinformatics 37 (9), 1317-1318, 2021 | 22 | 2021 |
Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study GP Gregory, S Kumar, D Wang, D Mahadevan, P Walker, ... Blood advances 6 (4), 1232-1242, 2022 | 19 | 2022 |
The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces T Jin, M Huang, P Smith, J Jiang, TS Xiao Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 18 | 2013 |
Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein T Jin, M Huang, P Smith, J Jiang, TS Xiao Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 13 | 2013 |
Dimension reduction and denoising of single-cell RNA sequencing data in the presence of observed confounding variables M Huang, Z Zhang, NR Zhang bioRxiv, 2020.08. 03.234765, 2020 | 12 | 2020 |
Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction T Jin, M Huang, J Jiang, P Smith, TS Xiao PloS one 13 (1), e0190547, 2018 | 10 | 2018 |
73P Association between homologous recombination repair mutations and response to pembrolizumab (pembro) plus olaparib (ola) in metastatic castration-resistant prostate cancer … E Yu, JM Piulats, G Gravis, P Fong, T Todenhöfer, B Laguerre, J Arranz, ... Annals of Oncology 32, S387, 2021 | 8 | 2021 |
BreakPoint Surveyor: a pipeline for structural variant visualization MA Wyczalkowski, KM Wylie, S Cao, MD McLellan, J Flynn, M Huang, ... Bioinformatics 33 (19), 3121-3122, 2017 | 5 | 2017 |
Phase 1b study of pan‐AKT inhibitor vevorisertib alone or with paclitaxel or fulvestrant in PIK3CA/AKT/PTEN‐mutated advanced solid tumors S Pant, E Hamilton, SV Ulahannan, JF Strauss, FS Braiteh, M Huang, ... Cancer 129 (12), 1919-1929, 2023 | 2 | 2023 |
Phase 1b Trial of Anti-Immunoglobulin-like Transcript 3 Monoclonal Antibody MK-0482 Monotherapy in Relapsed/Refractory Acute Myeloid Leukemia and Chronic Myelomonocytic Leukemia GC Issa, D Lavie, A Przespolewski, SK George, M Huang, M Chen Blood 140 (Supplement 1), 11759-11760, 2022 | 1 | 2022 |
Online Single-cell RNA-seq Data Denoising with Transfer Learning B Kang, E Abeysinghe, D Agarwal, Q Wang, S Pamidighantam, M Huang, ... Practice and Experience in Advanced Research Computing, 469-472, 2020 | 1 | 2020 |
A Statistical Framework for Denoising Single-cell RNA Sequencing Data M Huang University of Pennsylvania, 2020 | 1 | 2020 |
Statistical Interpretation and Comparison of Waterfall Plots M Huang, C Chen, LZ Sun JCO Clinical Cancer Informatics 7, e2300132, 2023 | | 2023 |
116TiP KEYNOTE-B98: Phase Ib/II study of pembrolizumab plus investigational agents as second-line treatment for anti–PD-1/PD-L1-refractory extensive-stage small cell lung … WCV Lai, MJ Ahn, T Shentzer, D Kowalski, BC Cho, S Schmid, M Jové, ... Annals of Oncology 32, S1425-S1426, 2021 | | 2021 |