Distinct mechanism for antidepressant activity by blockade of central substance P receptors MS Kramer, N Cutler, J Feighner, R Shrivastava, J Carman, JJ Sramek, ... Science 281 (5383), 1640-1645, 1998 | 1367 | 1998 |
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways AN Akopian, V Souslova, S England, K Okuse, N Ogata, J Ure, A Smith, ... Nature neuroscience 2 (6), 541-548, 1999 | 995 | 1999 |
NK1 (substance P) receptor antagonists–why are they not analgesic in humans? R Hill Trends in pharmacological sciences 21 (7), 244-246, 2000 | 554 | 2000 |
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors V Souslova, P Cesare, Y Ding, AN Akopian, L Stanfa, R Suzuki, ... Nature 407 (6807), 1015-1017, 2000 | 526 | 2000 |
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn S Boyce, A Wyatt, JK Webb, R O’donnell, G Mason, M Rigby, ... Neuropharmacology 38 (5), 611-623, 1999 | 461 | 1999 |
Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate … CC Chan, S Boyce, C Brideau, AW Ford-Hutchinson, R Gordon, D Guay, ... Journal of Pharmacology and Experimental Therapeutics 274 (3), 1531-1537, 1995 | 403 | 1995 |
Neurotransmitter candidates of somatosensory primary afferent fibres TE Salt, RG Hill Neuroscience 10 (4), 1083-1103, 1983 | 370 | 1983 |
Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein GR Seabrook, DW Smith, BJ Bowery, A Easter, T Reynolds, SM Fitzjohn, ... Neuropharmacology 38 (3), 349-359, 1999 | 335 | 1999 |
Targeted Disruption of a B2 Bradykinin Receptor Gene in Mice Eliminates Bradykinin Action in Smooth Muscle and Neurons∗ JA Borkowski, RW Ransom, GR Seabrook, M Trumbauer, H Chen, RG Hill, ... Journal of Biological Chemistry 270 (23), 13706-13710, 1995 | 279 | 1995 |
Differential Distribution of 5Ht1D-and 5HT1B-Immunoreactivity within the Human Trigemino-Cerebrovascular System: Implications for the Discovery of New … J Longmore, D Shaw, D Smith, R Hopkins, G McAlliste, JD Pickard, ... Cephalalgia 17 (8), 833-842, 1997 | 276 | 1997 |
Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets FD Tattersall, W Rycroft, B Francis, D Pearce, K Merchant, AM MacLeod, ... Neuropharmacology 35 (8), 1121-1129, 1996 | 249 | 1996 |
Intravital microscope studies on the effects of neurokinin agonists and calcitonin gene-related peptide on dural vessel diameter in the anaesthetized rat DJ Williamson, RJ Hargreaves, RG Hill, SL Shepheard Cephalalgia 17 (4), 518-524, 1997 | 232 | 1997 |
κ‐Opioid agonists produce antinociception after iv and icv but not intrathecal administration in the rat GE Leighton, RE Rodriguez, RG Hill, J Hughes British journal of pharmacology 93 (3), 553-560, 1988 | 224 | 1988 |
Sumatriptan inhibits neurogenic vasodilation of dural blood vessels in the anaesthetized rat‐intravital microscope studies DJ Williamson, RJ Hargreaves, RG Hill, SL Shepheard Cephalalgia 17 (4), 525-531, 1997 | 198 | 1997 |
The behavioural effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats PMB Cahusac, RH Evans, RG Hill, RE Rodriquez, DAS Smith Neuropharmacology 23 (7), 719-724, 1984 | 192 | 1984 |
The cholecystokinin receptor antagonist L364, 718 increases food intake in the rat by attenuation of the action of endogenous cholecystokinin G Hewson, GE Leighton, RG Hill, J Hughes British journal of pharmacology 93 (1), 79-84, 1988 | 191 | 1988 |
Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in Dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats SL Shepheard, DJ Williamson, J Williams, RG Hill, RJ Hargreaves Neuropharmacology 34 (3), 255-261, 1995 | 185 | 1995 |
Rizatriptan has central antinociceptive effects against durally evoked responses MJ Cumberbatch, RG Hill, RJ Hargreaves European journal of pharmacology 328 (1), 37-40, 1997 | 172 | 1997 |
The novel anti-migraine agent rizatriptan inhibits neurogenic dural vasodilation and extravasation DJ Williamson, SL Shepheard, RG Hill, RJ Hargreaves European journal of pharmacology 328 (1), 61-64, 1997 | 172 | 1997 |
The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets FD Tattersall, W Rycroft, M Cumberbatch, G Mason, S Tye, DJ Williamson, ... Neuropharmacology 39 (4), 652-663, 2000 | 169 | 2000 |