关注
Yuanli Zhen
Yuanli Zhen
Massachusetts general hospital
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
ABCB6 mutations cause ocular coloboma
L Wang, F He, J Bu, Y Zhen, X Liu, W Du, J Dong, JD Cooney, SK Dubey, ...
The American Journal of Human Genetics 90 (1), 40-48, 2012
1092012
Mutant IDH inhibits IFNγ–TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
MJ Wu, L Shi, J Dubrot, J Merritt, V Vijay, TY Wei, E Kessler, KE Olander, ...
Cancer discovery 12 (3), 812-835, 2022
932022
Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling
N Li, Y Wang, S Neri, Y Zhen, LWR Fong, Y Qiao, X Li, Z Chen, C Stephan, ...
Nature communications 10 (1), 4363, 2019
872019
EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion–positive cholangiocarcinoma
Q Wu, Y Zhen, L Shi, P Vu, P Greninger, R Adil, J Merritt, R Egan, MJ Wu, ...
Cancer discovery 12 (5), 1378-1395, 2022
682022
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer
Y Zhen, Y Zhang, Y Yu
Cell reports 21 (8), 2326-2337, 2017
672017
Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33AD251E mutation
Y Zhen, W Li
Autophagy 11 (9), 1608-1622, 2015
512015
Proteomic analysis of the downstream signaling network of PARP1
Y Zhen, Y Yu
Biochemistry 57 (4), 429-440, 2018
442018
Landscape of clinical resistance mechanisms to FGFR inhibitors in FGFR2-altered cholangiocarcinoma
Q Wu, H Ellis, G Siravegna, AG Michel, BL Norden, F Fece de la Cruz, ...
Clinical Cancer Research 30 (1), 198-208, 2024
232024
Site-specific analysis of the Asp-and Glu-ADP-ribosylated proteome by quantitative mass spectrometry
P Li, Y Zhen, Y Yu
Methods in enzymology 626, 301-321, 2019
222019
Nimbolide targets RNF114 to induce the trapping of PARP1 and synthetic lethality in BRCA-mutated cancer
P Li, Y Zhen, C Kim, Z Liu, J Hao, H Deng, H Deng, M Zhou, XD Wang, ...
Science Advances 9 (43), eadg7752, 2023
152023
EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion–positive cholangiocarcinoma. Cancer Discov. 2022; 12 (5): 1378–1395. doi: 10.1158 …
Q Wu, Y Zhen, L Shi, P Vu, P Greninger, R Adil
CD-21-1168, 0
9
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma
Y Zhen, K Liu, L Shi, S Shah, Q Xu, H Ellis, ER Balasooriya, J Kreuzer, ...
Nature Communications 15 (1), 3805, 2024
42024
Nimbolide targets RNF114 to induce the trapping of PARP1 and poly-ADP-ribosylation-dependent DNA repair factors
P Li, Y Zhen, C Kim, H Deng, H Deng, XD Wang, T Qin, Y Yu
BioRxiv, 2022.10. 04.510815, 2022
32022
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets
V Vijay, N Karisani, L Shi, YH Hung, P Vu, P Kattel, L Kenney, J Merritt, ...
bioRxiv, 2024
22024
Nimbolide analogs and methods of use thereof
Y Yu, QIN Tian, Z Yuanli, P Li, C Kim, H Deng, D Hejun
22022
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations
ER Balasooriya, Q Wu, H Ellis, Y Zhen, BL Norden, RB Corcoran, ...
Clinical Cancer Research 30 (10), 2181-2192, 2024
12024
Construction of recombinant plasmid pCMV-Myc-PIASx? and its protein expression
J LI, J ZHANG, Y ZHEN, N YANG, X LI
Journal of Jilin University (Medicine Edition), 2006
12006
Nimbolide analogs and methods of use thereof
Y Yu, T Qin, Z Yuanli, P Li, KIM Chiho, D Heping, D Hejun
US Patent App. 18/260,653, 2024
2024
Abstract B023: Nimbolide targets RNF114 to induce the trapping of PARP1 and synthetic lethality in BRCA-mutated cancer
P Li, Y Zhen, C Kim, Z Liu, J Hao, H Deng, H Deng, M Zhou, XD Wang, ...
Molecular Cancer Therapeutics 23 (6_Supplement), B023-B023, 2024
2024
Abstract PR002: Nimbolide targets RNF114 to induce the trapping of PARP1 and synthetic lethality in BRCA-mutated cancer
P Li, Y Zhen, C Kim, Z Liu, J Hao, H Deng, H Deng, M Zhou, XD Wang, ...
Molecular Cancer Therapeutics 23 (6_Supplement), PR002-PR002, 2024
2024
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