An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications J Millul, G Bassi, J Mock, A Elsayed, C Pellegrino, A Zana, S Dakhel Plaza, ... Proceedings of the National Academy of Sciences 118 (16), e2101852118, 2021 | 77 | 2021 |
A DNA‐encoded chemical library based on peptide macrocycles Y Onda, G Bassi, A Elsayed, F Ulrich, S Oehler, L Plais, J Scheuermann, ... Chemistry–A European Journal 27 (24), 7160-7167, 2021 | 29 | 2021 |
A dimeric FAP-targeting small-molecule radioconjugate with high and prolonged tumor uptake A Galbiati, A Zana, M Bocci, J Millul, A Elsayed, J Mock, D Neri, ... Journal of Nuclear Medicine 63 (12), 1852-1858, 2022 | 28 | 2022 |
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody L Nadal, F Peissert, A Elsayed, T Weiss, T Look, M Weller, G Piro, ... Journal for ImmunoTherapy of Cancer 10 (9), 2022 | 11 | 2022 |
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition S Oehler, L Lucaroni, F Migliorini, A Elsayed, L Prati, S Puglioli, M Matasci, ... Nature Chemistry 15 (10), 1431-1443, 2023 | 8 | 2023 |
Fibroblast activation protein triggers release of drug payload from non-internalizing small molecule drug conjugates in solid tumors A Zana, A Galbiati, E Gilardoni, M Bocci, J Millul, T Sturm, R Stucchi, ... Clinical Cancer Research 28 (24), 5440-5454, 2022 | 8 | 2022 |
Selection of a PD‐1 blocking antibody from a novel fully human phage display library F Peissert, L Plüss, AM Giudice, T Ongaro, A Villa, A Elsayed, L Nadal, ... Protein Science 31 (12), e4486, 2022 | 6 | 2022 |
Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen L Plüss, F Peissert, A Elsayed, G Rotta, J Römer, S Dakhel Plaza, A Villa, ... MAbs 15 (1), 2217964, 2023 | 3 | 2023 |
Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology F Peissert, M Pedotti, R Corbellari, L Simonelli, R De Gasparo, ... Global Challenges 7 (10), 2300088, 2023 | 3 | 2023 |
A novel strategy to generate immunocytokines with activity-on-demand using small molecule inhibitors G Rotta, E Gilardoni, D Ravazza, J Mock, F Seehusen, A Elsayed, E Puca, ... EMBO Molecular Medicine 16 (4), 904-926, 2024 | 2 | 2024 |
Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties A Elsayed, C Pellegrino, L Plüss, F Peissert, R Benz, F Ulrich, ... MAbs 15 (1), 2220839, 2023 | 1 | 2023 |
1093 A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer L Nadal, F Peissert, A Elsayed, T Weiss, T Look, M Weller, G Piro, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Bispecific Antibodies for the Treatment of Colorectal Cancer A Elsayed ETH Zurich, 2024 | | 2024 |
Optimizing the Design and Geometry of T Cell–Engaging Bispecific Antibodies Targeting CEA in Colorectal Cancer A Elsayed, L Plüss, L Nideroest, G Rotta, M Thoma, N Zangger, F Peissert, ... Molecular Cancer Therapeutics, OF1-OF11, 2024 | | 2024 |
Anti-cd28 antibodies DE Roberto, A ELSAYED, F PEISSERT, L PLUSS | | 2024 |
A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer L Nadal, F Peissert, A Elsayed, T Weiss, T Look, M Weller, G Piro, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 10, A1136-A1136, 2022 | | 2022 |
1074 A novel fully human CD28 antibody that cross-reacts with CTLA-4 and mouse CD28 for potential applications in cancer immunotherapy A Elsayed, F Peissert, L Plüss, F Ulrich, E Puca, R De Luca, C Halin, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
A novel dimeric small molecule-radio conjugate targeting fibroblast activation protein with high and prolonged tumor uptake S Cazzamalli, A Galbiati, A Zana, M Bocci, J Millul, J Mock, A Elsayed, ... CANCER RESEARCH 82 (12), 2022 | | 2022 |
Abstract LB527: A novel dimeric small molecule-radio conjugate targeting fibroblast activation protein with high and prolonged tumor uptake S Cazzamalli, A Galbiati, A Zana, M Bocci, J Millul, J Mock, A Elsayed, ... Cancer Research 82 (12_Supplement), LB527-LB527, 2022 | | 2022 |
Abstract LB535: A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer L Nadal, F Peissert, A Elsayed, C Libbra, D Neri, R De Luca Cancer Research 82 (12_Supplement), LB535-LB535, 2022 | | 2022 |