Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 10736* | 2016 |
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS DM Pilla, JA Hagar, AK Haldar, AK Mason, D Degrandi, K Pfeffer, ... Proceedings of the National Academy of Sciences 111 (16), 6046-6051, 2014 | 351 | 2014 |
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole A Khaminets, JP Hunn, S Könen‐Waisman, YO Zhao, D Preukschat, ... Cellular microbiology 12 (7), 939-961, 2010 | 219 | 2010 |
Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth J Coers, JC Kagan, M Matthews, H Nagai, DM Zuckman, CR Roy Molecular microbiology 38 (4), 719-736, 2000 | 209 | 2000 |
Interferon-inducible GTPases in host resistance, inflammation and disease D Pilla-Moffett, MF Barber, GA Taylor, J Coers Journal of molecular biology 428 (17), 3495-3513, 2016 | 208 | 2016 |
Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders R Kralovics, AS Buser, SS Teo, J Coers, A Tichelli, APC van der Maas, ... Blood 102 (5), 1869-1871, 2003 | 202 | 2003 |
IRG and GBP host resistance factors target aberrant,“non-self” vacuoles characterized by the missing of “self” IRGM proteins AK Haldar, HA Saka, AS Piro, JD Dunn, SC Henry, GA Taylor, EM Frickel, ... PLoS pathogens 9 (6), e1003414, 2013 | 192 | 2013 |
Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth J Coers, C Monahan, CR Roy Nature cell biology 1 (7), 451-453, 1999 | 185 | 1999 |
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways J Coers, RE Vance, MF Fontana, WF Dietrich Cellular microbiology 9 (10), 2344-2357, 2007 | 181 | 2007 |
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins AK Haldar, C Foltz, R Finethy, AS Piro, EM Feeley, DM Pilla-Moffett, ... Proceedings of the National Academy of Sciences 112 (41), E5628-E5637, 2015 | 168 | 2015 |
Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages R Finethy, I Jorgensen, AK Haldar, MR de Zoete, T Strowig, RA Flavell, ... Infection and immunity 83 (12), 4740-4749, 2015 | 157 | 2015 |
Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems EM Feeley, DM Pilla-Moffett, EE Zwack, AS Piro, R Finethy, JP Kolb, ... Proceedings of the National Academy of Sciences 114 (9), E1698-E1706, 2017 | 146 | 2017 |
Chlamydia muridarum evades growth restriction by the IFN-γ-inducible host resistance factor Irgb10 J Coers, I Bernstein-Hanley, D Grotsky, I Parvanova, JC Howard, ... The Journal of Immunology 180 (9), 6237-6245, 2008 | 142 | 2008 |
Inflammasome activation by bacterial outer membrane vesicles requires guanylate binding proteins R Finethy, S Luoma, N Orench-Rivera, EM Feeley, AK Haldar, ... MBio 8 (5), 10.1128/mbio. 01188-17, 2017 | 139 | 2017 |
The Chlamydia trachomatis inclusion membrane protein CpoS counteracts STING-mediated cellular surveillance and suicide programs BS Sixt, RJ Bastidas, R Finethy, RM Baxter, VK Carpenter, G Kroemer, ... Cell host & microbe 21 (1), 113-121, 2017 | 121 | 2017 |
Canonical inflammasomes drive IFN-γ to prime caspase-11 in defense against a cytosol-invasive bacterium Y Aachoui, Y Kajiwara, IA Leaf, D Mao, JPY Ting, J Coers, A Aderem, ... Cell host & microbe 18 (3), 320-332, 2015 | 121 | 2015 |
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice I Bernstein-Hanley, J Coers, ZR Balsara, GA Taylor, MN Starnbach, ... Proceedings of the National Academy of Sciences 103 (38), 14092-14097, 2006 | 118 | 2006 |
Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions M Kutsch, L Sistemich, CF Lesser, MB Goldberg, C Herrmann, J Coers The EMBO journal 39 (13), e104926, 2020 | 115 | 2020 |
Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility AS Piro, D Hernandez, S Luoma, EM Feeley, R Finethy, A Yirga, ... MBio 8 (6), 10.1128/mbio. 01979-17, 2017 | 100 | 2017 |
The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia-and Toxoplasma-containing vacuoles and host resistance AK Haldar, AS Piro, DM Pilla, M Yamamoto, J Coers PloS one 9 (1), e86684, 2014 | 97 | 2014 |